US StockDetailed Quotes

Provided by Tiger Trade Technology Pte. Ltd.

Krystal Biotech Inc.

340.77

-5.8100-1.68%

Volume:102.02K

Turnover:34.85M

Market Cap:10.09B

PE:42.78

High:346.55

Open:343.51

Low:337.09

Close:346.58

52wk High:382.54

52wk Low:136.73

Shares:29.60M

Float Shares:23.54M

Volume Ratio:0.67

T/O Rate:0.43%

Dividend:- -

Dividend Rate:- -

EPS(TTM):7.97

EPS(LYR):6.84

ROE:20.12%

ROA:9.37%

PB:7.42

PE(LYR):49.82

Loading ...

Overview Company News Filings

Beneficial Ownership Change

Statement of acquisition of beneficial ownership by individuals

Beneficial Ownership Change

[Amend] Statement of acquisition of beneficial ownership by individuals

Beneficial Ownership Change

[Amend] Statement of acquisition of beneficial ownership by individuals

Beneficial Ownership Change

Statement of acquisition of beneficial ownership by individuals

Beneficial Ownership Change

[Amend] Statement of acquisition of beneficial ownership by individuals

Beneficial Ownership Change

[Amend] Statement of acquisition of beneficial ownership by individuals

Major Issues Report

[Amend] Current report, items 2.02 and 9.01

Major Issues Report

Current report, items 7.01 and 9.01

Quarterly Report

Quarterly report [Sections 13 or 15(d)]

Major Issues Report

Current report, items 7.01 and 9.01

Major Issues Report

Current report, items 2.02 and 9.01

Quarterly Report

Quarterly report [Sections 13 or 15(d)]

Major Issues Report

Current report, items 1.01 and 9.01

Major Issues Report

Current report, items 7.01 and 9.01

Statement Of Changes In Beneficial Ownership

Statement of changes in beneficial ownership of securities

Major Issues Report

Current report, item 5.07

Major Issues Report

Current report, items 2.02 and 9.01

Quarterly Report

Quarterly report [Sections 13 or 15(d)]

