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Ionis Pharmaceuticals, Inc

42.56

-1.1100-2.54%

成交量：127.23万

成交额：5,445.18万

市值：70.73亿

市盈率：-12.23

高：43.58

开：43.55

低：42.38

收：43.67

52周最高：86.74

52周最低：42.38

股本：1.66亿

流通股本：1.62亿

量比：0.46

换手率：0.79%

股息：- -

股息率：- -

每股收益(TTM):-3.4800

每股收益(LYR):-2.3812

净资产收益率：-105.50%

总资产收益率：-12.42%

市净率：16.08

市盈率(LYR):-17.87

数据加载中...

总览公司新闻资讯公告

异动解读｜Ionis Pharmaceuticals盘中上涨5.31%，sefaxersen三期试验达成主要终点

异动解读｜Ionis Pharmaceuticals夜盘上涨5.89%，sefaxersen三期试验达到主要终点

异动解读｜Ionis Pharmaceuticals盘中上涨5.15%，连续两项三期试验取得积极结果提振市场信心

异动解读｜Ionis Pharmaceuticals盘中下跌5.05%，多项管线利好未能扭转心血管管线失利后持续抛压

Ionis Pharmaceuticals（IONS）涨超2% 三期试验取得积极结果

异动解读｜Ionis Pharmaceuticals盘前上涨5.9%，多款在研药物三期试验接连达主要终点

异动解读｜Ionis Pharmaceuticals夜盘上涨5.9%，Ulefnersen三期Fusion研究达主要终点

Ionis制药Sefaxersen在37周时显著降低蛋白尿，与安慰剂相比达到统计学意义

Ionis制药公司：Imagination研究将继续以盲性试验形式评估肾功能两年期变化

Ionis公布合作方罗氏在IgA肾病领域Phase 3研究——Imagination试验的中期数据喜人

Ionis制药：Sefaxersen安全性数据与此前一致，未发现新的安全信号

大冢制药与Ionis合作开发的ALS试验性药物在晚期临床试验中达到主要研究目标

异动解读｜Ionis Pharmaceuticals盘前上涨7.15%，Ulefnersen三期Fusion研究达主要终点

Ionis Pharmaceuticals：Ulefnersen在Fus-ALS关键终点上取得统计学显著改善

Ionis公布Ulefnersen三期Fusion研究积极顶线结果，推进FUS-ALS首个潜在疾病修饰疗法迈出关键一步

异动解读｜Ionis Pharmaceuticals盘中下跌5.01%，心血管管线接连失利叠加机构下调目标价持续承压

异动解读｜Ionis Pharmaceuticals盘中上涨5.03%，报45.78美元

异动解读｜Ionis Pharmaceuticals盘中下跌5.25%，心血管管线接连失利持续承压

异动解读｜Ionis Pharmaceuticals盘中下跌6.29%，心脏病药物试验接连失败持续承压

美国研究综述-阿甘、马斯特克、甲骨文

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Pharmaceuticals盘中上涨5.15%，连续两项三期试验取得积极结果提振市场信心","url":"https://stock-news.laohu8.com/highlight/detail?id=1161973403","media":"行情直击","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1161973403?lang=zh_cn&edition=fundamental","pubTime":"2026-09-29 02:37","pubTimestamp":1790620649,"startTime":"0","endTime":"0","summary":"9月29日，Ionis Pharmaceuticals盘中上涨5.15%，报46.79美元/股，成交额8349.88万美元。两项试验连续成功，叠加此前zilganersen获FDA批准治疗亚历山大病，有效修复了7月心脏病药物eplontersen三期试验失败以来的市场信心。（以上内容均基于市场公开消息，由程序或算法智能生成，仅作为股价异动提醒，不作为投资建议或交易依据。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":"Ionis连获两项三期成功，股价上涨提振信心","news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1110509386","title":"异动解读｜Ionis Pharmaceuticals盘中下跌5.05%，多项管线利好未能扭转心血管管线失利后持续抛压","url":"https://stock-news.laohu8.com/highlight/detail?id=1110509386","media":"行情直击","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1110509386?lang=zh_cn&edition=fundamental","pubTime":"2026-09-23 22:57","pubTimestamp":1790175464,"startTime":"0","endTime":"0","summary":"9月23日，Ionis Pharmaceuticals盘中下跌5.05%，报43.44美元/股，成交额3311.68万美元。尽管当日公司迎来密集管线利好，股价仍大幅回落。然而，市场对此反应冷淡，盘前涨幅迅速回吐并转为下跌。背景上，公司此前与阿斯利康合作的eplontersen在ATTR心肌病三期试验中未达主要终点，叠加美国银行、TD Cowen等机构接连下调目标价，心血管核心管线的接连失利已严重削弱市场信心，股价自52周高点86.74美元已累计腰斩过半，利好消息短期内难以扭转悲观预期。