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SPYRE THERAPEUTICS INC

106.65

+0.16000.15%

Post-market: 106.810.1600+0.15%16:29 EDT

Volume:640.56K

Turnover:68.38M

Market Cap:9.40B

PE:-53.06

High:108.02

Open:106.49

Low:104.94

Close:106.49

52wk High:110.18

52wk Low:14.51

Shares:88.17M

Float Shares:80.98M

Volume Ratio:0.68

T/O Rate:0.79%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-2.0100

EPS(LYR):-1.9755

ROE:-22.98%

ROA:-19.81%

PB:9.85

PE(LYR):-53.99

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Overview Company News Filings

Spyre Therapeutics (SYRE) Receives a Rating Update from a Top Analyst

Spyre Therapeutics Completes First-in-Human Study of SPY001-001, De-risking Early Pipeline

Spyre Therapeutics (SYRE) Valuation After Accelerated SKYWAY Trial Timeline And Rising Investor Interest

Simply Wall St.

Spyre Therapeutics (SYRE) Is Up 7.3% After Accelerating SPY072 Phase 2 POC Timeline - Has The Bull Case Changed?

Simply Wall St.

Analysts’ Top Healthcare Picks: Oneview Healthcare Chess Depository Interests repr 1 (ONVVF), Spyre Therapeutics (SYRE)

Spyre Therapeutics completes recruitment for SKYWAY basket trial sub-study

BRIEF-Spyre Announces Acceleration Of Expected Topline Readout Of Skyway Rheumatoid Arthritis Sub-Study To Q3 2026

Spyre Therapeutics Inc - Skyline Uc Trial Enrolling Ahead of Schedule; Part a Readouts Begin Q2 2026

THOMSON REUTERS

Spyre Therapeutics Inc - Psa and Axspa Sub-Study Recruitment on Track; Topline Data Expected Q4 2026

THOMSON REUTERS

Spyre Therapeutics Grants Inducement Stock Options for 46,600 Shares

Spyre Therapeutics Announces Grants of Inducement Awards

Spyre Therapeutics CFO Scott L Burrows Disposes of Common Shares

Spyre Therapeutics CEO Cameron Turtle Disposes of Common Shares

Spyre Therapeutics to Participate in Upcoming March Investor Conferences

Stock Track | Spyre Therapeutics Soars 5.51% Intraday After Deutsche Bank Raises Target Price

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The options have a 10-year term with an exercise price of $42.49 per share and vest 25% after one year, with the remainder vesting monthly in equal installments over the following three years, subject to continued service.","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260306:nNDL3xQp4j:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SG9999014021.USD","IE00BGHQF748.EUR","BK4112","NDAQ","SYRE","BK4585","BK4139","BK4588","LU2210149790.SGD","LU0314104364.USD","IE00B64PRP62.GBP","IE00B3QW5Z07.USD","LU2210150020.SGD","SG9999014039.USD","IE00BKPKM429.USD","SG9999014005.SGD","LU2095319765.USD","SG9999014013.SGD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2617595658","title":"Spyre Therapeutics Announces Grants of Inducement Awards","url":"https://stock-news.laohu8.com/highlight/detail?id=2617595658","media":"GlobeNewswire","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2617595658?lang=en_us&edition=fundamental","pubTime":"2026-03-07 05:05","pubTimestamp":1772831100,"startTime":"0","endTime":"0","summary":"WALTHAM, Mass., March  06, 2026  (GLOBE NEWSWIRE) -- Spyre Therapeutics, Inc. 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Chief Financial Officer Scott L. Burrows reported a disposal of common shares of the company. The full filing can be accessed through the link below.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Spyre Therapeutics Inc. published the original content used to generate this news brief via EDGAR, the Electronic Data Gathering, Analysis, and Retrieval system operated by the U.S. Securities and Exchange Commission , on March 03, 2026, and is solely responsible for the information contained therein.","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260304:nNDL4fqDhC:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"shareholding,insiderTrades","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SYRE","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2616012304","title":"Spyre Therapeutics CEO Cameron Turtle Disposes of Common Shares","url":"https://stock-news.laohu8.com/highlight/detail?id=2616012304","media":"Reuters","labels":["shareholding","insiderTrades"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2616012304?lang=en_us&edition=fundamental","pubTime":"2026-03-04 10:32","pubTimestamp":1772591530,"startTime":"0","endTime":"0","summary":"Spyre Therapeutics, Inc. beneficial owner Cameron Turtle, Chief Executive Officer and Director, reported a disposal of common shares. 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