美股詳情

本頁面由Tiger Trade Technology Pte. Ltd.提供服務

Biofrontera Inc

1.19

-0.1700-12.50%

成交量：148.02萬

成交額：186.54萬

市值：1,767.44萬

市盈率：-2.19

高：1.36

開：1.33

低：1.17

收：1.36

52周最高：1.66

52周最低：0.5547

股本：1,485.24萬

流通股本：1,055.44萬

量比：1.08

換手率：14.02%

股息：- -

股息率：- -

每股收益(TTM):-0.5426

每股收益(LYR):-1.0358

淨資產收益率：-988.35%

總資產收益率：-17.45%

市淨率：2.97

市盈率(LYR):-1.15

資料載入中...

總覽公司新聞資訊公告

SEC問詢函

CORRESP [Cover] - Correspondence

[修訂]招股説明書

S-1/A [Amend] - General form for registration of securities under the Securities Act of 1933

[修訂]招股説明書

S-1/A [Amend] - General form for registration of securities under the Securities Act of 1933

SEC問詢函

CORRESP [Cover] - Correspondence

[修訂]招股説明書

S-1/A [Amend] - General form for registration of securities under the Securities Act of 1933

SEC問詢函

CORRESP [Cover] - Correspondence

SEC問詢函

CORRESP [Cover] - Correspondence

SEC問詢函

CORRESP [Cover] - Correspondence

[修訂]招股説明書

S-1/A [Amend] - General form for registration of securities under the Securities Act of 1933

SEC問詢函

CORRESP [Cover] - Correspondence

SEC問詢函

CORRESP [Cover] - Correspondence

SEC問詢函

CORRESP [Cover] - Correspondence

[修訂]招股説明書

S-1/A [Amend] - General form for registration of securities under the Securities Act of 1933

[補充]招股説明書

FWP - Filing under Securities Act Rules 163/433 of free writing prospectuses

[修訂]招股説明書

S-1/A [Amend] - General form for registration of securities under the Securities Act of 1933

SEC問詢函

CORRESP [Cover] - Correspondence

[修訂]招股説明書

S-1/A [Amend] - General form for registration of securities under the Securities Act of 1933

SEC問詢函

CORRESP [Cover] - Correspondence

[修訂]招股説明書

S-1/A [Amend] - General form for registration of securities under the Securities Act of 1933