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":"Ionis盘中下跌，多项利好难挽抛压","news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2669488169","title":"Ionis Pharmaceuticals（IONS）涨超2% 三期试验取得积极结果","url":"https://stock-news.laohu8.com/highlight/detail?id=2669488169","media":"金吾财讯","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2669488169?lang=zh_cn&edition=fundamental","pubTime":"2026-09-23 19:15","pubTimestamp":1790162157,"startTime":"0","endTime":"0","summary":"金吾财讯 | Ionis Pharmaceuticals（IONS）美股盘前股价上扬，最新涨2.25%，报46.78美元。消息面上，Ionis Pharmaceuticals的sefaxersen在三期IMAgINATION临床试验达到原发性IgA肾病（IgAN）成人患者主要终点。试验第37周数据显示，sefaxersen可显著降低患者24小时尿蛋白肌酐比值（UPCR），蛋白尿降幅具备统计学与临床意义，该指标是肾损伤核心标志物。这款皮下注射药物的安全性、耐受性与此前研究数据保持一致，未出现新增安全风险。","market":"nz","thumbnail":"https://static.szfiu.com/news/20250107/MDYxNTA2ZjhkOWVmNGY4NWFiMzk3MGE5NjBhODhjODE3MzYyMzc3Njg0MzY=.png","type":0,"news_type":0,"thumbnails":["https://static.szfiu.com/news/20250107/MDYxNTA2ZjhkOWVmNGY4NWFiMzk3MGE5NjBhODhjODE3MzYyMzc3Njg0MzY=.png"],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"306389","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1184074764","title":"异动解读｜Ionis Pharmaceuticals盘前上涨5.9%，多款在研药物三期试验接连达主要终点","url":"https://stock-news.laohu8.com/highlight/detail?id=1184074764","media":"行情直击","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1184074764?lang=zh_cn&edition=fundamental","pubTime":"2026-09-23 16:01","pubTimestamp":1790150471,"startTime":"0","endTime":"0","summary":"9月23日，Ionis Pharmaceuticals盘前上涨5.9%，报47.6美元/股，成交额7.51万美元。消息面上，公司近日迎来多重管线利好共振。其与大冢制药合作的Ulefnersen在治疗FUS基因突变型肌萎缩侧索硬化症的三期Fusion研究中达到主要终点，显著改善患者生存与功能，关键次要终点亦获达成，双方计划与FDA讨论加速审批路径。此外，公司此前已获FDA批准Zilganersen用于治疗亚历山大病，商业化进程持续推进。","market":"hk","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":"Ionis多管线告捷，盘前迎来上涨","news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1116292294","title":"异动解读｜Ionis Pharmaceuticals夜盘上涨5.9%，Ulefnersen三期Fusion研究达主要终点","url":"https://stock-news.laohu8.com/highlight/detail?id=1116292294","media":"行情直击","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1116292294?lang=zh_cn&edition=fundamental","pubTime":"2026-09-23 14:33","pubTimestamp":1790145188,"startTime":"0","endTime":"0","summary":"9月22日，Ionis Pharmaceuticals夜盘上涨5.9%，报48.45美元/股，成交额25.97万美元。消息面上，公司宣布其试验性药物Ulefnersen在治疗FUS基因突变型肌萎缩侧索硬化症的三期Fusion研究中取得积极顶线结果，主要终点实现具有统计学意义的显著改善。Ulefnersen是一种反义寡核苷酸药物，旨在从根源干预疾病进程，若最终获批将成为FUS-ALS领域首个潜在的疾病修饰疗法，填补该适应症治疗空白。此外，公司另一在研药物Zilganersen的FDA目标审评日期亦定于9月22日，多重催化剂共振推动股价走强。","market":"hk","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":"Ionis夜盘大涨，ALS新药三期达主要终点","news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1174768916","title":"Ionis制药Sefaxersen在37周时显著降低蛋白尿，与安慰剂相比达到统计学意义","url":"https://stock-news.laohu8.com/highlight/detail?id=1174768916","media":"美股速递","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1174768916?lang=zh_cn&edition=fundamental","pubTime":"2026-09-23 13:05","pubTimestamp":1790139946,"startTime":"0","endTime":"0","summary":"Ionis制药宣布，其候选药物Sefaxersen在37周的治疗周期中展现出令人瞩目的疗效——与安慰剂相比，该药物成功实现了蛋白尿水平的统计学显著下降。