Correspondence

Correspondence

{"basename":"","ssrTDKData":{"titleTemplate":"%s - Tiger Brokers","title":"Tiger Brokers | Global Stocks, Options & Futures Trading App","description":"Tiger Brokers, one-stop investment in US stocks, SGX stocks, HK stocks, A-shares & other global assets. One of the best stock trading platforms in Singapore.","keywords":"tiger brokers,tiger trade,tiger brokers singapore,broker online,stock trading in singapore,share trading singapore,brokerage firm singapore,trading app,stock broker singapore,stock trading platforms,trading account","social":{"ogDescription":"Tiger Brokers, one-stop investment in US stocks, SGX stocks, HK stocks, A-shares & other global assets. One of the best stock trading platforms in Singapore.","ogImage":"https://c1.itigergrowtha.com/portal5/static/media/og-logo.0a0bd8dc.png","ogUrl":"https://www.etasphere.com/stock/KRYS/filings?page=11"},"companyName":"Tiger Brokers"},"pageData":{"isMobile":false,"isTiger":false,"isTTM":true,"region":"SGP","license":"TBSG","edition":"fundamental","symbol":"KRYS","isAnalysisPage":false},"__swrFallback__":{"@#url:\"https://hq.skytigris.cn/stock_info/detail/global\",params:#delay:false,,method:\"POST\",data:#items:@#symbol:\"KRYS\",,,,,undefined,":{"symbol":"KRYS","market":"US","secType":"STK","nameCN":"Krystal Biotech Inc.","latestPrice":340.77,"timestamp":1787593459826,"preClose":346.58,"halted":0,"volume":102015,"delay":0,"changeRate":-0.016763806336199442,"floatShares":23539300,"shares":29598836,"eps":7.965707,"marketStatus":"Trading","change":-5.81,"latestTime":"08-24 13:44:24 EDT","open":343.51,"high":346.5499,"low":337.09,"amount":34848533.13075,"amplitude":0.027295,"askPrice":341.18,"askSize":1,"bidPrice":340.44,"bidSize":8,"shortable":3,"etf":0,"ttmEps":7.965707,"tradingStatus":2,"nextMarketStatus":{"tag":"Post-Mkt","tradingStatus":3,"beginTime":1787601600000},"marketStatusCode":2,"adr":0,"adrRate":0,"listingDate":1505880000000,"exchange":"NASDAQ","adjPreClose":346.58,"preHourTrading":{"tag":"盘前","latestPrice":347.7,"preClose":346.58,"latestTime":"09:24 EDT","volume":9730,"amount":3372452.5415,"timestamp":1787577863932,"change":1.12,"changeRate":0.003232,"amplitude":0.015869},"postHourTrading":{"tag":"盘后","latestPrice":346.58,"preClose":346.58,"latestTime":"19:30 EDT","volume":78750,"amount":27292495.4745,"timestamp":1787355005656,"change":0,"changeRate":0,"amplitude":0},"volumeRatio":0.66622,"impliedVol":0.3845,"impliedVolPercentile":0.2151},"@#url:\"https://hq.skytigris.cn/stock_info/fundamental/all\",params:#delay:false,,method:\"POST\",data:#items:@#symbol:\"KRYS\",,,,,undefined,":{"symbol":"KRYS","floatShares":23539300,"roa":"9.37%","roe":"20.12%","lyrEps":6.84,"volumeRatio":0.66622,"shares":29598836,"dividePrice":0,"high":346.5499,"amplitude":0.027295,"preClose":346.58,"low":337.09,"week52Low":136.73,"pbRate":"7.42","psRate":"22.90","week52High":382.535,"institutionHeld":0,"latestPrice":340.77,"committee":0.777778,"eps":7.965707,"divideRate":0,"volume":102015,"delay":0,"ttmEps":7.965707,"open":343.51,"prevYearClose":246.54,"prevWeekClose":346.58,"prevMonthClose":341.12,"prevQuarterClose":371.67,"fiveDayClose":335.73,"twentyDayClose":351.82,"sixtyDayClose":310.3},"@#url:\"https://hq.skytigris.cn/fundamental/corporate_actions/details/KRYS\",params:#limit:5,,,undefined,":[{"market":"US","date":"2026-08-03","symbol":"KRYS","fiscalQuarterEnding":"2026/06","expectedEps":1.7,"name":null,"time":"Pre-MKt","type":"earning","dateTimestamp":1785729600000,"reportTimeType":"pre","actualEps":1.79},{"market":"US","date":"2026-05-04","symbol":"KRYS","fiscalQuarterEnding":"2026/03","expectedEps":1.45,"name":null,"time":"Pre-MKt","type":"earning","dateTimestamp":1777867200000,"reportTimeType":"pre","actualEps":1.83},{"market":"US","date":"2026-02-17","symbol":"KRYS","fiscalQuarterEnding":"2025/12","expectedEps":1.62,"name":null,"time":"Pre-MKt","type":"earning","dateTimestamp":1771304400000,"reportTimeType":"pre","actualEps":1.52},{"market":"US","date":"2026-01-11","symbol":"KRYS","fiscalQuarterEnding":null,"expectedEps":null,"name":null,"time":"Pre-MKt","type":"earning","dateTimestamp":1768107600000,"reportTimeType":"pre","actualEps":null},{"market":"US","date":"2025-11-03","symbol":"KRYS","fiscalQuarterEnding":"2025/09","expectedEps":1.12,"name":null,"time":"Pre-MKt","type":"earning","dateTimestamp":1762146000000,"reportTimeType":"pre","actualEps":2.66}],"@#url:\"https://hq.skytigris.cn/fundamental/dividend/history\",params:#symbol:\"KRYS\",market:\"US\",,,undefined,":[],"@#url:\"https://hq.skytigris.cn/fundamental/estimate/recommendation\",params:#symbol:\"KRYS\",market:\"US\",delay:false,,,undefined,":{"strongBuy":0.3846,"buy":0.5385,"hold":0.0769,"sell":0,"strongSell":0,"meanLabel":"BUY","meanPercent":0.5385,"analysts":13,"updateTime":1786766400000},"@#url:\"https://hq.skytigris.cn/value_analysis/stock/KRYS\",params:#withQuantilePoint:true,period:\"5year\",factor:\"peRate\",delay:false,algorithm:1,,,undefined,":{"brief":{"id":"KRYS","date":"2026-08-21","current":43.509007,"percent":0.732616,"low":-123.95382,"twenty":-23.698058,"median":26.827367,"eighty":50.439855,"high":470.599576,"avg":25.905337,"sd":96.821126,"marketCap":9975399708},"quantilePoints":[{"date":"2021-08-27","current":-24.688543,"twenty":-49.74713,"median":-39.304669,"eighty":-18.366962,"marketCap":1287927236},{"date":"2021-09-03","current":-24.931172,"twenty":-49.646847,"median":-39.216466,"eighty":-18.388495,"marketCap":1300584451},{"date":"2021-09-10","current":-24.688543,"twenty":-49.616178,"median":-39.194011,"eighty":-18.431559,"marketCap":1287927236},{"date":"2021-09-17","current":-25.195084,"twenty":-49.605002,"median":-39.194011,"eighty":-18.588744,"marketCap":1314351949},{"date":"2021-09-24","current":-23.960657,"twenty":-49.526812,"median":-39.170024,"eighty":-18.649982,"marketCap":1249955588},{"date":"2021-10-01","current":-22.939062,"twenty":-49.451445,"median":-39.094839,"eighty":-18.803765,"marketCap":1196662047},{"date":"2021-10-08","current":-21.96429,"twenty":-49.301275,"median":-39.010856,"eighty":-19.133337,"marketCap":1145811127},{"date":"2021-10-15","current":-20.738376,"twenty":-49.204717,"median":-38.949071,"eighty":-19.258353,"marketCap":1081858878},{"date":"2021-10-22","current":-23.117841,"twenty":-49.133851,"median":-38.916338,"eighty":-19.357444,"marketCap":1205988417},{"date":"2021-10-29","current":-21.321537,"twenty":-49.101247,"median":-38.817644,"eighty":-19.544974,"marketCap":1112280607},{"date":"2021-11-05","current":-21.840847,"twenty":-49.044258,"median":-38.756093,"eighty":-19.7047,"marketCap":1139371491},{"date":"2021-11-12","current":-18.1661,"twenty":-48.981858,"median":-38.628777,"eighty":-19.142222,"marketCap":1056304240},{"date":"2021-11-19","current":-20.028604,"twenty":-48.927861,"median":-38.546893,"eighty":-18.827374,"marketCap":1164603222},{"date":"2021-11-26","current":-15.225104,"twenty":-48.904406,"median":-38.463296,"eighty":-18.643824,"marketCap":885294143},{"date":"2021-12-03","current":-29.173669,"twenty":-48.882674,"median":-38.43672,"eighty":-18.726968,"marketCap":1696361350},{"date":"2021-12-10","current":-30.64713,"twenty":-48.864761,"median":-38.327334,"eighty":-18.774187,"marketCap":1782038681},{"date":"2021-12-17","current":-30.831313,"twenty":-48.857578,"median":-38.211464,"eighty":-18.814077,"marketCap":1792748347},{"date":"2021-12-23","current":-30.981229,"twenty":-48.81044,"median":-38.116975,"eighty":-18.858441,"marketCap":1801465518},{"date":"2021-12-31","current":-29.9618,"twenty":-48.685744,"median":-38.062665,"eighty":-18.99677,"marketCap":1742188759},{"date":"2022-01-07","current":-27.503176,"twenty":-48.572435,"median":-38.016003,"eighty":-19.181169,"marketCap":1599227166},{"date":"2022-01-14","current":-26.676496,"twenty":-48.505452,"median":-37.928,"eighty":-19.232428,"marketCap":1551158198},{"date":"2022-01-21","current":-23.682457,"twenty":-48.470858,"median":-37.86578,"eighty":-19.292847,"marketCap":1377063853},{"date":"2022-01-28","current":-23.02711,"twenty":-48.443754,"median":-37.79723,"eighty":-19.420475,"marketCap":1338957365},{"date":"2022-02-04","current":-24.367788,"twenty":-48.384784,"median":-37.713725,"eighty":-19.61603,"marketCap":1416913774},{"date":"2022-02-11","current":-27.858691,"twenty":-48.353986,"median":-37.628943,"eighty":-19.746268,"marketCap":1619899313},