SEC問詢函

CORRESP [Cover] - Correspondence

{"basename":"/hant","ssrTDKData":{"titleTemplate":"%s - 老虎證券","title":"老虎证券全球投资理财平台| 一站式投资美股新股港股A股","description":"老虎证券助您一站式投资美股，新股，港股，A股等全球金融理财产品。新加坡华人最信赖的在线投资平台，现在加入即享低费用，24/5 无时差炒美股投资理财！","keywords":"老虎證券,老虎證券開戶,老虎券商,老虎證券官網,老虎證券app,tigertrade老虎證券,股票,炒股,新加坡股票交易平臺,投資,投資理財","social":{"ogDescription":"老虎证券助您一站式投资美股，新股，港股，A股等全球金融理财产品。新加坡华人最信赖的在线投资平台，现在加入即享低费用，24/5 无时差炒美股投资理财！","ogImage":"https://c1.itigergrowtha.com/portal5/static/media/og-logo.0a0bd8dc.png","ogUrl":"https://www.etasphere.com/hant/stock/BFRI/filings?page=10"},"companyName":"老虎證券"},"pageData":{"isMobile":false,"isTiger":false,"isTTM":true,"region":"SGP","license":"TBSG","edition":"fundamental","symbol":"BFRI","isAnalysisPage":false},"__swrFallback__":{"@#url:\"https://hq.skytigris.cn/stock_info/detail/global\",params:#delay:false,,method:\"POST\",data:#items:@#symbol:\"BFRI\",,,,,undefined,":{"symbol":"BFRI","market":"US","secType":"STK","nameCN":"Biofrontera Inc","latestPrice":1.19,"timestamp":1789502400000,"preClose":1.36,"halted":0,"volume":1480214,"delay":0,"changeRate":-0.1250000000000001,"floatShares":10554400,"shares":14852400,"eps":-0.542636,"marketStatus":"盤前交易","change":-0.17,"latestTime":"09-16 04:30:54 EDT","open":1.33,"high":1.36,"low":1.17,"amount":1865384.185475,"amplitude":0.139706,"askPrice":1.45,"askSize":100,"bidPrice":1.1,"bidSize":2040,"shortable":0,"etf":0,"ttmEps":-0.542636,"tradingStatus":1,"nextMarketStatus":{"tag":"開盤","tradingStatus":2,"beginTime":1789565400000},"marketStatusCode":1,"adr":0,"listingDate":1635480000000,"exchange":"NASDAQ","adjPreClose":1.19,"postHourTrading":{"tag":"盘后","latestPrice":1.2499,"preClose":1.19,"latestTime":"19:32 EDT","volume":13791,"amount":16559.9059,"timestamp":1789515146392,"change":0.0599,"changeRate":0.050336,"amplitude":0.067143},"volumeRatio":1.0789840648383011,"impliedVol":4.5485,"impliedVolPercentile":0},"@#url:\"https://hq.skytigris.cn/stock_info/fundamental/all\",params:#delay:false,,method:\"POST\",data:#items:@#symbol:\"BFRI\",,,,,undefined,":{"symbol":"BFRI","floatShares":10554400,"roa":"-17.45%","roe":"-988.35%","lyrEps":-1.035792,"volumeRatio":1.0789840648383011,"shares":14852400,"dividePrice":0,"high":1.36,"amplitude":0.139706,"preClose":1.36,"low":1.17,"week52Low":0.5547,"pbRate":"2.97","psRate":"0.38","week52High":1.66,"institutionHeld":0,"latestPrice":1.19,"committee":0.906542,"eps":-0.542636,"divideRate":0,"volume":1480214,"delay":0,"ttmEps":-0.542636,"open":1.33,"prevYearClose":0.57,"prevWeekClose":1.55,"prevMonthClose":1.53,"prevQuarterClose":0.9455,"fiveDayClose":1.56,"twentyDayClose":1.35,"sixtyDayClose":0.987},"@#url:\"https://hq.skytigris.cn/fundamental/corporate_actions/details/BFRI\",params:#limit:5,,,undefined,":[{"market":"US","date":"2026-08-13","symbol":"BFRI","fiscalQuarterEnding":"2026/06","expectedEps":-0.17,"name":null,"time":"盤前","type":"earning","dateTimestamp":1786593600000,"reportTimeType":"pre","actualEps":-0.05},{"market":"US","date":"2026-05-14","symbol":"BFRI","fiscalQuarterEnding":"2026/03","expectedEps":-0.18,"name":null,"time":"盤前","type":"earning","dateTimestamp":1778731200000,"reportTimeType":"pre","actualEps":-0.41},{"market":"US","date":"2026-03-19","symbol":"BFRI","fiscalQuarterEnding":"2025/12","expectedEps":0.29,"name":null,"time":"盤前","type":"earning","dateTimestamp":1773892800000,"reportTimeType":"pre","actualEps":0.5},{"date":"2026-01-13","symbol":"BFRI","type":"earning","reportTimeType":"pre","market":"US","fiscalQuarterEnding":null,"expectedEps":null,"defaultRemindTime":1768294800000,"name":null,"time":"盤前","dateTimestamp":1768280400000,"actualEps":null},{"market":"US","date":"2025-11-12","symbol":"BFRI","fiscalQuarterEnding":"2025/09","expectedEps":-0.6,"name":null,"time":"盤後","type":"earning","dateTimestamp":1762923600000,"reportTimeType":"post","actualEps":-0.59}],"@#url:\"https://hq.skytigris.cn/fundamental/dividend/history\",params:#symbol:\"BFRI\",market:\"US\",,,undefined,":[],"@#url:\"https://hq.skytigris.cn/fundamental/estimate/recommendation\",params:#symbol:\"BFRI\",market:\"US\",delay:false,,,undefined,":{"strongBuy":0,"buy":1,"hold":0,"sell":0,"strongSell":0,"meanLabel":"BUY","meanPercent":1,"analysts":2,"updateTime":1639627200000},"@#url:\"https://hq.skytigris.cn/value_analysis/stock/BFRI\",params:#withQuantilePoint:true,period:\"5year\",factor:\"peRate\",delay:false,algorithm:1,,,undefined,":{"brief":{"id":"BFRI","date":"2026-09-14","current":-2.192999,"percent":0.074229,"low":-27.116173,"twenty":-1.837333,"median":-0.702867,"eighty":-0.427257,"high":-0.066549,"avg":-1.978712,"sd":4.591246,"marketCap":23021156},"quantilePoints":[{"date":"2021-10-15","current":-6.366969,"twenty":-6.366969,"median":-6.366969,"eighty":-6.366969,"marketCap":66000000},{"date":"2021-10-21","current":-6.366969,"twenty":-6.366969,"median":-6.366969,"eighty":-6.366969,"marketCap":66000000},{"date":"2021-10-29","current":-3.403434,"twenty":-6.366969,"median":-6.366969,"eighty":-5.354042,"marketCap":35280000},{"date":"2021-11-05","current":-3.625699,"twenty":-6.366969,"median":-5.860506,"eighty":-4.229983,"marketCap":37584000},{"date":"2021-11-12","current":-3.771175,"twenty":-6.366969,"median":-4.632838,"eighty":-3.625699,"marketCap":39092000},{"date":"2021-11-19","current":-2.987845,"twenty":-6.366969,"median":-4.106888,"eighty":-3.403434,"marketCap":30972000},{"date":"2021-11-26","current":-8.84044,"twenty":-6.366969,"median":-4.106888,"eighty":-3.354891,"marketCap":91640000},{"date":"2021-12-03","current":-2.642082,"twenty":-6.366969,"median":-3.849508,"eighty":-2.984309,"marketCap":61808860},{"date":"2021-12-10","current":-3.322712,"twenty":-6.366969,"median":-3.597723,"eighty":-2.953711,"marketCap":77731517},{"date":"2021-12-17","current":-4.393157,"twenty":-6.366969,"median":-3.771175,"eighty":-2.966985,"marketCap":102773515},{"date":"2021-12-23","current":-8.148997,"twenty":-6.366969,"median":-3.983793,"eighty":-2.980772,"marketCap":190637633},{"date":"2021-12-31","current":-5.498321,"twenty":-6.366969,"median":-4.249695,"eighty":-3.014276,"marketCap":128627712},{"date":"2022-01-07","current":-3.750849,"twenty":-6.366969,"median":-4.269406,"eighty":-3.139751,"marketCap":87747362},{"date":"2022-01-14","current":-3.61924,"twenty":-6.366969,"median":-4.224944,"eighty":-3.233738,"marketCap":84668507},{"date":"2022-01-21","current":-2.537124,"twenty":-6.366969,"median":-4.076215,"eighty":-3.032863,"marketCap":59353479},{"date":"2022-01-28","current":-2.222725,"twenty":-6.156743,"median":-3.875146,"eighty":-2.952585,"marketCap":51998436},{"date":"2022-02-04","current":-3.209791,"twenty":-5.710021,"median":-3.761012,"eighty":-2.932017,"marketCap":75089848},{"date":"2022-02-11","current":-2.507878,"twenty":-5.507095,"median":-3.625699,"eighty":-2.880769,"marketCap":58669289},{"date":"2022-02-18","current":-2.142298,"twenty":-5.440609,"median":-3.536176,"eighty":-2.727944,"marketCap":50116914},{"date":"2022-02-25","current":-2.251972,"twenty":-5.354042,"median":-3.453019,"eighty":-2.632182,"marketCap":52682626},{"date":"2022-03-04","current":-1.959508,"twenty":-5.295159,"median":-3.3907,"eighty":-2.513727,"marketCap":45840727},{"date":"2022-03-11","current":-1.718225,"twenty":-5.050082,"median":-3.285586,"eighty":-2.38358,"marketCap":40196160},{"date":"2022-03-18","current":-2.156921,"twenty":-4.954188,"median":-3.211653,"eighty":-2.234424,"marketCap":50459009},{"date":"2022-03-25","current":-2.178856,"twenty":-4.721615,"median":-3.089149,"eighty":-2.215414,"marketCap":50972152},{"date":"2022-04-01","current":-2.56637,"twenty":-4.698495,"median":-2.987845,"eighty":-2.216876,"marketCap":60037668},{"date":"2022-04-08","current":-2.095403,"twenty":-4.621682,"median":-2.954079,"eighty":-2.216876,"marketCap":79023940},{"date":"2022-04-14","current":-1.904912,"twenty":-4.577059,"median":-2.947271,"eighty":-2.208102,"marketCap":71839945},{"date":"2022-04-22","current":-1.809666,"twenty":-4.393157,"median":-2.910015,"eighty":-2.164233,"marketCap":68247948},{"date":"2022-04-29","current":-1.678137,"twenty":-4.386649,"median":-2.858834,"eighty":-2.142298,"marketCap":63287571},{"date":"2022-05-06","current":-1.578356,"twenty":-4.300344,"median":-2.763924,"eighty":-2.039935,"marketCap":59524526},{"date":"2022-05-13","current":-1.655607,"twenty":-4.284596,"median":-2.676044,"eighty":-1.88677,"marketCap":47380154},{"date":"2022-05-20","current":-1.907529,"twenty":-4.269406,"median":-2.629707,"eighty":-1.841415,"marketCap":54589677},{"date":"2022-05-27","current":-1.94727,"twenty":-4.229983,"median":-2.580993,"eighty":-1.821426,"marketCap":55726962},{"date":"2022-06-03","current":-1.781685,"twenty":-4.221921,"median":-2.562715,"eighty":-1.814497,"marketCap":50988274},{"date":"2022-06-10","current":-1.516751,"twenty":-4.17222,"median":-2.507878,"eighty":-1.797227,"marketCap":43406375},{"date":"2022-06-17","current":-1.371037,"twenty":-4.025765,"median":-2.460352,"eighty":-1.75891,"marketCap":39236330},{"date":"2022-06-24","current":-1.384283,"twenty":-3.987129,"median":-2.438417,"eighty":-1.718664,"marketCap":39615425},{"date":"2022-07-01","current":-1.192206,"twenty":-3.918605,"median":-2.412827,"eighty":-1.685259,"marketCap":34118548},{"date":"2022-07-08","current":-1.178959,"twenty":-3.864891,"median":-2.354334,"eighty":-1.675378,"marketCap":33739453},{"date":"2022-07-15","current":-1.132596,"twenty":-3.818175,"median":-2.270251,"eighty":-1.649308,"marketCap":32412620},{"date":"2022-07-22","current":-1.251816,"twenty":-3.763045,"median":-2.230037,"eighty":-1.606944,"marketCap":35824475},{"date":"2022-07-29","current":-0.947141,"twenty":-3.724527,"median":-2.215414,"eighty":-1.570914,"marketCap":27105291},{"date":"2022-08-05","current":-1.000128,"twenty":-3.661307,"median":-2.178856,"eighty":-1.410636,"marketCap":28621670},{"date":"2022-08-12","current":-1.286738,"twenty":-3.623115,"median":-2.164233,"eighty":-1.384283,"marketCap":33206853},{"date":"2022-08-19","current":-1.049467,"twenty":-3.599443,"median":-2.156921,"eighty":-1.363089,"marketCap":27083604},{"date":"2022-08-26","current":-1.122474,"twenty":-3.54289,"median":-2.11885,"eighty":-1.300142,"marketCap":28967680},{"date":"2022-09-02","current":-1.085971,"twenty":-3.502605,"median":-2.069182,"eighty":-1.254466,"marketCap":28025642},{"date":"2022-09-09","current":-1.140725,"twenty":-3.482771,"median":-2.003377,"eighty":-1.226648,"marketCap":29438700},{"date":"2022-09-16","current":-0.985587,"twenty":-3.403377,"median":-1.927399,"eighty":-1.212407,"marketCap":25435036},{"date":"2022-09-23","current":-0.842312,"twenty":-3.40066,"median":-1.904912,"eighty":-1.178959,"marketCap":21737536},{"date":"2022-09-30","current":-0.958209,"twenty":-3.388152,"median":-1.893838,"eighty":-1.150374,"marketCap":24728508},{"date":"2022-10-07","current":-1.031216,"twenty":-3.366909,"median":-1.87908,"eighty":-1.122474,"marketCap":26612584},{"date":"2022-10-14","current":-1.104222,"twenty":-3.307862,"median":-1.818114,"eighty":-1.104222,"marketCap":28496661},{"date":"2022-10-21","current":-1.095096,"twenty":-3.246576,"median":-1.813276,"eighty":-1.104222,"marketCap":28261152},{"date":"2022-10-28","current":-0.976461,"twenty":-3.23356,"median":-1.804159,"eighty":-1.093303,"marketCap":25199527},{"date":"2022-11-04","current":-1.034564,"twenty":-3.211281,"median":-1.781685,"eighty":-1.085971,"marketCap":26699002},{"date":"2022-11-11","current":-1.034564,"twenty":-3.19663,"median":-1.754132,"eighty":-1.064069,"marketCap":26699002},{"date":"2022-11-18","current":-2.138512,"twenty":-3.122051,"median":-1.781685,"eighty":-1.069544,"marketCap":26432011},{"date":"2022-11-25","current":-2.138296,"twenty":-3.034313,"median":-1.798653,"eighty":-1.076845,"marketCap":26429342},{"date":"2022-12-02","current":-2.268119,"twenty":-3.031897,"median":-1.811471,"eighty":-1.077913,"marketCap":28033952},{"date":"2022-12-09","current":-2.062476,"twenty":-2.987845,"median":-1.814802,"eighty":-1.085971,"marketCap":25492207},{"date":"2022-12-16","current":-1.706706,"twenty":-2.970163,"median":-1.831421,"eighty":-1.085971,"marketCap":21094881},{"date":"2022-12-23","current":-2.008905,"twenty":-2.954274,"median":-1.841415,"eighty":-1.085971,"marketCap":24