Sefaxersen交出的这份答卷，不仅凸显了其潜在的治疗价值，更可能为无数深受肾病困扰的患者打开一扇新的大门。Ionis制药此番披露的结果，源自一项严谨的临床试验评估。数据表明，在预设的时间节点上，接受Sefaxersen治疗的患者组，其蛋白尿指标改善幅度明显优于对照组，差异具备统计学意义。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1191744078","title":"Ionis制药公司：Imagination研究将继续以盲性试验形式评估肾功能两年期变化","url":"https://stock-news.laohu8.com/highlight/detail?id=1191744078","media":"美股速递","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1191744078?lang=zh_cn&edition=fundamental","pubTime":"2026-09-23 13:05","pubTimestamp":1790139942,"startTime":"0","endTime":"0","summary":"Ionis制药公司宣布，其Imagination研究将维持盲性试验设计，持续追踪并评估受试者肾功能在两年时间跨度内的演变趋势。这一决策意味着该研究将继续在双盲条件下推进，以确保数据采集的客观性与严谨性。研究者将密切监测肾功能的各项关键指标，力求揭示药物干预对肾脏健康的长期影响。此举也反映了公司对临床证据质量的高度重视，为后续潜在疗法验证奠定坚实基础。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1143010400","title":"Ionis公布合作方罗氏在IgA肾病领域Phase 3研究——Imagination试验的中期数据喜人","url":"https://stock-news.laohu8.com/highlight/detail?id=1143010400","media":"美股速递","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1143010400?lang=zh_cn&edition=fundamental","pubTime":"2026-09-23 13:01","pubTimestamp":1790139668,"startTime":"0","endTime":"0","summary":"Ionis Pharmaceuticals今日宣布，其合作伙伴罗氏（Roche）在IgA肾病（IgAN）治疗领域所开展的Phase 3临床试验——Imagination研究，中期数据表现积极。这一消息，为众多受IgA肾病困扰的患者群体带来了新的希望曙光。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1151045889","title":"Ionis制药：Sefaxersen安全性数据与此前一致，未发现新的安全信号","url":"https://stock-news.laohu8.com/highlight/detail?id=1151045889","media":"美股速递","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1151045889?lang=zh_cn&edition=fundamental","pubTime":"2026-09-23 13:01","pubTimestamp":1790139668,"startTime":"0","endTime":"0","summary":"Ionis制药公司表示，其候选药物Sefaxersen的安全性与既往数据保持一致——未识别出任何新的安全警示信号。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2669422144","title":"大冢制药与Ionis合作开发的ALS试验性药物在晚期临床试验中达到主要研究目标","url":"https://stock-news.laohu8.com/highlight/detail?id=2669422144","media":"路透中文","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2669422144?lang=zh_cn&edition=fundamental","pubTime":"2026-09-22 20:36","pubTimestamp":1790080585,"startTime":"0","endTime":"0","summary":"大冢制药与Ionis合作开发的ALS试验性药物在晚期临床试验中达到主要研究目标路透9月22日-大冢制药和Ionis制药公司周二表示，其试验性药物在针对罕见遗传性肌萎缩侧索硬化症患者的晚期临床试验中达到了主要研究目标。目前尚无针对FUS-ALS遗传病因的获批疗法。此外，大冢制药还为无法参与临床试验的符合条件的FUS-ALS患者启动了一项全球早期使用计划，允许医生在该药物获得任何潜在批准之前申请使用ulefnersen。","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260922:nL4S45E0TG:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1172335676","title":"异动解读｜Ionis Pharmaceuticals盘前上涨7.15%，Ulefnersen三期Fusion研究达主要终点","url":"https://stock-news.laohu8.com/highlight/detail?id=1172335676","media":"行情直击","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1172335676?lang=zh_cn&edition=fundamental","pubTime":"2026-09-22 20:05","pubTimestamp":1790078701,"startTime":"0","endTime":"0","summary":"9月22日，Ionis Pharmaceuticals盘前上涨7.15%，报46.95美元/股，成交额44.1万美元。