{"date":"2022-02-18","current":-26.068265,"twenty":-48.294422,"median":-37.527971,"eighty":-19.799528,"marketCap":1515791392},{"date":"2022-02-25","current":-26.770729,"twenty":-48.279712,"median":-37.476042,"eighty":-19.820386,"marketCap":1556637562},{"date":"2022-03-04","current":-20.780274,"twenty":-48.170794,"median":-37.375723,"eighty":-19.874216,"marketCap":1445683674},{"date":"2022-03-11","current":-23.490587,"twenty":-48.163532,"median":-37.319356,"eighty":-20.028604,"marketCap":1634240150},{"date":"2022-03-18","current":-25.686376,"twenty":-48.135113,"median":-37.241884,"eighty":-20.040286,"marketCap":1787001145},{"date":"2022-03-25","current":-23.316663,"twenty":-48.134488,"median":-37.20653,"eighty":-20.244009,"marketCap":1622140269},{"date":"2022-04-01","current":-25.671882,"twenty":-47.972128,"median":-37.140116,"eighty":-20.291429,"marketCap":1785992822},{"date":"2022-04-08","current":-24.639209,"twenty":-47.952591,"median":-36.813313,"eighty":-20.447526,"marketCap":1714149780},{"date":"2022-04-14","current":-26.266122,"twenty":-47.854585,"median":-36.709334,"eighty":-20.591978,"marketCap":1827334081},{"date":"2022-04-22","current":-25.113876,"twenty":-47.822023,"median":-36.538643,"eighty":-20.716319,"marketCap":1747172371},{"date":"2022-04-29","current":-21.961507,"twenty":-47.811315,"median":-36.49065,"eighty":-20.771894,"marketCap":1527862031},{"date":"2022-05-06","current":-20.356335,"twenty":-47.795803,"median":-36.453959,"eighty":-20.771894,"marketCap":1416190215},{"date":"2022-05-13","current":-13.934316,"twenty":-47.750551,"median":-36.327794,"eighty":-20.343354,"marketCap":1445309080},{"date":"2022-05-20","current":-14.591735,"twenty":-47.740072,"median":-36.233637,"eighty":-19.997726,"marketCap":1513498547},{"date":"2022-05-27","current":-14.893258,"twenty":-47.602075,"median":-36.204791,"eighty":-19.7047,"marketCap":1544773415},{"date":"2022-06-03","current":-15.310942,"twenty":-47.510413,"median":-36.177424,"eighty":-19.24539,"marketCap":1588096799},{"date":"2022-06-10","current":-13.810741,"twenty":-47.432166,"median":-36.136288,"eighty":-18.814077,"marketCap":1432491511},{"date":"2022-06-17","current":-13.716824,"twenty":-47.389756,"median":-36.049958,"eighty":-18.612985,"marketCap":1422750159},{"date":"2022-06-24","current":-16.934717,"twenty":-47.377399,"median":-35.980519,"eighty":-18.375575,"marketCap":1756519655},{"date":"2022-07-01","current":-16.67521,"twenty":-47.361475,"median":-35.968421,"eighty":-18.014122,"marketCap":1729602760},{"date":"2022-07-08","current":-18.064192,"twenty":-47.320353,"median":-35.870695,"eighty":-17.922179,"marketCap":1873672236},{"date":"2022-07-15","current":-17.898602,"twenty":-47.198689,"median":-35.678732,"eighty":-17.879132,"marketCap":1856496693},{"date":"2022-07-22","current":-17.298028,"twenty":-47.051002,"median":-35.584271,"eighty":-17.828596,"marketCap":1794203308},{"date":"2022-07-29","current":-17.938146,"twenty":-47.0077,"median":-35.480795,"eighty":-17.817212,"marketCap":1860598316},{"date":"2022-08-05","current":-20.288542,"twenty":-46.920258,"median":-35.417625,"eighty":-17.801224,"marketCap":2104388478},{"date":"2022-08-12","current":-17.625319,"twenty":-46.853686,"median":-35.366012,"eighty":-17.729767,"marketCap":2035177959},{"date":"2022-08-19","current":-16.951867,"twenty":-46.752193,"median":-35.323413,"eighty":-17.686971,"marketCap":1957415169},{"date":"2022-08-26","current":-15.629413,"twenty":-46.706201,"median":-35.308589,"eighty":-17.612613,"marketCap":1804712661},{"date":"2022-09-02","current":-15.718317,"twenty":-46.676374,"median":-35.240563,"eighty":-17.403682,"marketCap":1814978376},{"date":"2022-09-09","current":-15.744989,"twenty":-46.578516,"median":-35.087812,"eighty":-17.243655,"marketCap":1818058091},{"date":"2022-09-16","current":-15.229342,"twenty":-46.557824,"median":-35.036637,"eighty":-17.102287,"marketCap":1758516945},{"date":"2022-09-23","current":-15.044866,"twenty":-46.55592,"median":-35.010504,"eighty":-16.988902,"marketCap":1737215587},{"date":"2022-09-30","current":-15.491611,"twenty":-46.49581,"median":-34.885868,"eighty":-16.891857,"marketCap":1788800803},{"date":"2022-10-07","current":-14.707028,"twenty":-46.461793,"median":-34.834361,"eighty":-16.822027,"marketCap":1698205870},{"date":"2022-10-14","current":-14.671467,"twenty":-46.418331,"median":-34.793122,"eighty":-16.63712,"marketCap":1694099584},{"date":"2022-10-21","current":-15.502724,"twenty":-46.353136,"median":-34.700752,"eighty":-16.49856,"marketCap":1790084018},{"date":"2022-10-28","current":-17.287482,"twenty":-46.309342,"median":-34.636468,"eighty":-16.468869,"marketCap":1996168242},{"date":"2022-11-04","current":-16.271748,"twenty":-46.234543,"median":-34.582951,"eighty":-16.431776,"marketCap":1878882451},{"date":"2022-11-11","current":-15.210937,"twenty":-46.168419,"median":-34.435035,"eighty":-16.368613,"marketCap":1973299666},{"date":"2022-11-18","current":-15.355822,"twenty":-46.157554,"median":-34.313591,"eighty":-16.330309,"marketCap":1992095448},{"date":"2022-11-25","current":-15.62376,"twenty":-46.086628,"median":-34.283013,"eighty":-16.267534,"marketCap":2026854771},{"date":"2022-12-02","current":-15.381624,"twenty":-46.063708,"median":-34.2247,"eighty":-16.23032,"marketCap":1995442642},{"date":"2022-12-09","current":-14.097506,"twenty":-46.034552,"median":-34.199021,"eighty":-16.194819,"marketCap":1828855366},{"date":"2022-12-16","current":-15.846049,"twenty":-46.009864,"median":-34.117009,"eighty":-16.105287,"marketCap":2055692136},{"date":"2022-12-23","current":-15.208952,"twenty":-45.976836,"median":-34.094867,"eighty":-16.032251,"marketCap":1973042189},{"date":"2022-12-30","current":-15.722996,"twenty":-45.957195,"median":-34.006336,"eighty":-15.997799,"marketCap":2039728595},{"date":"2023-01-06","current":-16.445436,"twenty":-45.957195,"median":-34.006336,"eighty":-16.026688,"marketCap":2133450030},{"date":"2023-01-13","current":-16.463299,"twenty":-45.957195,"median":-34.006336,"eighty":-16.052385,"marketCap":2135767318},{"date":"2023-01-20","current":-16.121926,"twenty":-45.957195,"median":-34.006336,"eighty":-16.075746,"marketCap":2091481365},{"date":"2023-01-27","current":-16.715359,"twenty":-45.957195,"median":-34.006336,"eighty":-16.115059,"marketCap":2168466830},{"date":"2023-02-03","current":-15.919484,"twenty":-45.957195,"median":-34.006336,"eighty":-16.177016,"marketCap":2065218765},{"date":"2023-02-10","current":-15.238723,"twenty":-45.957195,"median":-34.006336,"eighty":-16.177016,"marketCap":1976904336},{"date":"2023-02-17","current":-15.530478,"twenty":-45.957195,"median":-34.006336,"eighty":-16.177016,"marketCap":2014753377},{"date":"2023-02-24","current":-15.572157,"twenty":-45.957195,"median":-34.006336,"eighty":-16.177016,"marketCap":2020160383},{"date":"2023-03-03","current":-14.548071,"twenty":-45.957195,"median":-34.006336,"eighty":-16.177016,"marketCap":2036366246},{"date":"2023-03-10","current":-13.465801,"twenty":-45.957195,"median":-34.006336,"eighty":-16.177016,"marketCap":1884875437},{"date":"2023-03-17","current":-13.684832,"twenty":-45.957195,"median":-34.006336,"eighty":-16.177016,"marketCap":1915534292},{"date":"2023-03-24","current":-14.336403,"twenty":-45.957195,"median":-34.006336,"eighty":-16.177016,"marketCap":2006737942},{"date":"2023-03-31","current":-14.735812,"twenty":-45.953031,"median":-33.990713,"eighty":-16.121365,"marketCap":2062645264},{"date":"2023-04-06","current":-14.458549,"twenty":-45.953031,"median":-33.990713,"eighty":-16.121365,"marketCap":2023835412},{"date":"2023-04-14","current":-16.381934,"twenty":-45.957195,"median":-34.006336,"eighty":-16.215813,"marketCap":2293061223},{"date":"2023-04-21","current":-16.077951,"twenty":-45.957195,"median":-34.006336,"eighty":-16.227249,"marketCap":2250511167},{"date":"2023-04-28","current":-15.451561,"twenty":-45.957195,"median":-34.006336,"eighty":-16.227249,"marketCap":2162832263},{"date":"2023-05-05","current":-15.140209,"twenty":-45.957195,"median":-34.006336,"eighty":-16.227249,"marketCap":2119250690},{"date":"2023-05-12","current":-17.21991,"twenty":-45.957195,"median":-34.006336,"eighty":-16.238247,"marketCap":2329974338},{"date":"2023-05-19","current":-16.674578,"twenty":-45.976836,"median":-34.094867,"eighty":-16.310866,"marketCap":2256187088},{"date":"2023-05-24","current":-24.238106,"twenty":-45.983985,"median