830071},{"date":"2022-12-30","current":-1.97996,"twenty":-2.953963,"median":-1.87908,"eighty":-1.08618,"marketCap":24472305},{"date":"2023-01-06","current":-1.944102,"twenty":-2.952429,"median":-1.886392,"eighty":-1.090206,"marketCap":24029101},{"date":"2023-01-13","current":-2.157953,"twenty":-2.946433,"median":-1.900906,"eighty":-1.0942,"marketCap":26672302},{"date":"2023-01-20","current":-1.97348,"twenty":-2.935705,"median":-1.902631,"eighty":-1.095096,"marketCap":24392208},{"date":"2023-01-27","current":-1.983416,"twenty":-2.918789,"median":-1.907529,"eighty":-1.095096,"marketCap":24515023},{"date":"2023-02-03","current":-1.901116,"twenty":-2.907091,"median":-1.90622,"eighty":-1.098746,"marketCap":23497791},{"date":"2023-02-10","current":-1.761356,"twenty":-2.888081,"median":-1.904356,"eighty":-1.104222,"marketCap":21770366},{"date":"2023-02-17","current":-1.769997,"twenty":-2.860297,"median":-1.900906,"eighty":-1.107623,"marketCap":21877162},{"date":"2023-02-24","current":-1.620949,"twenty":-2.849692,"median":-1.893835,"eighty":-1.11285,"marketCap":20034931},{"date":"2023-03-03","current":-1.361087,"twenty":-2.82668,"median":-1.879083,"eighty":-1.113348,"marketCap":16823041},{"date":"2023-03-10","current":-23.153041,"twenty":-2.863221,"median":-1.882738,"eighty":-1.113348,"marketCap":14817946},{"date":"2023-03-17","current":-27.116173,"twenty":-2.939394,"median":-1.9009,"eighty":-1.115173,"marketCap":17354351},{"date":"2023-03-24","current":-25.864658,"twenty":-2.966985,"median":-1.901011,"eighty":-1.122474,"marketCap":16553381},{"date":"2023-03-31","current":-25.447527,"twenty":-3.122051,"median":-1.904912,"eighty":-1.122474,"marketCap":16286417},{"date":"2023-04-06","current":-25.447486,"twenty":-3.239037,"median":-1.907529,"eighty":-1.122474,"marketCap":16286391},{"date":"2023-04-14","current":-24.767495,"twenty":-3.3907,"median":-1.922393,"eighty":-1.1316,"marketCap":15851197},{"date":"2023-04-21","current":-25.038658,"twenty":-3.502605,"median":-1.933302,"eighty":-1.132397,"marketCap":16024741},{"date":"2023-04-28","current":-24.613142,"twenty":-3.637568,"median":-1.944102,"eighty":-1.139099,"marketCap":15752411},{"date":"2023-05-03","current":-24.821728,"twenty":-3.737688,"median":-1.944102,"eighty":-1.14255,"marketCap":15885906},{"date":"2023-05-12","current":-23.549353,"twenty":-3.962064,"median":-1.953389,"eighty":-1.150374,"marketCap":15071586},{"date":"2023-05-19","current":-0.906232,"twenty":-3.870018,"median":-1.944102,"eighty":-1.124299,"marketCap":12396346},{"date":"2023-05-26","current":-0.917357,"twenty":-3.849508,"median":-1.944102,"eighty":-1.113348,"marketCap":12548530},{"date":"2023-06-02","current":-0.907598,"twenty":-3.786842,"median":-1.922717,"eighty":-1.111024,"marketCap":12415035},{"date":"2023-06-09","current":-0.88808,"twenty":-3.758979,"median":-1.922285,"eighty":-1.095096,"marketCap":12148045},{"date":"2023-06-16","current":-0.829525,"twenty":-3.711367,"median":-1.907529,"eighty":-1.086128,"marketCap":11347075},{"date":"2023-06-23","current":-1.10766,"twenty":-3.661307,"median":-1.904634,"eighty":-1.085971,"marketCap":15151683},{"date":"2023-06-30","current":-1.034467,"twenty":-3.624407,"median":-1.901011,"eighty":-1.077059,"marketCap":14150471},{"date":"2023-07-07","current":-0.865634,"twenty":-3.61924,"median":-1.900903,"eighty":-1.058593,"marketCap":11841006},{"date":"2023-07-14","current":-0.941755,"twenty":-3.569747,"median":-1.886392,"eighty":-1.053985,"marketCap":12882267},{"date":"2023-07-21","current":-1.163287,"twenty":-3.502605,"median":-1.869469,"eighty":-1.049467,"marketCap":15912604},{"date":"2023-07-28","current":-1.204275,"twenty":-3.502605,"median":-1.836312,"eighty":-1.049467,"marketCap":16473283},{"date":"2023-08-04","current":-1.17207,"twenty":-3.403434,"median":-1.830588,"eighty":-1.050276,"marketCap":16032749},{"date":"2023-08-11","current":-1.050081,"twenty":-3.40315,"median":-1.814802,"eighty":-1.050276,"marketCap":14364062},{"date":"2023-08-18","current":-0.564163,"twenty":-3.3907,"median":-1.811471,"eighty":-1.049467,"marketCap":12787321},{"date":"2023-08-25","current":-0.552699,"twenty":-3.377958,"median":-1.798653,"eighty":-1.034564,"marketCap":12527472},{"date":"2023-09-01","current":-0.52253,"twenty":-3.322712,"median":-1.778373,"eighty":-1.033491,"marketCap":11843658},{"date":"2023-09-08","current":-0.513479,"twenty":-3.263311,"median":-1.770105,"eighty":-1.029914,"marketCap":11638514},{"date":"2023-09-15","current":-0.488137,"twenty":-3.240922,"median":-1.761356,"eighty":-1.013293,"marketCap":11064110},{"date":"2023-09-22","current":-0.517703,"twenty":-3.21713,"median":-1.75358,"eighty":-0.999188,"marketCap":11734248},{"date":"2023-09-29","current":-0.528564,"twenty":-3.210163,"median":-1.74386,"eighty":-0.98232,"marketCap":11980421},{"date":"2023-10-06","current":-0.515892,"twenty":-3.170308,"median":-1.731979,"eighty":-0.976461,"marketCap":11693219},{"date":"2023-10-13","current":-0.40125,"twenty":-3.078182,"median":-1.721224,"eighty":-0.974416,"marketCap":9094726},{"date":"2023-10-20","current":-0.276349,"twenty":-3.032863,"median":-1.709885,"eighty":-0.960388,"marketCap":6263736},{"date":"2023-10-27","current":-0.216614,"twenty":-3.031897,"median":-1.706706,"eighty":-0.958209,"marketCap":4909784},{"date":"2023-11-03","current":-0.295428,"twenty":-2.987845,"median":-1.685616,"eighty":-0.953765,"marketCap":6696180},{"date":"2023-11-10","current":-0.261799,"twenty":-2.970163,"median":-1.678137,"eighty":-0.940518,"marketCap":5933925},{"date":"2023-11-17","current":-0.217526,"twenty":-2.954274,"median":-1.668413,"eighty":-0.932386,"marketCap":5751810},{"date":"2023-11-24","current":-0.183663,"twenty":-2.953963,"median":-1.661099,"eighty":-0.922912,"marketCap":4856409},{"date":"2023-12-01","current":-0.192054,"twenty":-2.951944,"median":-1.645109,"eighty":-0.917162,"marketCap":5078286},{"date":"2023-12-08","current":-0.190837,"twenty":-2.944758,"median":-1.621837,"eighty":-0.911584,"marketCap":5046113},{"date":"2023-12-15","current":-0.175054,"twenty":-2.928328,"median":-1.61464,"eighty":-0.907362,"marketCap":4628765},{"date":"2023-12-22","current":-0.185385,"twenty":-2.91294,"median":-1.600191,"eighty":-0.900572,"marketCap":4901938},{"date":"2023-12-29","current":-0.163575,"twenty":-2.907091,"median":-1.589608,"eighty":-0.885033,"marketCap":4325239},{"date":"2024-01-05","current":-0.175054,"twenty":-2.902704,"median":-1.572154,"eighty":-0.867134,"marketCap":4628765},{"date":"2024-01-12","current":-0.131434,"twenty":-2.866146,"median":-1.516751,"eighty":-0.850799,"marketCap":3475368},{"date":"2024-01-19","current":-0.10389,"twenty":-2.854448,"median":-1.410777,"eighty":-0.829681,"marketCap":2747058},{"date":"2024-01-26","current":-0.084944,"twenty":-2.8442,"median":-1.402772,"eighty":-0.799999,"marketCap":2246089},{"date":"2024-02-02","current":-0.085053,"twenty":-2.779613,"median":-1.384283,"eighty":-0.620519,"marketCap":2248978},{"date":"2024-02-09","current":-0.070927,"twenty":-2.71595,"median":-1.37766,"eighty":-0.554991,"marketCap":1875445},{"date":"2024-02-16","current":-0.067492,"twenty":-2.693326,"median":-1.371037,"eighty":-0.547268,"marketCap":1784632},{"date":"2024-02-23","current":-0.096807,"twenty":-2.67312,"median":-1.360871,"eighty":-0.530494,"marketCap":2559764},{"date":"2024-03-01","current":-0.161236,"twenty":-2.649818,"median":-1.31805,"eighty":-0.527538,"marketCap":4263401},{"date":"2024-03-08","current":-0.229045,"twenty":-2.634657,"median":-1.292619,"eighty":-0.52253,"marketCap":6056401},{"date":"2024-03-15","current":-0.33683,"twenty":-2.626801,"median":-1.272589,"eighty":-0.518306,"marketCap":8906472},{"date":"2024-03-22","current":-0.316018,"twenty":-2.602928,"median":-1.245193,"eighty":-0.51541,"marketCap":6361766},{"date":"2024-03-28","current":-0.290737,"twenty":-2.582456,"median":-1.231946,"eighty":-0.513117,"marketCap":5852824},{"date":"2024-04-05","current":-0.429785,"twenty":-2.570757,"median":-1.221642,"eighty":-0.500804,"marketCap":8652002},{"date":"2024-04-12","current":-0.505629,"twenty":-2.563446,"median":-1.213732,"eighty":-0.500665,"marketCap":10178826},{"date":"2024-04-19","current":-0.422201,"twenty":-2.550285,"median":-1.201552,"eighty":-0.498515,"marketCap":8499319},{"date":"2024-04-26","current":-0.427257,"twenty":-2.525426,"median":-1.191588,"eighty":-0.460964,"marketCap":8601107},{"date":"2024-05-03","current":-0.452538,"twenty":-2.496179,"median":-1.178959,"eighty":-0.457095,"marketCap":9110049},{"date":"2024-05-10","current":-0.399447,"twenty":-2.475707,"median":-1.173046,"eighty":-0.438396,"marketCap":8041272},{"date":"2024-05-17","current":-0.240254,"twenty":-2.462546,"median":-1.171094,"eighty":-0.430796,"marketCap":5547460},{"date":"2024-05-24","current":-0.233641,"twenty":-2.44646,"median":-1.163287,"eighty":-0.420684,"marketCap":5394777},{"date":"2024-05-31","current":-0.22262,"twenty":-2.440611,"median":-1.153528,"eighty":-0.404698,"marketCap":5140307},{"date":"2024-06-07","current":-0.224825,"twenty":-2.431837,"median":-1.150713,"eighty":-0.39338,"marketCap":5191201},{"date":"2024-06-14","current":-0.218212,"twenty":-2.420138,"median":-1.143223,"eighty":-0.377958,"marketCap":5038518},{"date":"2024-06-21","current":-0.227029,"twenty":-2.414289,"median":-1.132815,"eighty":-0.32637,"marketCap":5242095},{"date":"2024-06-28","current":-0.198375,"twenty":-2.404053,"median":-1.132098,"eighty":-0.322086,"marketCap":4580476},{"date":"2024-07-05","current":-0.182946,"twenty":-2.368957,"median":-1.122474,"eighty":-0.316018,"marketCap":4224212},{"date":"2024-07-12","current":-0.242458,"twenty":-2.354334,"median":-1.113348,"eighty":-0.298321,"marketCap":5598354},{"date":"2024-07-15","current":-0.232539,"twenty":-2.349947,"median":-1.113348,"eighty":-0.298028,"marketCap":5369330},{"date":"2024-08-02","current":-0.249115,"twenty":-2.34556,"median":-1.113348,"eighty":-0.296658,"marketCap":5752054},{"date":"2024-08-09","current":-0.27552,"twenty":-2.314851,"median":-1.110193,"eighty":-0.291016,"marketCap":6361766},{"date":"2024-08-16","current":-0.436989,"twenty":-2.281143,"median":-1.104222,"eighty":-0.282675,"marketCap":5903719},{"date":"2024-08-23","current":-0.512909,"twenty":-2.269285,"median":-1.095096,"eighty":-0.285652,"marketCap":6929397},{"date":"2024-08-30","current":-0.453411,"twenty":-2.268119,"median":-1.086232,"eighty":-0.289542,"marketCap":6125587},{"date":"2024-09-06","current":-0.459566,"twenty":-2.268119,"median":-1.085971,"eighty":-0.290876,"marketCap":6208740},{"date":"2024-09-13","current":-0.504702,"twenty":-2.268119,"median":-1.077379,"eighty":-0.291915,"marketCap":6818527},{"date":"2024-09-20","current":-0.525219,"twenty":-2.26489,"median":-1.063156,"eighty":-0.294158,"marketCap":7095703},{"date":"2024-09-27","current":-0.517012,"twenty":-2.2515,"median":-1.058593,"eighty":-0.295501,"marketCap":6984832},{"date":"2024-10-04","current":-0.475979,"twenty":-2.248992,"median":-1.053985,"eighty":-0.296225,"marketCap":6430480},{"date":"2024-10-11","current":-0.289691,"twenty":-2.243222,"median":-1.050178,"eighty":-0.296225,"marketCap":3913723},{"date":"2024-10-18","current":-0.308156,"twenty":-2.229013,"median":-1.049467,"eighty":-0.298028,"marketCap":4163182},{"date":"2024-10-25","current":-0.398017,"twenty":-2.224479,"median":-1.040342,"eighty":-0.298321,"marketCap":5377212},{"date":"2024-10-31","current":-0.383204,"twenty":-2.222725,"median":-1.037453,"eighty":-0.298321,"marketCap":5177091},{"date":"2024-11-08","current":-0.361088,"twenty":-2.215414,"median":-1.034564,"eighty":-0.303378,"marketCap":4878295},{"date":"2024-11-15","current":-0.304447,"twenty":-2.215414,"median":-1.032353,"eighty":-0.304447,"marketCap":3908180},{"date":"2024-11-22","current":-0.327766,"twenty":-2.208102,"median":-1.031216,"eighty":-0.304447,"marketCap":4207530},{"date":"2024-11-29","current":-0.543296,"twenty":-2.204273,"median":-1.02209,"eighty":-0.307414,"marketCap":6974289},{"date":"2024-12-06","current":-0.609699,"twenty":-2.203316,"median":-1.01317,"eighty":-0.311077,"marketCap":7826703},{"date":"2024-12-13","current":-0.639882,"twenty":-2.186035,"median":-1.003838,"eighty":-0.313349,"marketCap":8214163},{"date":"2024-12-20","current":-0.615735,"twenty":-2.181715,"median":-0.990509,"eighty":-0.315561,"marketCap":7904195},{"date":"2024-12-27","current":-0.645918,"twenty":-2.18,"median":-0.984212,"eighty":-0.316224,"marketCap":8291655},{"date":"2025-01-03","current":-0.657992,"twenty":-2.175931,"median":-0.97836,"eighty":-0.316605,"marketCap":8446639},{"date":"2025-01-10","current":-0.712321,"twenty":-2.170082,"median":-0.976461,"eighty":-0.317285,"marketCap":9144068},{"date":"2025-01-17","current":-0.645918,"twenty":-2.164233,"median":-0.975912,"eighty":-0.318547,"marketCap":8291655},{"date":"2025-01-24","current":-0.651955,"twenty":-2.164233,"median":-0.973635,"eighty":-0.318547,"marketCap":8369147},{"date":"2025-01-31","current":-0.639882,"twenty":-2.160113,"median":-0.961163,"eighty":-0.321075,"marketCap":8214163},{"date":"2025-02-07","current":-0.700248,"twenty":-2.160113,"median":-0.958209,"eighty":-0.326131,"marketCap":8989084},{"date":"2025-02-14","current":-0.706285,"twenty":-2.159897,"median":-0.956813,"eighty":-0.32643,"marketCap":9066576},{"date":"2025-02-21","current":-0.694211,"twenty":-2.158342,"median":-0.950453,"eighty":-0.327499,"marketCap":8911592},{"date":"2025-02-28","current":-0.588993,"twenty":-2.157127,"median":-0.941755,"eighty":-0.328163,"marketCap":7560905},{"date":"2025-03-07","current":-0.539915,"twenty":-2.156921,"median":-0.936875,"eighty":-0.331147,"marketCap":6930894},{"date":"2025-03-14","current":-0.567442,"twenty":-2.149021,"median":-0.932386,"eighty":-0.33522,"marketCap":7284258},{"date":"2025-03-21","current":-0.621772,"twenty":-2.144367,"median":-0.925242,"eighty":-0.336386,"marketCap":7981687},{"date":"2025-03-28","current":-0.423584,"twenty":-2.142578,"median":-0.921706,"eighty":-0.336726,"marketCap":7522432},{"date":"2025-04-04","current":-0.393453,"twenty":-2.139269,"median":-0.916869,"eighty":-0.336822,"marketCap":6987334},{"date":"2025-04-11","current":-0.404246,"twenty":-2.138339,"median":-0.91258,"eighty":-0.336822,"marketCap":7179010},{"date":"2025-04-17","current":-0.417238,"twenty":-2.138166,"median":-0.907598,"eighty":-0.339174,"marketCap":7409733},{"date":"2025-04-25","current":-0.41424,"twenty":-2.125638,"median":-0.9075,"eighty":-0.3414,"marketCap":7356489},{"date":"2025-05-02","current":-0.344834,"twenty":-2.110345,"median":-0.906232,"eighty":-0.343542,"marketCap":6123909},{"date":"2025-05-09","current":-0.363472,"twenty":-2.099513,"median":-0.900279,"eighty":-0.34477,"marketCap":6454898},{"date":"2025-05-16","current":-0.349755,"twenty":-2.088996,"median":-0.883001,"eighty":-0.34477,"marketCap":6211299},{"date":"2025-05-23","current":-0.514188,"twenty":-2.084725,"median":-0.866384,"eighty":-0.346273,"marketCap":5926011},{"date":"2025-05-30","current":-0.469837,"twenty":-2.081432,"median":-0.858803,"eighty":-0.348052,"marketCap":5414873},{"date":"2025-06-06","current":-0.491366,"twenty":-2.073569,"median":-0.842312,"eighty":-0.349471,"marketCap":5662995},{"date":"2025-06-13","current":-0.532757,"twenty":-2.0665,"median":-0.829622,"eighty":-0.349765,"marketCap":6140028},{"date":"2025-06-20","current":-0.532675,"twenty":-2.060618,"median":-0.825469,"eighty":-0.349781,"marketCap":6139083},{"date":"2025-06-27","current":-0.512185,"twenty":-2.052928,"median":-0.799785,"eighty":-0.349951,"marketCap":5902928},{"date":"2025-07-03","current":-0.573739,"twenty":-2.05189,"median":-0.78639,"eighty":-0.35063,"marketCap":6612337},{"date":"2025-07-11","current":-0.695043,"twenty":-2.046923,"median":-0.71534,"eighty":-0.351281,"marketCap":8010375},{"date":"2025-07-18","current":-0.697502,"twenty":-2.041307,"median":-0.706285,"eighty":-0.356276,"marketCap":8038713},{"date":"2025-07-25","current":-0.905687,"twenty":-2.039935,"median":-0.712329,"eighty":-0.356574,"marketCap":10438047},{"date":"2025-08-01","current":-0.885197,"twenty":-2.030507,"median":-0.718358,"eighty":-0.359175,"marketCap":10201892},{"date":"2025-08-08","current":-0.835717,"twenty":-2.008905,"median":-0.762437,"eighty":-0.359446,"marketCap":9631638},{"date":"2025-08-15","current":-0.621125,"twenty":-2.003377,"median":-0.78639,"eighty":-0.359774,"marketCap":10305714},{"date":"2025-08-22","current":-0.563064,"twenty":-1.997241,"median":-0.720716,"eighty":-0.359774,"marketCap":9342354},{"date":"2025-08-29","current":-0.547503,"twenty":-1.992921,"median":-0.712337,"eighty":-0.361088,"marketCap":9084178},{"date":"2025-09-05","current":-0.539402,"twenty":-1.992575,"median":-0.712321,"eighty":-0.362007,"marketCap":8949755},{"date":"2025-09-12","current":-0.535608,"twenty":-1.991884,"median":-0.704879,"eighty":-0.363225,"marketCap":8886812},{"date":"2025-09-19","current":-0.555219,"twenty":-1.98819,"median":-0.697502,"eighty":-0.364471,"marketCap":9212199},{"date":"2025-09-26","current":-0.617332,"twenty":-1.984194,"median":-0.694211,"eighty":-0.365097,"marketCap":10242771},{"date":"2025-10-03","current":-0.668707,"twenty":-1.980651,"median":-0.694211,"eighty":-0.365292,"marketCap":11095179},{"date":"2025-10-10","current":-0.668642,"twenty":-1.974776,"median":-0.691307,"eighty":-0.368878,"marketCap":11094112},{"date":"2025-10-17","current":-0.636557,"twenty":-1.962302,"median":-0.685372,"eighty":-0.371766,"marketCap":10561757},{"date":"2025-10-24","current":-0.726575,"twenty":-1.949718,"median":-0.682138,"eighty":-0.372384,"marketCap":12055339},{"date":"2025-10-31","current":-0.687996,"twenty":-1.944736,"median":-0.682138,"eighty":-0.372708,"marketCap":11415232},{"date":"2025-11-07","current":-0.745865,"twenty":-1.944102,"median":-0.683755,"eighty":-0.374768,"marketCap":12375392},{"date":"2025-11-14","current":-0.572323,"twenty":-1.944102,"median":-0.682138,"eighty":-0.377419,"marketCap":9495980},{"date":"2025-11-21","current":-0.499555,"twenty":-1.944102,"median":-0.681566,"eighty":-0.382155,"marketCap":8778176},{"date":"2025-11-28","current":-0.541516,"twenty":-1.943972,"median":-0.678834,"eighty":-0.385149,"marketCap":9515515},{"date":"2025-12-05","current":-0.549139,"twenty":-1.931185,"median":-0.676102,"eighty":-0.386667,"marketCap":9649470},{"date":"2025-12-12","current":-0.538864,"twenty":-1.922587,"median":-0.670065,"eighty":-0.388327,"marketCap":9468921},{"date":"2025-12-19","current":-0.504129,"twenty":-1.922371,"median":-0.670065,"eighty":-0.389335,"marketCap":8858549},{"date":"2025-12-26","current":-0.477282,"twenty":-1.921507,"median":-0.670065,"eighty":-0.390001,"marketCap":8386792},{"date":"2026-01-02","current":-0.377848,"twenty":-1.917779,"median":-0.668707,"eighty":-0.389668,"marketCap":6639544},{"date":"2026-01-09","current":-0.545493,"twenty":-1.907529,"median":-0.668513,"eighty":-0.391173,"marketCap":9585404},{"date":"2026-01-16","current":-0.553514,"twenty":-1.907006,"median":-0.664028,"eighty":-0.392181,"marketCap":9726349},{"date":"2026-01-23","current":-0.662891,"twenty":-1.904912,"median":-0.664028,"eighty":-0.393453,"marketCap":11648323},{"date":"2026-01-30","current":-0.653611,"twenty":-1.904356,"median":-0.662584,"eighty":-0.393914,"marketCap":11485246},{"date":"2026-02-06","current":-0.555436,"twenty":-1.901116,"median":-0.661565,"eighty":-0.395966,"marketCap":9760129},{"date":"2026-02-13","current":-0.523684,"twenty":-1.900906,"median":-0.657992,"eighty":-0.397301,"marketCap":9202175},{"date":"2026-02-20","current":-0.57002,"twenty":-1.900906,"median":-0.657992,"eighty":-0.397874,"marketCap":10016392},{"date":"2026-02-27","current":-0.614367,"twenty":-1.900901,"median":-0.653611,"eighty":-0.399003,"marketCap":10795665},{"date":"2026-03-06","current":-0.571942,"twenty":-1.889596,"median":-0.650794,"eighty":-0.399407,"marketCap":10050173},{"date":"2026-03-13","current":-0.576715,"twenty":-1.886468,"median":-0.649417,"eighty":-0.399689,"marketCap":10134041},{"date":"2026-03-20","current":-0.945929,"twenty":-1.880545,"median":-0.647668,"eighty":-0.400149,"marketCap":9966305},{"date":"2026-03-27","current":-0.895293,"twenty":-1.879081,"median":-0.649417,"eighty":-0.400249,"marketCap":9432811},{"date":"2026-04-02","current":-1.018123,"twenty":-1.867547,"median":-0.649417,"eighty":-0.40085,"marketCap":10726940},{"date":"2026-04-10","current":-1.149796,"twenty":-1.848792,"median":-0.652451,"eighty":-0.401255,"marketCap":12114255},{"date":"2026-04-17","current":-1.194019,"twenty":-1.838353,"median":-0.655847,"eighty":-0.401689,"marketCap":12580188},{"date":"2026-04-24","current":-1.138741,"twenty":-1.836182,"median":-0.657992,"eighty":-0.403338,"marketCap":11997772},{"date":"2026-05-01","current":-1.194019,"twenty":-1.835837,"median":-0.659062,"eighty":-0.404396,"marketCap":12580188},{"date":"2026-05-08","current":-1.260354,"twenty":-1.829573,"median":-0.662253,"eighty":-0.404501,"marketCap":13279088},{"date":"2026-05-15","current":-1.126677,"twenty":-1.82306,"median":-0.662891,"eighty":-0.404649,"marketCap":11870671},{"date":"2026-05-22","current":-0.84405,"twenty":-1.817452,"median":-0.664028,"eighty":-0.405182,"marketCap":9356289},{"date":"2026-05-29","current":-0.931574,"twenty":-1.814802,"median":-0.666206,"eighty":-0.405782,"marketCap":10326499},{"date":"2026-06-05","current":-1.07781,"twenty":-1.814192,"median":-0.668707,"eighty":-0.407878,"marketCap":11947520},{"date":"2026-06-12","current":-0.960063,"twenty":-1.811832,"median":-0.669386,"eighty":-0.411892,"marketCap":10642298},{"date":"2026-06-18","current":-1.062644,"twenty":-1.809666,"median":-0.670065,"eighty":-0.414315,"marketCap":11779414},{"date":"2026-06-26","current":-1.093337,"twenty":-1.807463,"median":-0.670065,"eighty":-0.41514,"marketCap":12119645},{"date":"2026-07-02","current":-1.166565,"twenty":-1.798653,"median":-0.672176,"eighty":-0.417238,"marketCap":12931377},{"date":"2026-07-10","current":-1.316717,"twenty":-1.791524,"median":-0.676102,"eighty":-0.417238,"marketCap":14595812},{"date":"2026-07-17","current":-1.282067,"twenty":-1.781685,"median":-0.681566,"eighty":-0.418534,"marketCap":14211711},{"date":"2026-07-24","current":-1.258967,"twenty":-1.775062,"median":-0.682138,"eighty":-0.419237,"marketCap":13955644},{"date":"2026-07-31","current":-1.420669,"twenty":-1.771183,"median":-0.683755,"eighty":-0.419585,"marketCap":15748113},{"date":"2026-08-07","current":-1.443769,"twenty":-1.77004,"median":-0.687996,"eighty":-0.419724,"marketCap":16004180},{"date":"2026-08-14","current":-1.455319,"twenty":-1.763675,"median":-0.694211,"eighty":-0.421708,"marketCap":16132213},{"date":"2026-08-21","current":-3.453494,"twenty":-1.783653,"median":-0.694211,"eighty":-0.423307,"marketCap":21981491},{"date":"2026-08-28","current":-3.476829,"twenty":-1.810388,"median":-0.694319,"eighty":-0.424503,"marketCap":22130014},{"date":"2026-09-04","current":-3.523498,"twenty":-1.822243,"median":-0.697502,"eighty":-0.426752,"marketCap":22427062},{"date":"2026-09-11","current":-3.406825,"twenty":-1.836182,"median":-0.700856,"eighty":-0.427257,"marketCap":21684444},{"date":"2026-09-14","current":-3.616835,"twenty":-1.837333,"median":-0.702867,"eighty":-0.427257,"marketCap":23021156}],"updateTime":1789515530521},"$inf$@#url:\"https://stock-news.skytigris.cn/v3/notice/important/events/list\",params:#symbol:\"BFRI\",pageSize:20,pageCount:10,market:\"us\",,,undefined,":[{"items":[{"cdn_pdf":false,"hasAttachments":true,"id":"13675986","market":"us","labels":[],"media":"sec.gov","original_id":"AN149315221025646-BFRI","pdf_url":"","pub_time":1634486400000,"showTitleType":true,"size":0,"source":"sec_us","summary":"CORRESP [Cover] - Correspondence","symbol":"BFRI","title":"CORRESP [Cover] - Correspondence","titleType":"SEC問詢函","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221025646/0001493152-21-025646-index.htm","us_notice_code":"Form CORRESP","us_title_en":"CORRESP [Cover] - Correspondence","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221025646/filename1.htm","primary":true,"translateUrl":"","linkName":"filename1.htm","type":"CORRESP","id":"NTFILEAm4VgCniHXWw7YZY","market":"us","size":13917}],"type_name":"交易披露","type_name_en":"Transaction Related","titleTypeEn":"Correspondence","us_type":"usAnnouncement","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"SEC問詢函","pubTime":"2021-10-18 00:00","pubTimestamp":1634486400,"title_zh":"CORRESP [Cover] - Correspondence","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"13675988","market":"us","labels":[],"media":"sec.gov","original_id":"AN149315221025483-BFRI","pdf_url":"","pub_time":1634227200000,"showTitleType":true,"size":0,"source":"sec_us","summary":"S-1/A [Amend]  - General form for registration of securities under the Securities Act of 1933","symbol":"BFRI","title":"S-1/A [Amend]  - General form for registration of securities under the Securities Act of 1933","titleType":"[修訂]招股説明書","type":"usProspectusesRegistrations","url":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221025483/0001493152-21-025483-index.htm","us_notice_code":"Form S-1/A","us_title_en":"S-1/A [Amend]  - General form for registration of securities under the Securities Act of 1933","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221025483/forms-1a.htm","primary":true,"translateUrl":"","linkName":"forms-1a.htm","type":"S-1/A","id":"NTFILE4jPFDyS1Uvbmwnbj","market":"us","size":2607257},{"description":"","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221025483/ex23-1.htm","primary":false,"translateUrl":"","linkName":"ex23-1.htm","type":"EX-23.1","id":"NTFILEGpsnQUUVJA3bSKY2","market":"us","size":3902},{"description":"","seq":3,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221025483/forms-1_001.jpg","primary":false,"translateUrl":"","linkName":"forms-1_001.jpg","type":"GRAPHIC","id":"NTFILEC6F9HgCBRRNQu68x","market":"us","size":83719},{"description":"","seq":4,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221025483/forms-1_1.jpg","primary":false,"translateUrl":"","linkName":"forms-1_1.jpg","type":"GRAPHIC","id":"NTFILEH7fqdxnkGxjiKaw9","market":"us","size":13530},{"description":"","seq":5,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221025483/forms-1a_002.jpg","primary":false,"translateUrl":"","linkName":"forms-1a_002.jpg","type":"GRAPHIC","id":"NTFILEF4sqPE9iQrnRSdPs","market":"us","size":9770},{"description":"","seq":6,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221025483/forms-1a_003.jpg","primary":false,"translateUrl":"","linkName":"forms-1a_003.jpg","type":"GRAPHIC","id":"NTFILECNx3aQvVBezTojjU","market":"us","size":12163},{"description":"","seq":7,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221025483/forms-1a_004.jpg","primary":false,"translateUrl":"","linkName":"forms-1a_004.jpg","type":"GRAPHIC","id":"NTFILE7PUsHH7DzzCSwDX9","market":"us","size":52065},{"description":"","seq":8,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221025483/forms-1a_005.jpg","primary":false,"translateUrl":"","linkName":"forms-1a_005.jpg","type":"GRAPHIC","id":"NTFILEAei6gYff2jiU6SQR","market":"us","size":83719}],"type_name":"招股註冊","type_name_en":"Recruitment Registration","titleTypeEn":"[Amend]Public Prospectus","us_type":"usProspectusesRegistrations","us_type_zh":"招股註冊","earn_infos":[],"event_type":"important_notice","event_name":"[修訂]招股説明書","pubTime":"2021-10-15 00:00","pubTimestamp":1634227200,"title_zh":"S-1/A [Amend]  - General form for registration of securities under the Securities Act of 1933","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"13675991","market":"us","labels":[],"media":"sec.gov","original_id":"AN149315221025361-BFRI","pdf_url":"","pub_time":1634140800000,"showTitleType":true,"size":0,"source":"sec_us","summary":"S-1/A [Amend]  - General form for registration of securities under the Securities Act of 1933","symbol":"BFRI","title":"S-1/A [Amend]  - General form for registration of securities under the Securities Act of 1933","titleType":"[修訂]招股説明書","type":"usProspectusesRegistrations","url":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221025361/0001493152-21-025361-index.htm","us_notice_code":"Form S-1/A","us_title_en":"S-1/A [Amend]  - General form for registration of securities under the Securities Act of 1933","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221025361/forms-1a.htm","primary":true,"translateUrl":"","linkName":"forms-1a.htm","type":"S-1/A","id":"NTFILE6YRrMqNq5CBqzPPN","market":"us","size":2595094},{"description":"","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221025361/forms-1_001.jpg","primary":false,"translateUrl":"","linkName":"forms-1_001.jpg","type":"GRAPHIC","id":"NTFILECSjdHkHAGmXQ2xXY","market":"us","size":83719},{"description":"","seq":3,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221025361/forms-1_1.jpg","primary":false,"translateUrl":"","linkName":"forms-1_1.jpg","type":"GRAPHIC","id":"NTFILEKydhxH3wq4NJjiB5","market":"us","size":13530},{"description":"","seq":4,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221025361/forms-1a_002.jpg","primary":false,"translateUrl":"","linkName":"forms-1a_002.jpg","type":"GRAPHIC","id":"NTFILE9LiCMrA73Mx87ZVx","market":"us","size":9770},{"description":"","seq":5,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221025361/forms-1a_003.jpg","primary":false,"translateUrl":"","linkName":"forms-1a_003.jpg","type":"GRAPHIC","id":"NTFILE6psghPgZJqk4WuMp","market":"us","size":12163},{"description":"","seq":6,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221025361/forms-1a_004.jpg","primary":false,"translateUrl":"","linkName":"forms-1a_004.jpg","type":"GRAPHIC","id":"NTFILEJ87HiqseWeBjNRj7","market":"us","size":52065},{"description":"","seq":7,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221025361/forms-1a_005.jpg","primary":false,"translateUrl":"","linkName":"forms-1a_005.jpg","type":"GRAPHIC","id":"NTFILEA5wUzcrF1vq41CKG","market":"us","size":83719}],"type_name":"招股註冊","type_name_en":"Recruitment Registration","titleTypeEn":"[Amend]Public Prospectus","us_type":"usProspectusesRegistrations","us_type_zh":"招股註冊","earn_infos":[],"event_type":"important_notice","event_name":"[修訂]招股説明書","pubTime":"2021-10-14 00:00","pubTimestamp":1634140800,"title_zh":"S-1/A [Amend]  - General form for registration of securities under the Securities Act of 1933","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"13675989","market":"us","labels":[],"media":"sec.gov","original_id":"AN149315221025485-BFRI","pdf_url":"","pub_time":1634140800000,"showTitleType":true,"size":0,"source":"sec_us","summary":"CORRESP [Cover] - Correspondence","symbol":"BFRI","title":"CORRESP [Cover] - Correspondence","titleType":"SEC問詢函","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221025485/0001493152-21-025485-index.htm","us_notice_code":"Form CORRESP","us_title_en":"CORRESP [Cover] - Correspondence","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221025485/filename1.htm","primary":true,"translateUrl":"","linkName":"filename1.htm","type":"CORRESP","id":"NTFILE8NLLbdLbpeE3pyKo","market":"us","size":23827},{"description":"","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221025485/formcorresp_001.jpg","primary":false,"translateUrl":"","linkName":"formcorresp_001.jpg","type":"GRAPHIC","id":"NTFILEUzKmGsL3b6KeYGA4","market":"us","size":5974}],"type_name":"交易披露","type_name_en":"Transaction Related","titleTypeEn":"Correspondence","us_type":"usAnnouncement","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"SEC問詢函","pubTime":"2021-10-14 00:00","pubTimestamp":1634140800,"title_zh":"CORRESP [Cover] - Correspondence","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"13975579","market":"us","labels":[],"media":"sec.gov","original_id":"AN149315221025256-BFRI","pdf_url":"","pub_time":1634054400000,"showTitleType":true,"size":0,"source":"sec_us","summary":"S-1/A [Amend]  - General form for registration of securities under the Securities Act of 1933","symbol":"BFRI","title":"S-1/A [Amend]  - General form for registration of securities under the Securities Act of 1933","titleType":"[修訂]招股説明書","type":"usProspectusesRegistrations","url":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221025256/0001493152-21-025256-index.htm","us_notice_code":"Form S-1/A","us_title_en":"S-1/A [Amend]  - General form for registration of securities under the Securities Act of 1933","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221025256/forms-1a.htm","primary":true,"translateUrl":"","linkName":"forms-1a.htm","type":"S-1/A","id":"NTFILE96ow5sKp77qJ27me","market":"us","size":2587016},{"description":"","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221025256/ex10-17.htm","primary":false,"translateUrl":"","linkName":"ex10-17.htm","type":"EX-10.17","id":"NTFILEHATjpBsobsiYSQno","market":"us","size":46355},{"description":"","seq":3,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221025256/forms-1_001.jpg","primary":false,"translateUrl":"","linkName":"forms-1_001.jpg","type":"GRAPHIC","id":"NTFILE2mRhZR1eTPv6FusE","market":"us","size":83719},{"description":"","seq":4,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221025256/forms-1_1.jpg","primary":false,"translateUrl":"","linkName":"forms-1_1.jpg","type":"GRAPHIC","id":"NTFILEi5AuQEpKSjNNUYtF","market":"us","size":13530},{"description":"","seq":5,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221025256/forms-1a_002.jpg","primary":false,"translateUrl":"","linkName":"forms-1a_002.jpg","type":"GRAPHIC","id":"NTFILEQ6C2YJvbv9nc2MDA","market":"us","size":9770},{"description":"","seq":6,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221025256/forms-1a_003.jpg","primary":false,"translateUrl":"","linkName":"forms-1a_003.jpg","type":"GRAPHIC","id":"NTFILEDAVXDwHeg6vNqfKx","market":"us","size":12163},{"description":"","seq":7,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221025256/forms-1a_004.jpg","primary":false,"translateUrl":"","linkName":"forms-1a_004.jpg","type":"GRAPHIC","id":"NTFILEESgfuYiiV3cY4u2X","market":"us","size":52065},{"description":"","seq":8,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221025256/forms-1a_005.jpg","primary":false,"translateUrl":"","linkName":"forms-1a_005.jpg","type":"GRAPHIC","id":"NTFILEEC5aSU1c2Qxr6sTp","market":"us","size":83719}],"type_name":"招股註冊","type_name_en":"Recruitment Registration","titleTypeEn":"[Amend]Public Prospectus","us_type":"usProspectusesRegistrations","us_type_zh":"招股註冊","earn_infos":[],"event_type":"important_notice","event_name":"[修訂]招股説明書","pubTime":"2021-10-13 00:00","pubTimestamp":1634054400,"title_zh":"S-1/A [Amend]  - General form for registration of securities under the Securities Act of 1933","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"13975578","market":"us","labels":[],"media":"sec.gov","original_id":"AN149315221025261-BFRI","pdf_url":"","pub_time":1634054400000,"showTitleType":true,"size":0,"source":"sec_us","summary":"CORRESP [Cover] - Correspondence","symbol":"BFRI","title":"CORRESP [Cover] - Correspondence","titleType":"SEC問詢函","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221025261/0001493152-21-025261-index.htm","us_notice_code":"Form CORRESP","us_title_en":"CORRESP [Cover] - Correspondence","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221025261/filename1.htm","primary":true,"translateUrl":"","linkName":"filename1.htm","type":"CORRESP","id":"NTFILEBWhVuCeHMw7dvgif","market":"us","size":24977},{"description":"","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221025261/corresp_001.jpg","primary":false,"translateUrl":"","linkName":"corresp_001.jpg","type":"GRAPHIC","id":"NTFILEHr2wWSgqknxPGcGk","market":"us","size":6004}],"type_name":"交易披露","type_name_en":"Transaction Related","titleTypeEn":"Correspondence","us_type":"usAnnouncement","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"SEC問詢函","pubTime":"2021-10-13 00:00","pubTimestamp":1634054400,"title_zh":"CORRESP [Cover] - Correspondence","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"13675993","market":"us","labels":[],"media":"sec.gov","original_id":"AN149315221025262-BFRI","pdf_url":"","pub_time":1634054400000,"showTitleType":true,"size":0,"source":"sec_us","summary":"CORRESP [Cover] - Correspondence","symbol":"BFRI","title":"CORRESP [Cover] - Correspondence","titleType":"SEC問詢函","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221025262/0001493152-21-025262-index.htm","us_notice_code":"Form CORRESP","us_title_en":"CORRESP [Cover] - Correspondence","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221025262/filename1.htm","primary":true,"translateUrl":"","linkName":"filename1.htm","type":"CORRESP","id":"NTFILE6VirmguWecDRxM5L","market":"us","size":16144},{"description":"","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221025262/corresp_001.jpg","primary":false,"translateUrl":"","linkName":"corresp_001.jpg","type":"GRAPHIC","id":"NTFILEAz1t6zjRYHu2j7WZ","market":"us","size":8361}],"type_name":"交易披露","type_name_en":"Transaction Related","titleTypeEn":"Correspondence","us_type":"usAnnouncement","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"SEC問詢函","pubTime":"2021-10-13 00:00","pubTimestamp":1634054400,"title_zh":"CORRESP [Cover] - Correspondence","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"13675992","market":"us","labels":[],"media":"sec.gov","original_id":"AN149315221025265-BFRI","pdf_url":"","pub_time":1634054400000,"showTitleType":true,"size":0,"source":"sec_us","summary":"CORRESP [Cover] - Correspondence","symbol":"BFRI","title":"CORRESP [Cover] - Correspondence","titleType":"SEC問詢函","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221025265/0001493152-21-025265-index.htm","us_notice_code":"Form CORRESP","us_title_en":"CORRESP [Cover] - Correspondence","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221025265/filename1.htm","primary":true,"translateUrl":"","linkName":"filename1.htm","type":"CORRESP","id":"NTFILEXKMLywtYLRffiNSa","market":"us","size":12378}],"type_name":"交易披露","type_name_en":"Transaction Related","titleTypeEn":"Correspondence","us_type":"usAnnouncement","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"SEC問詢函","pubTime":"2021-10-13 00:00","pubTimestamp":1634054400,"title_zh":"CORRESP [Cover] - Correspondence","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"13975581","market":"us","labels":[],"media":"sec.gov","original_id":"AN149315221025090-BFRI","pdf_url":"","pub_time":1633968000000,"showTitleType":true,"size":0,"source":"sec_us","summary":"S-1/A [Amend]  - General form for registration of securities under the Securities Act of 1933","symbol":"BFRI","title":"S-1/A [Amend]  - General form for registration of securities under the Securities Act of 1933","titleType":"[修訂]招股説明書","type":"usProspectusesRegistrations","url":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221025090/0001493152-21-025090-index.htm","us_notice_code":"Form S-1/A","us_title_en":"S-1/A [Amend]  - General form for registration of securities under the Securities Act of 1933","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221025090/forms-1a.htm","primary":true,"translateUrl":"","linkName":"forms-1a.htm","type":"S-1/A","id":"NTFILE4VkytK9JgSMfWjQF","market":"us","size":2579809},{"description":"","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221025090/ex1-1.htm","primary":false,"translateUrl":"","linkName":"ex1-1.htm","type":"EX-1.1","id":"NTFILEFm4WVAF2M3L6L5Fy","market":"us","size":300896},{"description":"","seq":3,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221025090/ex4-1.htm","primary":false,"translateUrl":"","linkName":"ex4-1.htm","type":"EX-4.1","id":"NTFILEDHYsDdUThorC3bBJ","market":"us","size":1706},{"description":"","seq":4,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221025090/ex10-12.htm","primary":false,"translateUrl":"","linkName":"ex10-12.htm","type":"EX-10.12","id":"NTFILEGMcXeBsY8xr2CMW9","market":"us","size":176604},{"description":"","seq":5,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221025090/ex10-13.htm","primary":false,"translateUrl":"","linkName":"ex10-13.htm","type":"EX-10.13","id":"NTFILE4JtTooeXtaZLG3Bt","market":"us","size":41578},{"description":"","seq":6,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221025090/ex10-14.htm","primary":false,"translateUrl":"","linkName":"ex10-14.htm","type":"EX-10.14","id":"NTFILEDE27gYLDnAkE9qpe","market":"us","size":45779},{"description":"","seq":7,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221025090/ex10-15.htm","primary":false,"translateUrl":"","linkName":"ex10-15.htm","type":"EX-10.15","id":"NTFILE79dWnxtiPe75uiYd","market":"us","size":45591},{"description":"","seq":8,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221025090/ex10-16.htm","primary":false,"translateUrl":"","linkName":"ex10-16.htm","type":"EX-10.16","id":"NTFILE9K2xrGVt3ZE87dsN","market":"us","size":80904},{"description":"","seq":9,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221025090/ex10-17.htm","primary":false,"translateUrl":"","linkName":"ex10-17.htm","type":"EX-10.17","id":"NTFILE3J59Rk3fHnmJa1Cz","market":"us","size":51825},{"description":"","seq":10,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221025090/ex23-1.htm","primary":false,"translateUrl":"","linkName":"ex23-1.htm","type":"EX-23.1","id":"NTFILEGCCZU22ujPXp8kyg","market":"us","size":3742},{"description":"","seq":11,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221025090/forms-1_001.jpg","primary":false,"translateUrl":"","linkName":"forms-1_001.jpg","type":"GRAPHIC","id":"NTFILE5g9kb5h8M6EkXE1Z","market":"us","size":83719},{"description":"","seq":12,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221025090/forms-1_1.jpg","primary":false,"translateUrl":"","linkName":"forms-1_1.jpg","type":"GRAPHIC","id":"NTFILE5QQRTLYSGGtjnMoY","market":"us","size":13530},{"description":"","seq":13,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221025090/forms-1a_002.jpg","primary":false,"translateUrl":"","linkName":"forms-1a_002.jpg","type":"GRAPHIC","id":"NTFILEGiXb3GTMwTBgQsUr","market":"us","size":9770},{"description":"","seq":14,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221025090/forms-1a_003.jpg","primary":false,"translateUrl":"","linkName":"forms-1a_003.jpg","type":"GRAPHIC","id":"NTFILECeEdAEw9cTQvq6tB","market":"us","size":12163},{"description":"","seq":15,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221025090/forms-1a_004.jpg","primary":false,"translateUrl":"","linkName":"forms-1a_004.jpg","type":"GRAPHIC","id":"NTFILENPnAsH8jzpPoUebL","market":"us","size":52065},{"description":"","seq":16,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221025090/forms-1a_005.jpg","primary":false,"translateUrl":"","linkName":"forms-1a_005.jpg","type":"GRAPHIC","id":"NTFILEBFwEPzkiJdq8Evp4","market":"us","size":83719},{"description":"","seq":17,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221025090/ex4-1_1.jpg","primary":false,"translateUrl":"","linkName":"ex4-1_1.jpg","type":"GRAPHIC","id":"NTFILE4c6K2KCRzoE5z6XM","market":"us","size":317639},{"description":"","seq":18,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221025090/ex4-1_2.jpg","primary":false,"translateUrl":"","linkName":"ex4-1_2.jpg","type":"GRAPHIC","id":"NTFILE3XuJ9Se2vYowMvLM","market":"us","size":194656}],"type_name":"招股註冊","type_name_en":"Recruitment Registration","titleTypeEn":"[Amend]Public Prospectus","us_type":"usProspectusesRegistrations","us_type_zh":"招股註冊","earn_infos":[],"event_type":"important_notice","event_name":"[修訂]招股説明書","pubTime":"2021-10-12 00:00","pubTimestamp":1633968000,"title_zh":"S-1/A [Amend]  - General form for registration of securities under the Securities Act of 1933","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"13975584","market":"us","labels":[],"media":"sec.gov","original_id":"AN149315221025092-BFRI","pdf_url":"","pub_time":1633622400000,"showTitleType":true,"size":0,"source":"sec_us","summary":"CORRESP [Cover] - Correspondence","symbol":"BFRI","title":"CORRESP [Cover] - Correspondence","titleType":"SEC問詢函","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221025092/0001493152-21-025092-index.htm","us_notice_code":"Form CORRESP","us_title_en":"CORRESP [Cover] - Correspondence","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221025092/filename1.htm","primary":true,"translateUrl":"","linkName":"filename1.htm","type":"CORRESP","id":"NTFILEENKGLknycvNLpJeg","market":"us","size":22669},{"description":"","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221025092/corresp_001.jpg","primary":false,"translateUrl":"","linkName":"corresp_001.jpg","type":"GRAPHIC","id":"NTFILE7w5FuZgodfaVf1kE","market":"us","size":6004}],"type_name":"交易披露","type_name_en":"Transaction Related","titleTypeEn":"Correspondence","us_type":"usAnnouncement","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"SEC問詢函","pubTime":"2021-10-08 00:00","pubTimestamp":1633622400,"title_zh":"CORRESP [Cover] - Correspondence","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"13975583","market":"us","labels":[],"media":"sec.gov","original_id":"AN149315221025095-BFRI","pdf_url":"","pub_time":1633622400000,"showTitleType":true,"size":0,"source":"sec_us","summary":"CORRESP [Cover] - Correspondence","symbol":"BFRI","title":"CORRESP [Cover] - Correspondence","titleType":"SEC問詢函","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221025095/0001493152-21-025095-index.htm","us_notice_code":"Form CORRESP","us_title_en":"CORRESP [Cover] - Correspondence","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221025095/filename1.htm","primary":true,"translateUrl":"","linkName":"filename1.htm","type":"CORRESP","id":"NTFILEAsspd3sgPfQqgTwR","market":"us","size":19945},{"description":"","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221025095/corresp_001.jpg","primary":false,"translateUrl":"","linkName":"corresp_001.jpg","type":"GRAPHIC","id":"NTFILEEW7rfaAiCXtiBVZ1","market":"us","size":6087}],"type_name":"交易披露","type_name_en":"Transaction Related","titleTypeEn":"Correspondence","us_type":"usAnnouncement","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"SEC問詢函","pubTime":"2021-10-08 00:00","pubTimestamp":1633622400,"title_zh":"CORRESP [Cover] - Correspondence","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"13975582","market":"us","labels":[],"media":"sec.gov","original_id":"AN149315221025096-BFRI","pdf_url":"","pub_time":1633622400000,"showTitleType":true,"size":0,"source":"sec_us","summary":"CORRESP [Cover] - Correspondence","symbol":"BFRI","title":"CORRESP [Cover] - Correspondence","titleType":"SEC問詢函","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221025096/0001493152-21-025096-index.htm","us_notice_code":"Form CORRESP","us_title_en":"CORRESP [Cover] - Correspondence","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221025096/filename1.htm","primary":true,"translateUrl":"","linkName":"filename1.htm","type":"CORRESP","id":"NTFILE7fdCfpaQ83Ef7H29","market":"us","size":13941}],"type_name":"交易披露","type_name_en":"Transaction Related","titleTypeEn":"Correspondence","us_type":"usAnnouncement","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"SEC問詢函","pubTime":"2021-10-08 00:00","pubTimestamp":1633622400,"title_zh":"CORRESP [Cover] - Correspondence","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"13975587","market":"us","labels":[],"media":"sec.gov","original_id":"AN149315221024281-BFRI","pdf_url":"","pub_time":1633017600000,"showTitleType":true,"size":0,"source":"sec_us","summary":"S-1/A [Amend]  - General form for registration of securities under the Securities Act of 1933","symbol":"BFRI","title":"S-1/A [Amend]  - General form for registration of securities under the Securities Act of 1933","titleType":"[修訂]招股説明書","type":"usProspectusesRegistrations","url":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221024281/0001493152-21-024281-index.htm","us_notice_code":"Form S-1/A","us_title_en":"S-1/A [Amend]  - General form for registration of securities under the Securities Act of 