消息面上，公司宣布其试验性药物Ulefnersen在治疗FUS基因突变型肌萎缩侧索硬化症的三期Fusion研究中取得积极顶线结果，主要终点实现具有统计学意义的显著改善。Ulefnersen是一种反义寡核苷酸药物，旨在从根源干预疾病进程，若最终获批将成为FUS-ALS领域首个潜在的疾病修饰疗法，填补该适应症治疗空白。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":"Ionis盘前上涨，FUS-ALS新药三期达主要终点","news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1191604640","title":"Ionis Pharmaceuticals：Ulefnersen在Fus-ALS关键终点上取得统计学显著改善","url":"https://stock-news.laohu8.com/highlight/detail?id=1191604640","media":"美股速递","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1191604640?lang=zh_cn&edition=fundamental","pubTime":"2026-09-22 20:01","pubTimestamp":1790078499,"startTime":"0","endTime":"0","summary":"Ionis Pharmaceuticals公司近日宣布，其试验性药物Ulefnersen在治疗FUS基因突变型肌萎缩侧索硬化症的临床研究中，于主要终点上实现了具有统计学意义的显著改善。Ionis Pharmaceuticals凭借其反义寡核苷酸技术平台，致力于开发能够精准靶向疾病根源的创新疗法，Ulefnersen正是这一战略布局下的重要候选药物。公司方面表示，这些令人鼓舞的临床数据将进一步支持Ulefnersen的持续推进，并计划在未来的医学会议上公布详细研究结果，同时与监管机构沟通后续开发路径。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1115354806","title":"Ionis公布Ulefnersen三期Fusion研究积极顶线结果，推进FUS-ALS首个潜在疾病修饰疗法迈出关键一步","url":"https://stock-news.laohu8.com/highlight/detail?id=1115354806","media":"美股速递","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1115354806?lang=zh_cn&edition=fundamental","pubTime":"2026-09-22 20:01","pubTimestamp":1790078494,"startTime":"0","endTime":"0","summary":"Ionis制药公司今日宣布，其针对Ulefnersen的三期Fusion研究取得了积极的顶线结果。这一里程碑式的进展，标志着该公司在推动FUS-ALS首个潜在疾病修饰疗法方面，踏出了至关重要的一步。该研究旨在评估Ulefnersen在治疗特定基因突变型ALS患者中的疗效与安全性。Ulefnersen作为一种反义寡核苷酸药物，其设计初衷是从根源上干预疾病进程。业内观察人士指出，这项突破若最终获得批准，不仅将填补FUS-ALS领域的治疗空白，更可能重塑整个ALS治疗格局。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1124966303","title":"异动解读｜Ionis Pharmaceuticals盘中下跌5.01%，心血管管线接连失利叠加机构下调目标价持续承压","url":"https://stock-news.laohu8.com/highlight/detail?id=1124966303","media":"行情直击","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1124966303?lang=zh_cn&edition=fundamental","pubTime":"2026-09-19 03:59","pubTimestamp":1789761565,"startTime":"0","endTime":"0","summary":"9月19日，Ionis Pharmaceuticals盘中下跌5.01%，报44.4美元/股，成交额1.46亿美元，股价延续近期跌势。消息面上，公司心血管核心管线近期接连遭遇重挫。两次关键管线的接连失利严重削弱了市场对公司核心研发实力的信心。此外，美国银行将公司目标价从93美元下调至91美元，TD Cowen亦将目标价从108美元下调至94美元，机构预期持续回落加剧了抛压。","market":"hk","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":"Ionis心血管管线接连失利，股价承压下行","news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1124058402","title":"异动解读｜Ionis Pharmaceuticals盘中上涨5.03%，报45.78美元","url":"https://stock-news.laohu8.com/highlight/detail?id=1124058402","media":"行情直击","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1124058402?lang=zh_cn&edition=fundamental","pubTime":"2026-09-17 21:43","pubTimestamp":1789652612,"startTime":"0","endTime":"0","summary":"9月17日，Ionis Pharmaceuticals盘中上涨5.03%，报45.78美元/股，成交额728.41万美元。