":-34.102678,"eighty":-16.350103,"marketCap":3279585403},{"date":"2023-06-23","current":-24.404943,"twenty":-46.067599,"median":-34.263206,"eighty":-16.497343,"marketCap":3302159566},{"date":"2023-06-30","current":-23.534137,"twenty":-46.068896,"median":-34.273109,"eighty":-16.557943,"marketCap":3184333447},{"date":"2023-07-07","current":-24.687751,"twenty":-46.068896,"median":-34.273109,"eighty":-16.674578,"marketCap":3340425525},{"date":"2023-07-14","current":-25.51583,"twenty":-46.068896,"median":-34.273109,"eighty":-16.67521,"marketCap":3452470456},{"date":"2023-07-21","current":-25.447272,"twenty":-46.068896,"median":-34.273109,"eighty":-16.67521,"marketCap":3443194084},{"date":"2023-07-28","current":-25.0364,"twenty":-46.068896,"median":-34.273109,"eighty":-16.67521,"marketCap":3387600119},{"date":"2023-08-04","current":-25.721876,"twenty":-46.068896,"median":-34.273109,"eighty":-16.67521,"marketCap":3480349850},{"date":"2023-08-11","current":-24.078633,"twenty":-46.068896,"median":-34.273109,"eighty":-16.793842,"marketCap":3380856756},{"date":"2023-08-18","current":-23.486486,"twenty":-46.068896,"median":-34.273109,"eighty":-16.891857,"marketCap":3297714050},{"date":"2023-08-25","current":-24.754517,"twenty":-46.068896,"median":-34.273109,"eighty":-17.009655,"marketCap":3475757016},{"date":"2023-09-01","current":-24.818318,"twenty":-46.068896,"median":-34.273109,"eighty":-17.21991,"marketCap":3484715152},{"date":"2023-09-08","current":-24.162371,"twenty":-46.068896,"median":-34.273109,"eighty":-17.243655,"marketCap":3392614310},{"date":"2023-09-15","current":-23.725737,"twenty":-46.068896,"median":-34.273109,"eighty":-17.287482,"marketCap":3331307063},{"date":"2023-09-22","current":-23.679881,"twenty":-46.068896,"median":-34.273109,"eighty":-17.468482,"marketCap":3324868402},{"date":"2023-09-29","current":-23.506424,"twenty":-46.068896,"median":-34.273109,"eighty":-17.574836,"marketCap":3300513468},{"date":"2023-10-06","current":-22.872408,"twenty":-46.068896,"median":-34.273109,"eighty":-17.725597,"marketCap":3211491985},{"date":"2023-10-13","current":-22.100823,"twenty":-46.068896,"median":-34.273109,"eighty":-17.898602,"marketCap":3103154520},{"date":"2023-10-20","current":-21.931354,"twenty":-46.068896,"median":-34.273109,"eighty":-17.898602,"marketCap":3079359470},{"date":"2023-10-27","current":-23.528355,"twenty":-46.122091,"median":-34.313591,"eighty":-17.88229,"marketCap":3303592827},{"date":"2023-11-03","current":-23.735706,"twenty":-46.122091,"median":-34.313591,"eighty":-17.88229,"marketCap":3332706771},{"date":"2023-11-10","current":-90.829454,"twenty":-46.392253,"median":-34.313591,"eighty":-17.88229,"marketCap":2707807680},{"date":"2023-11-17","current":-93.043422,"twenty":-46.570239,"median":-34.313591,"eighty":-17.88229,"marketCap":2773810492},{"date":"2023-11-24","current":-97.329437,"twenty":-46.831104,"median":-34.313591,"eighty":-17.88229,"marketCap":2901585167},{"date":"2023-12-01","current":-98.616187,"twenty":-47.298789,"median":-34.313591,"eighty":-17.88229,"marketCap":2939945775},{"date":"2023-12-08","current":-97.830891,"twenty":-47.510413,"median":-34.313591,"eighty":-17.887727,"marketCap":2916534522},{"date":"2023-12-15","current":-110.017176,"twenty":-47.813488,"median":-34.313591,"eighty":-17.887727,"marketCap":3279832052},{"date":"2023-12-22","current":-110.471323,"twenty":-48.134738,"median":-34.371057,"eighty":-17.887727,"marketCap":3293371090},{"date":"2023-12-29","current":-120.878865,"twenty":-48.236145,"median":-34.428523,"eighty":-17.88229,"marketCap":3603640720},{"date":"2024-01-05","current":-113.659816,"twenty":-48.384784,"median":-34.371057,"eighty":-17.876852,"marketCap":3388426422},{"date":"2024-01-12","current":-118.295902,"twenty":-48.713256,"median":-34.371057,"eighty":-17.876852,"marketCap":3526637439},{"date":"2024-01-19","current":-121.635777,"twenty":-48.895713,"median":-34.313591,"eighty":-17.871415,"marketCap":3626205784},{"date":"2024-01-26","current":-114.189654,"twenty":-49.115343,"median":-34.371057,"eighty":-17.876852,"marketCap":3404221967},{"date":"2024-02-02","current":-105.551395,"twenty":-49.584797,"median":-34.371057,"eighty":-17.876852,"marketCap":3146698174},{"date":"2024-02-09","current":-105.04994,"twenty":-49.865711,"median":-34.371057,"eighty":-17.876852,"marketCap":3131748819},{"date":"2024-02-16","current":-107.27337,"twenty":-50.169453,"median":-34.371057,"eighty":-17.876852,"marketCap":3198033695},{"date":"2024-02-23","current":-105.929851,"twenty":-50.309576,"median":-34.371057,"eighty":-17.876852,"marketCap":3157980706},{"date":"2024-03-01","current":412.717112,"twenty":-50.298536,"median":-34.214644,"eighty":-17.670729,"marketCap":4511823473},{"date":"2024-03-08","current":438.623542,"twenty":-50.298536,"median":-34.11049,"eighty":-17.456094,"marketCap":4795032559},{"date":"2024-03-15","current":444.731351,"twenty":-50.298536,"median":-34.058413,"eighty":-17.243655,"marketCap":4861803133},{"date":"2024-03-22","current":439.451719,"twenty":-50.298536,"median":-34.058413,"eighty":-17.080779,"marketCap":4804086196},{"date":"2024-03-28","current":458.603326,"twenty":-50.298536,"median":-33.969882,"eighty":-16.958091,"marketCap":5013451555},{"date":"2024-04-05","current":465.539366,"twenty":-50.309576,"median":-33.719912,"eighty":-16.796553,"marketCap":5089276348},{"date":"2024-04-12","current":469.347566,"twenty":-50.309576,"median":-33.084571,"eighty":-16.674704,"marketCap":5130907587},{"date":"2024-04-19","current":427.692121,"twenty":-50.309576,"median":-32.75328,"eighty":-16.501802,"marketCap":4675530271},{"date":"2024-04-26","current":406.068851,"twenty":-50.298536,"median":-32.569008,"eighty":-16.436221,"marketCap":4439144676},{"date":"2024-05-03","current":417.93687,"twenty":-50.298536,"median":-32.4284,"eighty":-16.38783,"marketCap":4568885865},{"date":"2024-05-10","current":79.30624,"twenty":-50.298536,"median":-32.023135,"eighty":-16.247299,"marketCap":4533223973},{"date":"2024-05-17","current":81.826793,"twenty":-50.298536,"median":-31.168135,"eighty":-16.221187,"marketCap":4677301303},{"date":"2024-05-24","current":81.746855,"twenty":-50.298536,"median":-30.861296,"eighty":-16.086794,"marketCap":4672731952},{"date":"2024-05-31","current":80.737634,"twenty":-50.298536,"median":-30.656782,"eighty":-16.021314,"marketCap":4615043904},{"date":"2024-06-07","current":82.77606,"twenty":-50.298536,"median":-30.573158,"eighty":-15.931392,"marketCap":4731562339},{"date":"2024-06-14","current":91.289483,"twenty":-50.309576,"median":-30.424411,"eighty":-15.870101,"marketCap":5218198156},{"date":"2024-06-21","current":85.538925,"twenty":-50.320616,"median":-30.308863,"eighty":-15.845006,"marketCap":4889490512},{"date":"2024-06-28","current":91.364425,"twenty":-50.243436,"median":-30.172403,"eighty":-15.832659,"marketCap":5222481922},{"date":"2024-07-05","current":88.711475,"twenty":-50.030354,"median":-30.064599,"eighty":-15.745878,"marketCap":5070836606},{"date":"2024-07-12","current":99.12593,"twenty":-49.707017,"median":-29.906192,"eighty":-15.692535,"marketCap":5666137288},{"date":"2024-07-15","current":101.486607,"twenty":-49.631513,"median":-29.886841,"eighty":-15.684533,"marketCap":5801075917},{"date":"2024-08-02","current":99.313285,"twenty":-48.900059,"median":-28.925237,"eighty":-15.650295,"marketCap":5676846703},{"date":"2024-08-09","current":48.914679,"twenty":-48.878328,"median":-27.982907,"eighty":-15.581763,"marketCap":5182021081},{"date":"2024-08-16","current":52.605585,"twenty":-48.878328,"median":-27.374676,"eighty":-15.548992,"marketCap":5573035701},{"date":"2024-08-23","current":53.565601,"twenty":-48.878328,"median":-26.655115,"eighty":-15.520349,"marketCap":5674739724},{"date":"2024-08-30","current":52.941862,"twenty":-48.857233,"median":-26.47628,"eighty":-15.490386,"marketCap":5608660839},{"date":"2024-09-06","current":50.457754,"twenty":-48.630719,"median":-26.166781,"eighty":-15.457456,"marketCap":5345494497},{"date":"2024-09-13","current":53.055762,"twenty":-48.460798,"median":-26.068265,"eighty":-15.413334,"marketCap":5620727418},{"date":"2024-09-20","current":50.029273,"twenty":-48.192578,"median":-25.740727,"eighty":-15.39115,"marketCap":5300101176},{"date":"2024-09-27","current":48.383145,"twenty":-48.140297,"median":-25.686376,"eighty":-15.36671,"marketCap":5125710379},{"date":"2024-10-04","current