1933","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221024281/forms-1a.htm","primary":true,"translateUrl":"","linkName":"forms-1a.htm","type":"S-1/A","id":"NTFILE3LSY5EiN1Uw6rGXE","market":"us","size":2557925},{"description":"","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221024281/ex5-1.htm","primary":false,"translateUrl":"","linkName":"ex5-1.htm","type":"EX-5.1","id":"NTFILEHXeZSEFPWgzjVd5n","market":"us","size":35635},{"description":"","seq":3,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221024281/ex10-11.htm","primary":false,"translateUrl":"","linkName":"ex10-11.htm","type":"EX-10.11","id":"NTFILE82VeeBpVaVGoPqXp","market":"us","size":86161},{"description":"","seq":4,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221024281/ex23-1.htm","primary":false,"translateUrl":"","linkName":"ex23-1.htm","type":"EX-23.1","id":"NTFILE7nLxcjZ81c1RZ2y4","market":"us","size":3741},{"description":"","seq":5,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221024281/ex5-1_001.jpg","primary":false,"translateUrl":"","linkName":"ex5-1_001.jpg","type":"GRAPHIC","id":"NTFILE4LuuLadG7C5PEaFr","market":"us","size":2509},{"description":"","seq":6,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221024281/forms-1_001.jpg","primary":false,"translateUrl":"","linkName":"forms-1_001.jpg","type":"GRAPHIC","id":"NTFILE2tpabBSA2ULt15Rq","market":"us","size":83719},{"description":"","seq":7,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221024281/forms-1_1.jpg","primary":false,"translateUrl":"","linkName":"forms-1_1.jpg","type":"GRAPHIC","id":"NTFILE4qKXqeuG1qGfEJUk","market":"us","size":13530},{"description":"","seq":8,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221024281/forms-1a_002.jpg","primary":false,"translateUrl":"","linkName":"forms-1a_002.jpg","type":"GRAPHIC","id":"NTFILEBX5rK3TC4SCjofbx","market":"us","size":9770},{"description":"","seq":9,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221024281/forms-1a_003.jpg","primary":false,"translateUrl":"","linkName":"forms-1a_003.jpg","type":"GRAPHIC","id":"NTFILEAtVX5dWtqr9G2EAj","market":"us","size":12163},{"description":"","seq":10,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221024281/forms-1a_004.jpg","primary":false,"translateUrl":"","linkName":"forms-1a_004.jpg","type":"GRAPHIC","id":"NTFILE6iUVLYcqUwT1QT66","market":"us","size":52065},{"description":"","seq":11,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221024281/forms-1a_005.jpg","primary":false,"translateUrl":"","linkName":"forms-1a_005.jpg","type":"GRAPHIC","id":"NTFILE8o3MEVX3CmTxBrQd","market":"us","size":83719},{"description":"GRAPHIC","seq":12,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221024281/ex10-11_001.jpg","primary":false,"translateUrl":"","linkName":"ex10-11_001.jpg","type":"GRAPHIC","id":"NTFILE5ge9DLP3VF16tm2c","market":"us","size":2729}],"type_name":"招股註冊","type_name_en":"Recruitment Registration","titleTypeEn":"[Amend]Public Prospectus","us_type":"usProspectusesRegistrations","us_type_zh":"招股註冊","earn_infos":[],"event_type":"important_notice","event_name":"[修訂]招股説明書","pubTime":"2021-10-01 00:00","pubTimestamp":1633017600,"title_zh":"S-1/A [Amend]  - General form for registration of securities under the Securities Act of 1933","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"13975586","market":"us","labels":[],"media":"sec.gov","original_id":"AN149315221024369-BFRI","pdf_url":"","pub_time":1633017600000,"showTitleType":true,"size":0,"source":"sec_us","summary":"FWP  - Filing under Securities Act Rules 163/433 of free writing prospectuses","symbol":"BFRI","title":"FWP  - Filing under Securities Act Rules 163/433 of free writing prospectuses","titleType":"[補充]招股説明書","type":"usProspectusesRegistrations","url":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221024369/0001493152-21-024369-index.htm","us_notice_code":"Form FWP","us_title_en":"FWP  - Filing under Securities Act Rules 163/433 of free writing prospectuses","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221024369/fwp.htm","primary":true,"translateUrl":"","linkName":"fwp.htm","type":"FWP","id":"NTFILE6EHn1TUFe86CRyJY","market":"us","size":27195},{"description":"","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221024369/fwp_001.jpg","primary":false,"translateUrl":"","linkName":"fwp_001.jpg","type":"GRAPHIC","id":"NTFILEHuwhP8wJMh6B6pk8","market":"us","size":377044},{"description":"","seq":3,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221024369/fwp_002.jpg","primary":false,"translateUrl":"","linkName":"fwp_002.jpg","type":"GRAPHIC","id":"NTFILEBzirHVcGz7bLFYxA","market":"us","size":407383},{"description":"","seq":4,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221024369/fwp_003.jpg","primary":false,"translateUrl":"","linkName":"fwp_003.jpg","type":"GRAPHIC","id":"NTFILEApT1pcVK83GjJ48G","market":"us","size":374686},{"description":"","seq":5,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221024369/fwp_004.jpg","primary":false,"translateUrl":"","linkName":"fwp_004.jpg","type":"GRAPHIC","id":"NTFILE3XpesL21ZZWqpUzp","market":"us","size":304261},{"description":"","seq":6,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221024369/fwp_005.jpg","primary":false,"translateUrl":"","linkName":"fwp_005.jpg","type":"GRAPHIC","id":"NTFILE398hBwgem8mizwyY","market":"us","size":261444},{"description":"","seq":7,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221024369/fwp_006.jpg","primary":false,"translateUrl":"","linkName":"fwp_006.jpg","type":"GRAPHIC","id":"NTFILE2yWBEU71EjLrRxQK","market":"us","size":132267},{"description":"","seq":8,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221024369/fwp_007.jpg","primary":false,"translateUrl":"","linkName":"fwp_007.jpg","type":"GRAPHIC","id":"NTFILEJ6Vnv2qFTyoaBgiN","market":"us","size":200390},{"description":"","seq":9,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221024369/fwp_008.jpg","primary":false,"translateUrl":"","linkName":"fwp_008.jpg","type":"GRAPHIC","id":"NTFILE47J4hhchuFEZegJA","market":"us","size":283336},{"description":"","seq":10,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221024369/fwp_009.jpg","primary":false,"translateUrl":"","linkName":"fwp_009.jpg","type":"GRAPHIC","id":"NTFILECdfv949sQXdTjNAq","market":"us","size":197600},{"description":"","seq":11,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221024369/fwp_010.jpg","primary":false,"translateUrl":"","linkName":"fwp_010.jpg","type":"GRAPHIC","id":"NTFILEGqHsxqxqvWppa19i","market":"us","size":168118},{"description":"","seq":12,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221024369/fwp_011.jpg","primary":false,"translateUrl":"","linkName":"fwp_011.jpg","type":"GRAPHIC","id":"NTFILECK4cC2FmNBQuYghB","market":"us","size":270728},{"description":"","seq":13,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221024369/fwp_012.jpg","primary":false,"translateUrl":"","linkName":"fwp_012.jpg","type":"GRAPHIC","id":"NTFILEG8g3LKrFfEof3qrh","market":"us","size":217756},{"description":"","seq":14,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221024369/fwp_013.jpg","primary":false,"translateUrl":"","linkName":"fwp_013.jpg","type":"GRAPHIC","id":"NTFILE65RejnLeLtNHMPJx","market":"us","size":251469},{"description":"","seq":15,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221024369/fwp_014.jpg","primary":false,"translateUrl":"","linkName":"fwp_014.jpg","type":"GRAPHIC","id":"NTFILEE6dqop8CxegpYpw6","market":"us","size":263491},{"description":"","seq":16,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221024369/fwp_015.jpg","primary":false,"translateUrl":"","linkName":"fwp_015.jpg","type":"GRAPHIC","id":"NTFILECRWpfbejAkGq4bKu","market":"us","size":184319},{"description":"","seq":17,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221024369/fwp_016.jpg","primary":false,"translateUrl":"","linkName":"fwp_016.jpg","type":"GRAPHIC","id":"NTFILE5th9xYxUQUQPsMnX","market":"us","size":287431},{"description":"","seq":18,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221024369/fwp_017.jpg","primary":false,"translateUrl":"","linkName":"fwp_017.jpg","type":"GRAPHIC","id":"NTFILEFajDwqtji2p8LE2L","market":"us","size":213376},{"description":"","seq":19,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221024369/fwp_018.jpg","primary":false,"translateUrl":"","linkName":"fwp_018.jpg","type":"GRAPHIC","id":"NTFILE5ANXA3AdBs7N27QZ","market":"us","size":276144},{"description":"","seq":20,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221024369/fwp_019.jpg","primary":false,"translateUrl":"","linkName":"fwp_019.jpg","type":"GRAPHIC","id":"NTFILEEtgHQaaY4fGs86Yq","market":"us","size":224730},{"description":"","seq":21,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221024369/fwp_020.jpg","primary":false,"translateUrl":"","linkName":"fwp_020.jpg","type":"GRAPHIC","id":"NTFILEFD2ndcmEsRhCBtj7","market":"us","size":185330},{"description":"","seq":22,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221024369/fwp_021.jpg","primary":false,"translateUrl":"","linkName":"fwp_021.jpg","type":"GRAPHIC","id":"NTFILE8Bf8rVaooonczc6r","market":"us","size":218433}],"type_name":"招股註冊","type_name_en":"Recruitment Registration","titleTypeEn":"[Supp]Public Prospectus","us_type":"usProspectusesRegistrations","us_type_zh":"招股註冊","earn_infos":[],"event_type":"important_notice","event_name":"[補充]招股説明書","pubTime":"2021-10-01 00:00","pubTimestamp":1633017600,"title_zh":"FWP  - Filing under Securities Act Rules 163/433 of free writing prospectuses","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"13975589","market":"us","labels":[],"media":"sec.gov","original_id":"AN149315221022855-BFRI","pdf_url":"","pub_time":1631721600000,"showTitleType":true,"size":0,"source":"sec_us","summary":"S-1/A [Amend]  - General form for registration of securities under the Securities Act of 1933","symbol":"BFRI","title":"S-1/A [Amend]  - General form for registration of securities under the Securities Act of 1933","titleType":"[修訂]招股説明書","type":"usProspectusesRegistrations","url":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221022855/0001493152-21-022855-index.htm","us_notice_code":"Form S-1/A","us_title_en":"S-1/A [Amend]  - General form for registration of securities under the Securities Act of 1933","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221022855/forms-1a.htm","primary":true,"translateUrl":"","linkName":"forms-1a.htm","type":"S-1/A","id":"NTFILE7s83odRWVPH2wi8c","market":"us","size":2233136},{"description":"","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221022855/ex10-8.htm","primary":false,"translateUrl":"","linkName":"ex10-8.htm","type":"EX-10.8","id":"NTFILEC2M1JRCeVFdyoz5f","market":"us","size":153999},{"description":"","seq":3,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221022855/ex10-10.htm","primary":false,"translateUrl":"","linkName":"ex10-10.htm","type":"EX-10.10","id":"NTFILEGbT2TAQ6zWsQ47Mh","market":"us","size":69555},{"description":"","seq":4,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221022855/ex10-11.htm","primary":false,"translateUrl":"","linkName":"ex10-11.htm","type":"EX-10.11","id":"NTFILE5UufzNYgDjVF4bis","market":"us","size":87920},{"description":"","seq":5,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221022855/ex10-11_001.jpg","primary":false,"translateUrl":"","linkName":"ex10-11_001.jpg","type":"GRAPHIC","id":"NTFILE7BQCKQsrqSZtMGr9","market":"us","size":3015},{"description":"","seq":6,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221022855/ex23-1.htm","primary":false,"translateUrl":"","linkName":"ex23-1.htm","type":"EX-23.1","id":"NTFILEGsdLRn9eiXTxSC1a","market":"us","size":3744},{"description":"","seq":7,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221022855/forms-1_001.jpg","primary":false,"translateUrl":"","linkName":"forms-1_001.jpg","type":"GRAPHIC","id":"NTFILE9W993YE1EkJMFY4S","market":"us","size":83719},{"description":"","seq":8,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221022855/f_001.jpg","primary":false,"translateUrl":"","linkName":"f_001.jpg","type":"GRAPHIC","id":"NTFILEA8DCaZk5UFFvx5Ni","market":"us","size":13530},{"description":"","seq":9,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221022855/forms-1_002.jpg","primary":false,"translateUrl":"","linkName":"forms-1_002.jpg","type":"GRAPHIC","id":"NTFILEGBoEwRtBkTeiK1df","market":"us","size":9770},{"description":"","seq":10,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221022855/forms-1_003.jpg","primary":false,"translateUrl":"","linkName":"forms-1_003.jpg","type":"GRAPHIC","id":"NTFILEEKuQBVdHGBugyxPt","market":"us","size":12163},{"description":"","seq":11,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221022855/forms-1_004.jpg","primary":false,"translateUrl":"","linkName":"forms-1_004.jpg","type":"GRAPHIC","id":"NTFILE62iF2u6Yb6TaJuvL","market":"us","size":52065},{"description":"","seq":12,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221022855/forms-1_005.jpg","primary":false,"translateUrl":"","linkName":"forms-1_005.jpg","type":"GRAPHIC","id":"NTFILE4EPbyWrcMtPv2rRh","market":"us","size":83719}],"type_name":"招股註冊","type_name_en":"Recruitment