Ionis Pharmaceuticals所在的生物科技行业中，个股中，Moderna涨5.06%，安进涨0.42%，Hyperliquid Strategies涨7.56%，bioAffinity Technologies涨24.3%，Praxis Precision Medicines涨0.36%。（以上内容均基于市场公开消息，由程序或算法智能生成，仅作为股价异动提醒，不作为投资建议或交易依据。）","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1141743387","title":"异动解读｜Ionis Pharmaceuticals盘中下跌5.25%，心血管管线接连失利持续承压","url":"https://stock-news.laohu8.com/highlight/detail?id=1141743387","media":"行情直击","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1141743387?lang=zh_cn&edition=fundamental","pubTime":"2026-09-17 03:13","pubTimestamp":1789585996,"startTime":"0","endTime":"0","summary":"9月17日，Ionis Pharmaceuticals盘中下跌5.25%，报44.77美元/股，成交额2.02亿美元，股价延续近期跌势。消息面上，公司心血管核心管线接连遭遇重挫。9月8日，公司与诺华联合开发的心脏病药物pelacarsen在晚期临床试验中未达主要终点，当日盘前即暴跌13%。两次关键心血管管线的接连失利严重削弱了市场对公司核心研发实力的信心。此外，美国银行近期将公司目标价从93美元下调至91美元，TD Cowen亦将目标价从108美元下调至94美元，机构预期持续回落加剧了抛压。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":"Ionis心血管管线接连失利，股价持续承压","news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1159701623","title":"异动解读｜Ionis Pharmaceuticals盘中下跌6.29%，心脏病药物试验接连失败持续承压","url":"https://stock-news.laohu8.com/highlight/detail?id=1159701623","media":"行情直击","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1159701623?lang=zh_cn&edition=fundamental","pubTime":"2026-09-16 00:13","pubTimestamp":1789488811,"startTime":"0","endTime":"0","summary":"9月15日，Ionis Pharmaceuticals盘中下跌6.29%，报48.2美元/股，成交额9541.81万美元，股价延续近期颓势。9月8日，公司与诺华联合开发的心脏病药物pelacarsen在晚期临床试验中未达主要终点，当日盘前即暴跌13%。此前7月，公司与阿斯利康合作的Eplontersen针对淀粉样心肌病的三期试验同样宣告失败，股价曾单日暴跌超20%。两次关键心血管管线的接连失利严重削弱了市场对公司核心研发实力的信心。","market":"hk","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":"心脏病药物试验接连失败，Ionis股价承压下跌","news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2666300103","title":"美国研究综述-阿甘、马斯特克、甲骨文","url":"https://stock-news.laohu8.com/highlight/detail?id=2666300103","media":"路透中文","labels":["shareholding"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2666300103?lang=zh_cn&edition=fundamental","pubTime":"2026-09-09 14:56","pubTimestamp":1788936998,"startTime":"0","endTime":"0","summary":"美国研究综述-阿甘、马斯特克、甲骨文路透9月9日-周三，华尔街的证券分析师们**修订了**多家在美国上市公司的评级和目标股价，其中包括**阿甘公司**、**马斯特克公司**和**甲骨文公司**。股票条目按字母顺序排列。","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260909:nL4S4510GG:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"shareholding","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LRCX","QCOM","PICK","POW","NXT","CASY","RULE","PRIM","PWR","XE","HP","FSLR","OKLS","IVZ","LIND","NLR","ORCU","MTZ","QQQG","AGX","JOUL","TTAN","QCMU","PSCI","FWONK","HWAY","AES","DYN","OKLO","CHYM","SORCLmain","EPAI","IONS","STLD","IETC","COWG","TARS","BEN","TAN","CC","POWR","QCMD","ORCL","ORA","RS","FWONA","NUE","SMOG","FLNC","BAI"],"isVideo":false,"video":null,"gpt_icon":0}],"pageSize":20,"totalPage":5,"pageCount":1,"totalSize":81,"code":"91000000","status":"200"}]}}