":47.710592,"twenty":-48.140297,"median":-25.447272,"eighty":-15.321442,"marketCap":5054460103},{"date":"2024-10-11","current":46.956682,"twenty":-48.140297,"median":-25.385616,"eighty":-15.281299,"marketCap":4974590842},{"date":"2024-10-18","current":47.951952,"twenty":-48.140297,"median":-25.271568,"eighty":-15.240109,"marketCap":5080029759},{"date":"2024-10-25","current":47.451605,"twenty":-48.140297,"median":-25.171213,"eighty":-15.224652,"marketCap":5027023001},{"date":"2024-10-31","current":47.602116,"twenty":-48.140297,"median":-25.096704,"eighty":-15.205029,"marketCap":5042968123},{"date":"2024-11-08","current":101.841511,"twenty":-48.146106,"median":-24.998383,"eighty":-15.130658,"marketCap":5333643626},{"date":"2024-11-15","current":97.415291,"twenty":-47.879086,"median":-24.91462,"eighty":-15.077305,"marketCap":5101833609},{"date":"2024-11-22","current":100.106169,"twenty":-47.470274,"median":-24.817537,"eighty":-15.048069,"marketCap":5242760294},{"date":"2024-11-29","current":108.414943,"twenty":-46.981573,"median":-24.731231,"eighty":-14.930248,"marketCap":5677907386},{"date":"2024-12-06","current":98.716797,"twenty":-46.556682,"median":-24.688543,"eighty":-14.766359,"marketCap":5169996108},{"date":"2024-12-13","current":95.224147,"twenty":-45.957195,"median":-24.651106,"eighty":-14.731394,"marketCap":4987079023},{"date":"2024-12-20","current":88.32122,"twenty":-45.41369,"median":-24.553429,"eighty":-14.65839,"marketCap":4625558934},{"date":"2024-12-27","current":88.134506,"twenty":-45.180681,"median":-24.428361,"eighty":-14.599772,"marketCap":4615780348},{"date":"2025-01-03","current":85.943362,"twenty":-44.758848,"median":-24.355772,"eighty":-14.550543,"marketCap":4501025762},{"date":"2025-01-10","current":86.036719,"twenty":-44.038175,"median":-24.273244,"eighty":-14.442688,"marketCap":4505915055},{"date":"2025-01-17","current":79.523695,"twenty":-43.941673,"median":-24.162371,"eighty":-14.343029,"marketCap":4164814955},{"date":"2025-01-24","current":85.152573,"twenty":-43.692807,"median":-24.117438,"eighty":-14.205806,"marketCap":4459610572},{"date":"2025-01-31","current":85.707224,"twenty":-43.431749,"median":-24.033689,"eighty":-14.048246,"marketCap":4488658726},{"date":"2025-02-07","current":88.447527,"twenty":-43.23416,"median":-23.960657,"eighty":-13.7871,"marketCap":4632173860},{"date":"2025-02-14","current":85.531493,"twenty":-43.090832,"median":-23.925397,"eighty":-13.666581,"marketCap":4479455351},{"date":"2025-02-21","current":59.002075,"twenty":-42.90401,"median":-23.862754,"eighty":-13.491569,"marketCap":5260565964},{"date":"2025-02-28","current":56.007062,"twenty":-42.713839,"median":-23.782357,"eighty":-13.200775,"marketCap":4993533621},{"date":"2025-03-07","current":57.809885,"twenty":-42.402497,"median":-23.70101,"eighty":-12.237878,"marketCap":5154271536},{"date":"2025-03-14","current":57.30587,"twenty":-42.130534,"median":-23.62904,"eighty":47.292958,"marketCap":5109334054},{"date":"2025-03-21","current":60.937363,"twenty":-42.130534,"median":-23.531246,"eighty":47.579878,"marketCap":5433114371},{"date":"2025-03-28","current":59.044076,"twenty":-42.130534,"median":-23.480942,"eighty":47.967138,"marketCap":5264310754},{"date":"2025-04-04","current":57.551416,"twenty":-42.130534,"median":-23.298076,"eighty":48.348975,"marketCap":5131226674},{"date":"2025-04-11","current":51.903862,"twenty":-42.117793,"median":-23.201379,"eighty":48.571894,"marketCap":4627696430},{"date":"2025-04-17","current":53.212363,"twenty":-42.108146,"median":-23.107672,"eighty":48.798067,"marketCap":4744361046},{"date":"2025-04-25","current":54.81554,"twenty":-41.734951,"median":-23.01592,"eighty":49.395229,"marketCap":4887298760},{"date":"2025-05-02","current":53.703801,"twenty":-41.655942,"median":-22.970987,"eighty":50.025476,"marketCap":4788177221},{"date":"2025-05-09","current":31.978315,"twenty":-41.429199,"median":-22.885854,"eighty":50.376397,"marketCap":3964031935},{"date":"2025-05-16","current":30.383712,"twenty":-41.221012,"median":-22.743811,"eighty":50.376397,"marketCap":3766364964},{"date":"2025-05-23","current":29.208742,"twenty":-41.044653,"median":-22.613428,"eighty":50.376397,"marketCap":3620715617},{"date":"2025-05-30","current":29.283343,"twenty":-40.746006,"median":-22.521507,"eighty":50.376397,"marketCap":3629963194},{"date":"2025-06-06","current":30.917578,"twenty":-40.38983,"median":-22.291149,"eighty":50.376397,"marketCap":3832542941},{"date":"2025-06-13","current":32.715003,"twenty":-40.072518,"median":-22.123914,"eighty":50.376397,"marketCap":4055351764},{"date":"2025-06-20","current":30.794019,"twenty":-39.896405,"median":-21.96429,"eighty":50.427923,"marketCap":3817226641},{"date":"2025-06-27","current":33.239543,"twenty":-39.625462,"median":-21.730175,"eighty":50.427923,"marketCap":4120373794},{"date":"2025-07-03","current":33.356108,"twenty":-39.364195,"median":-21.494087,"eighty":50.427923,"marketCap":4134823134},{"date":"2025-07-11","current":34.908748,"twenty":-39.043119,"median":-20.823509,"eighty":50.427923,"marketCap":4327288343},{"date":"2025-07-18","current":35.00433,"twenty":-38.925872,"median":-20.291429,"eighty":50.427923,"marketCap":4339136802},{"date":"2025-07-25","current":34.969361,"twenty":-38.619101,"median":-19.41116,"eighty":50.427923,"marketCap":4334802000},{"date":"2025-08-01","current":35.871571,"twenty":-38.042013,"median":-18.594438,"eighty":50.427923,"marketCap":4446639891},{"date":"2025-08-08","current":26.847093,"twenty":-37.221287,"median":-18.227311,"eighty":50.427923,"marketCap":3939139714},{"date":"2025-08-15","current":29.654103,"twenty":-36.653092,"median":-18.098793,"eighty":50.427923,"marketCap":4350998333},{"date":"2025-08-22","current":28.740789,"twenty":-35.584271,"median":-17.921336,"eighty":50.427923,"marketCap":4216992331},{"date":"2025-08-29","current":29.738925,"twenty":-35.240563,"median":-17.755255,"eighty":50.427923,"marketCap":4363443815},{"date":"2025-09-05","current":29.539693,"twenty":-34.696878,"median":-17.592136,"eighty":50.433889,"marketCap":4334211404},{"date":"2025-09-12","current":28.476461,"twenty":-34.438576,"median":-17.291927,"eighty":50.427923,"marketCap":4178208737},{"date":"2025-09-19","current":31.681937,"twenty":-34.199021,"median":-17.21991,"eighty":50.427923,"marketCap":4648532178},{"date":"2025-09-26","current":31.788457,"twenty":-34.094867,"median":-17.002987,"eighty":50.427923,"marketCap":4664161388},{"date":"2025-10-03","current":35.840179,"twenty":-33.876143,"median":-16.828443,"eighty":50.427923,"marketCap":5258650217},{"date":"2025-10-10","current":37.234807,"twenty":-33.719912,"median":-16.705053,"eighty":50.427923,"marketCap":5463277093},{"date":"2025-10-17","current":37.149985,"twenty":-33.016871,"median":-16.538461,"eighty":50.427923,"marketCap":5450831611},{"date":"2025-10-24","current":36.779137,"twenty":-32.638872,"median":-16.443452,"eighty":50.427923,"marketCap":5396418807},{"date":"2025-10-31","current":37.29793,"twenty":-32.397154,"median":-16.416938,"eighty":50.427923,"marketCap":5472538847},{"date":"2025-11-07","current":29.152048,"twenty":-31.194173,"median":-16.271748,"eighty":50.427923,"marketCap":5798633874},{"date":"2025-11-14","current":29.332818,"twenty":-31.194173,"median":-16.227296,"eighty":50.427923,"marketCap":5834590797},{"date":"2025-11-21","current":29.772351,"twenty":-31.194173,"median":-16.112375,"eighty":50.427923,"marketCap":5922018317},{"date":"2025-11-28","current":31.780499,"twenty":-30.980657,"median":-16.027677,"eighty":50.427923,"marketCap":6321459142},{"date":"2025-12-05","current":32.357797,"twenty":-30.64713,"median":-15.980718,"eighty":50.427923,"marketCap":6436289317},{"date":"2025-12-12","current":35.97538,"twenty":-30.424398,"median":-15.87898,"eighty":50.427923,"marketCap":7155862751},{"date":"2025-12-19","current":34.02117,"twenty":-30.197382,"median":-15.845006,"eighty":50.427923,"marketCap":6767151009},{"date":"2025-12-26","current":36.633586,"twenty":-29.983216,"median":-15.758324,"eighty":50.427923,"marketCap":7286786549},{"date":"2026-01-02","current":35.941121,"twenty":-29.8847,"median":-15.724981,"eighty":50.427923,"marketCap":7149048334},{"date":"2026-01-09","current":36.286624,"twenty":-29.460652,"median":-15.682755,"eighty":50.427923,"marketCap":7217772454},{"date":"2026-01-16","current":41.112012,"twenty":-28.235623,"median":-15.62376,"eighty