Registration","titleTypeEn":"[Amend]Public Prospectus","us_type":"usProspectusesRegistrations","us_type_zh":"招股註冊","earn_infos":[],"event_type":"important_notice","event_name":"[修訂]招股説明書","pubTime":"2021-09-16 00:00","pubTimestamp":1631721600,"title_zh":"S-1/A [Amend]  - General form for registration of securities under the Securities Act of 1933","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"13975590","market":"us","labels":[],"media":"sec.gov","original_id":"AN149315221022857-BFRI","pdf_url":"","pub_time":1631635200000,"showTitleType":true,"size":0,"source":"sec_us","summary":"CORRESP [Cover] - Correspondence","symbol":"BFRI","title":"CORRESP [Cover] - Correspondence","titleType":"SEC問詢函","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221022857/0001493152-21-022857-index.htm","us_notice_code":"Form CORRESP","us_title_en":"CORRESP [Cover] - Correspondence","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221022857/filename1.htm","primary":true,"translateUrl":"","linkName":"filename1.htm","type":"CORRESP","id":"NTFILE4BUEK5mU5znYJefe","market":"us","size":43842},{"description":"","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221022857/corresp_001.jpg","primary":false,"translateUrl":"","linkName":"corresp_001.jpg","type":"GRAPHIC","id":"NTFILEGKpX5ywbX4zr7N6E","market":"us","size":6110}],"type_name":"交易披露","type_name_en":"Transaction Related","titleTypeEn":"Correspondence","us_type":"usAnnouncement","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"SEC問詢函","pubTime":"2021-09-15 00:00","pubTimestamp":1631635200,"title_zh":"CORRESP [Cover] - Correspondence","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"13975592","market":"us","labels":[],"media":"sec.gov","original_id":"AN149315221021596-BFRI","pdf_url":"","pub_time":1630339200000,"showTitleType":true,"size":0,"source":"sec_us","summary":"S-1/A [Amend]  - General form for registration of securities under the Securities Act of 1933","symbol":"BFRI","title":"S-1/A [Amend]  - General form for registration of securities under the Securities Act of 1933","titleType":"[修訂]招股説明書","type":"usProspectusesRegistrations","url":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221021596/0001493152-21-021596-index.htm","us_notice_code":"Form S-1/A","us_title_en":"S-1/A [Amend]  - General form for registration of securities under the Securities Act of 1933","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221021596/forms-1a.htm","primary":true,"translateUrl":"","linkName":"forms-1a.htm","type":"S-1/A","id":"NTFILEJCWoP2XW6iMMg66X","market":"us","size":2209131},{"description":"","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221021596/ex23-1.htm","primary":false,"translateUrl":"","linkName":"ex23-1.htm","type":"EX-23.1","id":"NTFILEEvC8diTgRfcWkh1p","market":"us","size":3741},{"description":"","seq":3,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221021596/forms-1_001.jpg","primary":false,"translateUrl":"","linkName":"forms-1_001.jpg","type":"GRAPHIC","id":"NTFILE9cTEqvzbhuMXVe2a","market":"us","size":83719},{"description":"","seq":4,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221021596/f_001.jpg","primary":false,"translateUrl":"","linkName":"f_001.jpg","type":"GRAPHIC","id":"NTFILE2jCHzEy3LXtw5gjY","market":"us","size":13530},{"description":"","seq":5,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221021596/forms-1_002.jpg","primary":false,"translateUrl":"","linkName":"forms-1_002.jpg","type":"GRAPHIC","id":"NTFILEFfwNKms5WNphnNoS","market":"us","size":9770},{"description":"","seq":6,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221021596/forms-1_003.jpg","primary":false,"translateUrl":"","linkName":"forms-1_003.jpg","type":"GRAPHIC","id":"NTFILE9p33m1Y82TuHGSJP","market":"us","size":12163},{"description":"","seq":7,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221021596/forms-1_004.jpg","primary":false,"translateUrl":"","linkName":"forms-1_004.jpg","type":"GRAPHIC","id":"NTFILE2ji3r9md3D5QyQsa","market":"us","size":52065},{"description":"","seq":8,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221021596/forms-1_005.jpg","primary":false,"translateUrl":"","linkName":"forms-1_005.jpg","type":"GRAPHIC","id":"NTFILE9UbZj1uj9Aip4RHU","market":"us","size":83719}],"type_name":"招股註冊","type_name_en":"Recruitment Registration","titleTypeEn":"[Amend]Public Prospectus","us_type":"usProspectusesRegistrations","us_type_zh":"招股註冊","earn_infos":[],"event_type":"important_notice","event_name":"[修訂]招股説明書","pubTime":"2021-08-31 00:00","pubTimestamp":1630339200,"title_zh":"S-1/A [Amend]  - General form for registration of securities under the Securities Act of 1933","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"13975593","market":"us","labels":[],"media":"sec.gov","original_id":"AN149315221021598-BFRI","pdf_url":"","pub_time":1630252800000,"showTitleType":true,"size":0,"source":"sec_us","summary":"CORRESP [Cover] - Correspondence","symbol":"BFRI","title":"CORRESP [Cover] - Correspondence","titleType":"SEC問詢函","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221021598/0001493152-21-021598-index.htm","us_notice_code":"Form CORRESP","us_title_en":"CORRESP [Cover] - Correspondence","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221021598/filename1.htm","primary":true,"translateUrl":"","linkName":"filename1.htm","type":"CORRESP","id":"NTFILEGxhzpsXX5UL17nww","market":"us","size":25987},{"description":"","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221021598/image_001.jpg","primary":false,"translateUrl":"","linkName":"image_001.jpg","type":"GRAPHIC","id":"NTFILE8xgxJWiToM9foSQr","market":"us","size":6110}],"type_name":"交易披露","type_name_en":"Transaction Related","titleTypeEn":"Correspondence","us_type":"usAnnouncement","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"SEC問詢函","pubTime":"2021-08-30 00:00","pubTimestamp":1630252800,"title_zh":"CORRESP [Cover] - Correspondence","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"13975595","market":"us","labels":[],"media":"sec.gov","original_id":"AN149315221019428-BFRI","pdf_url":"","pub_time":1628697600000,"showTitleType":true,"size":0,"source":"sec_us","summary":"S-1/A [Amend]  - General form for registration of securities under the Securities Act of 1933","symbol":"BFRI","title":"S-1/A [Amend]  - General form for registration of securities under the Securities Act of 1933","titleType":"[修訂]招股説明書","type":"usProspectusesRegistrations","url":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221019428/0001493152-21-019428-index.htm","us_notice_code":"Form S-1/A","us_title_en":"S-1/A [Amend]  - General form for registration of securities under the Securities Act of 1933","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221019428/forms-1a.htm","primary":true,"translateUrl":"","linkName":"forms-1a.htm","type":"S-1/A","id":"NTFILE2wxPBph3Q7UEJ5sD","market":"us","size":2617703},{"description":"","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221019428/ex10-6.htm","primary":false,"translateUrl":"","linkName":"ex10-6.htm","type":"EX-10.6","id":"NTFILEEJ1Gr6tQuN4RLTWc","market":"us","size":79558},{"description":"","seq":3,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221019428/ex10-11.htm","primary":false,"translateUrl":"","linkName":"ex10-11.htm","type":"EX-10.11","id":"NTFILEFBQbZSzimXhLnWVK","market":"us","size":84611},{"description":"","seq":4,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221019428/ex23-1.htm","primary":false,"translateUrl":"","linkName":"ex23-1.htm","type":"EX-23.1","id":"NTFILE4FiyH726VxzrRLV9","market":"us","size":3741},{"description":"","seq":5,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221019428/ex99-1.htm","primary":false,"translateUrl":"","linkName":"ex99-1.htm","type":"EX-99.1","id":"NTFILE3fFZKkU7dxR8mdp1","market":"us","size":4479},{"description":"","seq":6,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221019428/ex99-2.htm","primary":false,"translateUrl":"","linkName":"ex99-2.htm","type":"EX-99.2","id":"NTFILE5fFCjM5VPBMKEtxD","market":"us","size":4609},{"description":"","seq":7,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221019428/ex99-3.htm","primary":false,"translateUrl":"","linkName":"ex99-3.htm","type":"EX-99.3","id":"NTFILEFJJHsa5xihmmMiTo","market":"us","size":3227},{"description":"","seq":8,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221019428/forms-1_001.jpg","primary":false,"translateUrl":"","linkName":"forms-1_001.jpg","type":"GRAPHIC","id":"NTFILE6JBgYphXnqy4nTrD","market":"us","size":83719},{"description":"","seq":9,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221019428/f_001.jpg","primary":false,"translateUrl":"","linkName":"f_001.jpg","type":"GRAPHIC","id":"NTFILE2jssYkk6mnkAMbA1","market":"us","size":13530},{"description":"","seq":10,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221019428/forms-1_002.jpg","primary":false,"translateUrl":"","linkName":"forms-1_002.jpg","type":"GRAPHIC","id":"NTFILE9NF7mccUx4Uh3GzH","market":"us","size":9770},{"description":"","seq":11,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221019428/forms-1_003.jpg","primary":false,"translateUrl":"","linkName":"forms-1_003.jpg","type":"GRAPHIC","id":"NTFILEGJvhG61hciqJBqRv","market":"us","size":12163},{"description":"","seq":12,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221019428/forms-1_004.jpg","primary":false,"translateUrl":"","linkName":"forms-1_004.jpg","type":"GRAPHIC","id":"NTFILE6iJ9FrMLjxrksTDx","market":"us","size":52065},{"description":"","seq":13,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221019428/forms-1_005.jpg","primary":false,"translateUrl":"","linkName":"forms-1_005.jpg","type":"GRAPHIC","id":"NTFILEe3Qko6hBV57cYGHW","market":"us","size":83719},{"description":"","seq":14,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221019428/ex10-6_001.jpg","primary":false,"translateUrl":"","linkName":"ex10-6_001.jpg","type":"GRAPHIC","id":"NTFILECBshp2z4L521pSpN","market":"us","size":3015},{"description":"","seq":15,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221019428/ex10-11_001.jpg","primary":false,"translateUrl":"","linkName":"ex10-11_001.jpg","type":"GRAPHIC","id":"NTFILE9Yr3Q8JNCJXDP3H3","market":"us","size":2618}],"type_name":"招股註冊","type_name_en":"Recruitment Registration","titleTypeEn":"[Amend]Public Prospectus","us_type":"usProspectusesRegistrations","us_type_zh":"招股註冊","earn_infos":[],"event_type":"important_notice","event_name":"[修訂]招股説明書","pubTime":"2021-08-12 00:00","pubTimestamp":1628697600,"title_zh":"S-1/A [Amend]  - General form for registration of securities under the Securities Act of 1933","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"13975596","market":"us","labels":[],"media":"sec.gov","original_id":"AN149315221019429-BFRI","pdf_url":"","pub_time":1628611200000,"showTitleType":true,"size":0,"source":"sec_us","summary":"CORRESP [Cover] - Correspondence","symbol":"BFRI","title":"CORRESP [Cover] - Correspondence","titleType":"SEC問詢函","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221019429/0001493152-21-019429-index.htm","us_notice_code":"Form CORRESP","us_title_en":"CORRESP [Cover] - Correspondence","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221019429/filename1.htm","primary":true,"translateUrl":"","linkName":"filename1.htm","type":"CORRESP","id":"NTFILE9JrCJvcbifrvdN3c","market":"us","size":42731},{"description":"","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1858685/000149315221019429/corresp_001.jpg","primary":false,"translateUrl":"","linkName":"corresp_001.jpg","type":"GRAPHIC","id":"NTFILE4LeyqJJRT2g7THJg","market":"us","size":7150}],"type_name":"交易披露","type_name_en":"Transaction Related","titleTypeEn":"Correspondence","us_type":"usAnnouncement","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"SEC問詢函","pubTime":"2021-08-11 00:00","pubTimestamp":1628611200,"title_zh":"CORRESP [Cover] - Correspondence","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0}],"pageSize":20,"totalPage":11,"pageCount":10,"totalSize":204,"code":"91000000","status":"200"}]}}