":50.427923,"marketCap":8177590333},{"date":"2026-01-23","current":42.149252,"twenty":-27.858691,"median":-15.577864,"eighty":50.427923,"marketCap":8383907680},{"date":"2026-01-30","current":40.722774,"twenty":-26.88636,"median":-15.547362,"eighty":50.427923,"marketCap":8100166957},{"date":"2026-02-06","current":39.017123,"twenty":-26.605562,"median":-15.519727,"eighty":50.427923,"marketCap":7760895985},{"date":"2026-02-13","current":39.399072,"twenty":-26.382071,"median":-15.488799,"eighty":50.427923,"marketCap":7836869484},{"date":"2026-02-20","current":37.486606,"twenty":-26.153796,"median":-15.451561,"eighty":50.427923,"marketCap":7678419084},{"date":"2026-02-27","current":39.440357,"twenty":-26.033998,"median":-15.411394,"eighty":50.427923,"marketCap":8078607752},{"date":"2026-03-06","current":37.152656,"twenty":-25.737103,"median":-15.381624,"eighty":50.427923,"marketCap":7610015762},{"date":"2026-03-13","current":35.865379,"twenty":-25.617531,"median":-15.364972,"eighty":50.427923,"marketCap":7346341417},{"date":"2026-03-20","current":36.820133,"twenty":-25.42442,"median":-15.310942,"eighty":50.427923,"marketCap":7541904762},{"date":"2026-03-27","current":35.878223,"twenty":-25.295047,"median":-15.276947,"eighty":50.427923,"marketCap":7348972314},{"date":"2026-04-02","current":36.950003,"twenty":-25.256945,"median":-15.240456,"eighty":50.427923,"marketCap":7568506053},{"date":"2026-04-10","current":37.123952,"twenty":-25.141307,"median":-15.225104,"eighty":50.427923,"marketCap":7604136264},{"date":"2026-04-17","current":37.947396,"twenty":-25.057569,"median":-15.189335,"eighty":50.427923,"marketCap":7772803088},{"date":"2026-04-24","current":38.519352,"twenty":-24.972594,"median":-15.129325,"eighty":50.427923,"marketCap":7889957357},{"date":"2026-05-01","current":37.688723,"twenty":-24.896471,"median":-15.076322,"eighty":50.427923,"marketCap":7719818745},{"date":"2026-05-08","current":38.868789,"twenty":-24.754517,"median":-15.046205,"eighty":50.427923,"marketCap":8746643605},{"date":"2026-05-15","current":41.436461,"twenty":-24.71162,"median":-14.885442,"eighty":50.427923,"marketCap":9324446822},{"date":"2026-05-22","current":39.855247,"twenty":-24.687751,"median":-14.75842,"eighty":50.427923,"marketCap":8968626167},{"date":"2026-05-29","current":40.650439,"twenty":-24.589706,"median":-14.724723,"eighty":50.433889,"marketCap":9147568286},{"date":"2026-06-05","current":40.32162,"twenty":-24.509764,"median":-14.651245,"eighty":50.427923,"marketCap":9073574099},{"date":"2026-06-12","current":42.123575,"twenty":-24.404943,"median":-14.589718,"eighty":50.427923,"marketCap":9479068143},{"date":"2026-06-18","current":44.758714,"twenty":-24.31589,"median":-14.513819,"eighty":50.427923,"marketCap":10072053434},{"date":"2026-06-26","current":47.152151,"twenty":-24.238612,"median":-14.375858,"eighty":50.433889,"marketCap":10610648577},{"date":"2026-07-02","current":48.678344,"twenty":-24.145435,"median":-14.256659,"eighty":50.433889,"marketCap":10954087734},{"date":"2026-07-10","current":48.633803,"twenty":-24.050657,"median":-14.126765,"eighty":50.433889,"marketCap":10944064617},{"date":"2026-07-17","current":44.775745,"twenty":-23.969929,"median":-13.91578,"eighty":50.433889,"marketCap":10075885803},{"date":"2026-07-24","current":42.903702,"twenty":-23.934265,"median":-13.700828,"eighty":50.433889,"marketCap":9654620090},{"date":"2026-07-31","current":48.058697,"twenty":-23.864621,"median":-13.579918,"eighty":50.439855,"marketCap":10814648488},{"date":"2026-08-07","current":39.555579,"twenty":-23.784432,"median":-13.311498,"eighty":50.439855,"marketCap":9551248388},{"date":"2026-08-14","current":40.24816,"twenty":-23.719756,"median":-12.587349,"eighty":50.439855,"marketCap":9718481812},{"date":"2026-08-21","current":41.312161,"twenty":-23.698058,"median":26.827367,"eighty":50.439855,"marketCap":9975399708}],"updateTime":1787552561704},"$inf$@#url:\"https://stock-news.skytigris.cn/v3/notice/important/events/list\",params:#symbol:\"KRYS\",pageSize:20,pageCount:11,market:\"us\",,,undefined,":[{"items":[{"cdn_pdf":false,"hasAttachments":true,"id":"9098814","market":"us","labels":[],"media":"sec.gov","original_id":"AN117266120000926-KRYS","pdf_url":null,"pub_time":1581609600000,"showTitleType":true,"size":0,"source":"sec_us","summary":"Statement of acquisition of beneficial ownership by individuals","symbol":"KRYS","title":"Statement of acquisition of beneficial ownership by individuals","titleType":"Beneficial Ownership Change","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1711279/000117266120000926/0001172661-20-000926-index.htm","us_notice_code":"Form SC 13G","us_title_en":"Statement of acquisition of beneficial ownership by individuals","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1055951/000117266120000926/orbimed-krys123119.htm","primary":true,"translateUrl":null,"linkName":"orbimed-krys123119.htm","type":"SC 13G","id":"NTFILEAbWTxuuUUSyhR9Kx","market":"us","size":86267}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Beneficial Ownership Change","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Beneficial Ownership Change","pubTime":"2020-02-14 00:00","pubTimestamp":1581609600,"title_zh":"Statement of acquisition of beneficial ownership by individuals","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"9098048","market":"us","labels":[],"media":"sec.gov","original_id":"AN119312520038241-KRYS","pdf_url":null,"pub_time":1581609600000,"showTitleType":true,"size":0,"source":"sec_us","summary":"[Amend] Statement of acquisition of beneficial ownership by individuals","symbol":"KRYS","title":"[Amend] Statement of acquisition of beneficial ownership by individuals","titleType":"Beneficial Ownership Change","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1711279/000119312520038241/0001193125-20-038241-index.htm","us_notice_code":"Form SC 13G/A","us_title_en":"[Amend] Statement of acquisition of beneficial ownership by individuals","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"SC 13G/A","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1298711/000119312520038241/d891710dsc13ga.htm","primary":true,"translateUrl":null,"linkName":"d891710dsc13ga.htm","type":"SC 13G/A","id":"NTFILE2fPRVeZHm7jDTMPY","market":"us","size":41484}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Beneficial Ownership Change","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Beneficial Ownership Change","pubTime":"2020-02-14 00:00","pubTimestamp":1581609600,"title_zh":"Amend] Statement of acquisition of beneficial ownership by individuals","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"9098011","market":"us","labels":[],"media":"sec.gov","original_id":"AN110465920021755-KRYS","pdf_url":null,"pub_time":1581609600000,"showTitleType":true,"size":0,"source":"sec_us","summary":"[Amend] Statement of acquisition of beneficial ownership by individuals","symbol":"KRYS","title":"[Amend] Statement of acquisition of beneficial ownership by individuals","titleType":"Beneficial Ownership Change","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1711279/000110465920021755/0001104659-20-021755-index.htm","us_notice_code":"Form SC 13G/A","us_title_en":"[Amend] Statement of acquisition of beneficial ownership by individuals","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"SCHEDULE 13G/A","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1263508/000110465920021755/tm205617-8_sc13ga.htm","primary":true,"translateUrl":null,"linkName":"tm205617-8_sc13ga.htm","type":"SC 13G/A","id":"NTFILE9M6apM68eBdL313X","market":"us","size":87326}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Beneficial Ownership Change","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Beneficial Ownership Change","pubTime":"2020-02-14 00:00","pubTimestamp":1581609600,"title_zh":"Amend] Statement of acquisition of beneficial ownership by individuals","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"9097568","market":"us","labels":[],"media":"sec.gov","original_id":"AN8025520001342-KRYS","pdf_url":null,"pub_time":1581609600000,"showTitleType":true,"size":0,"source":"sec_us","summary":"Statement of acquisition of beneficial ownership by individuals","symbol":"KRYS","title":"Statement of acquisition of beneficial ownership by individuals","titleType":"Beneficial Ownership Change","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1711279/000008025520001342/0000080255-20-001342-index.htm","us_notice_code":"Form SC 13G","us_title_en":"Statement of acquisition of beneficial ownership by individuals","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/80255/000008025520001342/krys13gdec19.txt","primary":true,"translateUrl":null,"linkName":"krys13gdec19.txt","type":"SC 13G","id":"NTFILEBQsQWmgguUqhApFt","market":"us","size":5239}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Beneficial Ownership Change","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Beneficial Ownership Change","pubTime":"2020-02-14 00:00","pubTimestamp":1581609600,"title_zh":"Statement of acquisition of beneficial ownership by individuals","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"9088158","market":"us","labels":[],"media":"sec.gov","original_id":"AN119312520033443-KRYS","pdf_url":null,"pub_time":1581523200000,"showTitleType":true,"size":0,"source":"sec_us","summary":"[Amend] Statement of acquisition of beneficial ownership by individuals","symbol":"KRYS","title":"[Amend] Statement of acquisition of beneficial ownership by individuals","titleType":"Beneficial Ownership Change","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1711279/000119312520033443/0001193125-20-033443-index.htm","us_notice_code":"Form SC 13G/A","us_title_en":"[Amend] Statement of acquisition of beneficial ownership by individuals","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"AMENDMENT NO. 2 TO SCHEDULE 13G","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1711279/000119312520033443/d888734dsc13ga.htm","primary":true,"translateUrl":null,"linkName":"d888734dsc13ga.htm","type":"SC 13G/A","id":"NTFILEEFn93yzVsPLNPjHY","market":"us","size":104915}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Beneficial Ownership Change","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Beneficial Ownership Change","pubTime":"2020-02-13 00:00","pubTimestamp":1581523200,"title_zh":"Amend] Statement of acquisition of beneficial ownership by individuals","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"9066199","market":"us","labels":[],"media":"sec.gov","original_id":"AN31506620001047-KRYS","pdf_url":null,"pub_time":1581004800000,"showTitleType":true,"size":0,"source":"sec_us","summary":"[Amend] Statement of acquisition of beneficial ownership by individuals","symbol":"KRYS","title":"[Amend] Statement of acquisition of beneficial ownership by individuals","titleType":"Beneficial Ownership Change","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1711279/000031506620001047/0000315066-20-001047-index.htm","us_notice_code":"Form SC 13G/A","us_title_en":"[Amend] Statement of acquisition of beneficial ownership by individuals","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/315066/000031506620001047/filing.txt","primary":true,"translateUrl":null,"linkName":"filing.txt","type":"SC 13G/A","id":"NTFILEAQL1HuT6QuRLrg56","market":"us","size":6702}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Beneficial Ownership Change","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Beneficial Ownership Change","pubTime":"2020-02-07 00:00","pubTimestamp":1581004800,"title_zh":"Amend] Statement of acquisition of beneficial ownership by individuals","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"8871209","market":"us","labels":[],"media":"sec.gov","original_id":"AN119312519283778-KRYS","pdf_url":null,"pub_time":1572883200000,"showTitleType":true,"size":0,"source":"sec_us","summary":"[Amend] Current report, items 2.02 and 9.01","symbol":"KRYS","title":"[Amend] Current report, items 2.02 and 9.01","titleType":"Major Issues Report","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1711279/000119312519283778/0001193125-19-283778-index.htm","us_notice_code":"Form 8-K/A","us_title_en":"[Amend] Current report, items 2.02 and 9.01","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"8-K/A","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1711279/000119312519283778/d825269d8ka.htm","primary":true,"translateUrl":null,"linkName":"d825269d8ka.htm","type":"8-K/A","id":"NTFILE7YQKoM125EiY7Bqi","market":"us","size":18687},{"description":"EX-99.1","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1711279/000119312519283778/d825269dex991.htm","primary":false,"translateUrl":null,"linkName":"d825269dex991.htm","type":"EX-99.1","id":"NTFILEAmeNDPKeaErVhBAy","market":"us","size":31043},{"description":"GRAPHIC","seq":3,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1711279/000119312519283778/g825269g1101045330481.jpg","primary":false,"translateUrl":null,"linkName":"g825269g1101045330481.jpg","type":"GRAPHIC","id":"NTFILEDZ5UBrxWxX7NtPp8","market":"us","size":4049},{"description":"GRAPHIC","seq":4,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1711279/000119312519283778/g825269g1102062429914.jpg","primary":false,"translateUrl":null,"linkName":"g825269g1102062429914.jpg","type":"GRAPHIC","id":"NTFILEBQTDL1DVLX1f8Bso","market":"us","size":2355}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Major Issues Report","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Major Issues Report","pubTime":"2019-11-05 00:00","pubTimestamp":1572883200,"title_zh":"Amend] Current report, items 2.02 and 9.01","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"8871213","market":"us","labels":[],"media":"sec.gov","original_id":"AN119312519282538-KRYS","pdf_url":null,"pub_time":1572796800000,"showTitleType":true,"size":0,"source":"sec_us","summary":"Current report, items 7.01 and 9.01","symbol":"KRYS","title":"Current report, items 7.01 and 9.01","titleType":"Major Issues Report","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1711279/000119312519282538/0001193125-19-282538-index.htm","us_notice_code":"Form 8-K","us_title_en":"Current report, items 7.01 and 9.01","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"EX-99.1","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1711279/000119312519282538/d793109dex991.htm","primary":true,"translateUrl":null,"linkName":"d793109dex991.htm","type":"EX-99.1","id":"NTFILEEFoMf7f11aewqQHA","market":"us","size":31043},{"description":"8-K","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1711279/000119312519282538/d793109d8k.htm","primary":false,"translateUrl":null,"linkName":"d793109d8k.htm","type":"8-K","id":"NTFILE3Jn3NpiB4nxJefCa","market":"us","size":17973},{"description":"GRAPHIC","seq":3,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1711279/000119312519282538/g793109g1101045330481.jpg","primary":false,"translateUrl":null,"linkName":"g793109g1101045330481.jpg","type":"GRAPHIC","id":"NTFILEDedUtfsNGWKMXvxB","market":"us","size":4049},{"description":"GRAPHIC","seq":4,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1711279/000119312519282538/g793109g1102062429914.jpg","primary":false,"translateUrl":null,"linkName":"g793109g1102062429914.jpg","type":"GRAPHIC","id":"NTFILE2tyPb1fczARpJyXQ","market":"us","size":2355}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Major Issues Report","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Major Issues Report","pubTime":"2019-11-04 00:00","pubTimestamp":1572796800,"title_zh":"Current report, items 7.01 and 9.01","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"8871212","market":"us","labels":[],"media":"sec.gov","original_id":"AN156459019039515-KRYS","pdf_url":null,"pub_time":1572796800000,"showTitleType":true,"size":0,"source":"sec_us","summary":"Quarterly report [Sections 13 or 15(d)]","symbol":"KRYS","title":"Quarterly report [Sections 13 or 15(d)]","titleType":"Quarterly Report","type":"usFinancials","url":"https://www.sec.gov/Archives/edgar/data/1711279/000156459019039515/0001564590-19-039515-index.htm","us_notice_code":"Form 10-Q","us_title_en":"Quarterly report [Sections 13 or 15(d)]","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"10-Q","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1711279/000156459019039515/krys-10q_20190930.htm","primary":true,"translateUrl":null,"linkName":"krys-10q_20190930.htm","type":"10-Q","id":"NTFILEEJcRJoGAK6LUU87N","market":"us","size":1358338},{"description":"EX-31.1","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1711279/000156459019039515/krys-ex311_7.htm","primary":false,"translateUrl":null,"linkName":"krys-ex311_7.htm","type":"EX-31.1","id":"NTFILEHKg4xAKEeFiyCZ5o","market":"us","size":16207},{"description":"EX-31.2","seq":3,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1711279/000156459019039515/krys-ex312_6.htm","primary":false,"translateUrl":null,"linkName":"krys-ex312_6.htm","type":"EX-31.2","id":"NTFILE7YoeVNj45jtRSahs","market":"us","size":16177},{"description":"EX-32.1","seq":4,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1711279/000156459019039515/krys-ex321_8.htm","primary":false,"translateUrl":null,"linkName":"krys-ex321_8.htm","type":"EX-32.1","id":"NTFILEHkdbR2xhbhCVX2BV","market":"us","size":18382},{"description":"XBRL INSTANCE DOCUMENT","seq":5,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1711279/000156459019039515/krys-20190930.xml","primary":false,"translateUrl":null,"linkName":"krys-20190930.xml","type":"EX-101.INS","id":"NTFILEBJW4nNGBkHRHEY64","market":"us","size":864159},{"description":"XBRL TAXONOMY EXTENSION SCHEMA","seq":6,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1711279/000156459019039515/krys-20190930.xsd","primary":false,"translateUrl":null,"linkName":"krys-20190930.xsd","type":"EX-101.SCH","id":"NTFILE5iXSuHTVZj2HzcUG","market":"us","size":31717},{"description":"XBRL TAXONOMY EXTENSION CALCULATION LINKBASE","seq":7,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1711279/000156459019039515/krys-20190930_cal.xml","primary":false,"translateUrl":null,"linkName":"krys-20190930_cal.xml","type":"EX-101.CAL","id":"NTFILECcvZb1N4Ni1tjDty","market":"us","size":35787},{"description":"XBRL TAXONOMY EXTENSION DEFINITION LINKBASE","seq":8,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1711279/000156459019039515/krys-20190930_def.xml","primary":false,"translateUrl":null,"linkName":"krys-20190930_def.xml","type":"EX-101.DEF","id":"NTFILE55cSbASXA6hsr61N","market":"us","size":94613},{"description":"XBRL TAXONOMY EXTENSION LABEL LINKBASE","seq":9,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1711279/000156459019039515/krys-20190930_lab.xml","primary":false,"translateUrl":null,"linkName":"krys-20190930_lab.xml","type":"EX-101.LAB","id":"NTFILE8894TWPbe8XaBpT3","market":"us","size":271724},{"description":"XBRL TAXONOMY EXTENSION PRESENTATION LINKBASE","seq":10,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1711279/000156459019039515/krys-20190930_pre.xml","primary":false,"translateUrl":null,"linkName":"krys-20190930_pre.xml","type":"EX-101.PRE","id":"NTFILEHMjPax1fyqejKN8f","market":"us","size":210154}],"type_name":"Financial Report","type_name_en":"Financial Report","titleTypeEn":"Quarterly Report","us_type":"财务报告","us_type_zh":"财务报告","earn_infos":[],"event_type":"important_notice","event_name":"Quarterly Report","pubTime":"2019-11-04 00:00","pubTimestamp":1572796800,"title_zh":"Quarterly report [Sections 13 or 15(d","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"8871208","market":"us","labels":[],"media":"sec.gov","original_id":"AN119312519276931-KRYS","pdf_url":null,"pub_time":1572278400000,"showTitleType":true,"size":0,"source":"sec_us","summary":"Current report, items 7.01 and 9.01","symbol":"KRYS","title":"Current report, items 7.01 and 9.01","titleType":"Major Issues Report","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1711279/000119312519276931/0001193125-19-276931-index.htm","us_notice_code":"Form 8-K","us_title_en":"Current report, items 7.01 and 9.01","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"EX-99.1","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1711279/000119312519276931/d825146dex991.htm","primary":true,"translateUrl":null,"linkName":"d825146dex991.htm","type":"EX-99.1","id":"NTFILEEKf1FQrF2bqMkVFK","market":"us","size":27578},{"description":"8-K","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1711279/000119312519276931/d825146d8k.htm","primary":false,"translateUrl":null,"linkName":"d825146d8k.htm","type":"8-K","id":"NTFILED5cVkAycTTLdYgyh","market":"us","size":17695},{"description":"GRAPHIC","seq":3,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1711279/000119312519276931/g825146g1028164336081.jpg","primary":false,"translateUrl":null,"linkName":"g825146g1028164336081.jpg","type":"GRAPHIC","id":"NTFILEDfHjr9p37s4DH5ZL","market":"us","size":2930}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Major Issues Report","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Major Issues Report","pubTime":"2019-10-29 00:00","pubTimestamp":1572278400,"title_zh":"Current report, items 7.01 and 9.01","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"8449919","market":"us","labels":[],"media":"sec.gov","original_id":"AN119312519212735-KRYS","pdf_url":null,"pub_time":1564934400000,"showTitleType":true,"size":0,"source":"sec_us","summary":"Current report, items 2.02 and 9.01","symbol":"KRYS","title":"Current report, items 2.02 and 9.01","titleType":"Major Issues Report","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1711279/000119312519212735/0001193125-19-212735-index.htm","us_notice_code":"Form 8-K","us_title_en":"Current report, items 2.02 and 9.01","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"8-K","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1711279/000119312519212735/d97507d8k.htm","primary":true,"translateUrl":null,"linkName":"d97507d8k.htm","type":"8-K","id":"NTFILE8CpRQ2ZSdGYLouvk","market":"us","size":17885},{"description":"EX-99.1","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1711279/000119312519212735/d97507dex991.htm","primary":false,"translateUrl":null,"linkName":"d97507dex991.htm","type":"EX-99.1","id":"NTFILE9dL538ESSJe4SWKe","market":"us","size":27318},{"description":"GRAPHIC","seq":3,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1711279/000119312519212735/g97507g0805184826300.jpg","primary":false,"translateUrl":null,"linkName":"g97507g0805184826300.jpg","type":"GRAPHIC","id":"NTFILEAiF5z6tEUp7rxS3r","market":"us","size":2355},{"description":"GRAPHIC","seq":4,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1711279/000119312519212735/g97507g0805184826488.jpg","primary":false,"translateUrl":null,"linkName":"g97507g0805184826488.jpg","type":"GRAPHIC","id":"NTFILE61qExiuXu3bvQaUt","market":"us","size":4350}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Major Issues Report","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Major Issues Report","pubTime":"2019-08-05 00:00","pubTimestamp":1564934400,"title_zh":"Current report, items 2.02 and 9.01","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"8449641","market":"us","labels":[],"media":"sec.gov","original_id":"AN156459019028548-KRYS","pdf_url":null,"pub_time":1564934400000,"showTitleType":true,"size":0,"source":"sec_us","summary":"Quarterly report [Sections 13 or 15(d)]","symbol":"KRYS","title":"Quarterly report [Sections 13 or 15(d)]","titleType":"Quarterly Report","type":"usFinancials","url":"https://www.sec.gov/Archives/edgar/data/1711279/000156459019028548/0001564590-19-028548-index.htm","us_notice_code":"Form 10-Q","us_title_en":"Quarterly report [Sections 13 or 15(d)]","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"10-Q","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1711279/000156459019028548/krys-10q_20190630.htm","primary":true,"translateUrl":null,"linkName":"krys-10q_20190630.htm","type":"10-Q","id":"NTFILEEBG5Vsf4tzjGaift","market":"us","size":1305600},{"description":"EX-31.1","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1711279/000156459019028548/krys-ex311_6.htm","primary":false,"translateUrl":null,"linkName":"krys-ex311_6.htm","type":"EX-31.1","id":"NTFILE8fekCL4VB5tqqYrx","market":"us","size":23529},{"description":"EX-31.2","seq":3,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1711279/000156459019028548/krys-ex312_7.htm","primary":false,"translateUrl":null,"linkName":"krys-ex312_7.htm","type":"EX-31.2","id":"NTFILE6KCgUS379bgXvUsa","market":"us","size":23155},{"description":"EX-32.1","seq":4,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1711279/000156459019028548/krys-ex321_8.htm","primary":false,"translateUrl":null,"linkName":"krys-ex321_8.htm","type":"EX-32.1","id":"NTFILEFApayR6MSn8vaxqd","market":"us","size":18253},{"description":"XBRL INSTANCE DOCUMENT","seq":5,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1711279/000156459019028548/krys-20190630.xml","primary":false,"translateUrl":null,"linkName":"krys-20190630.xml","type":"EX-101.INS","id":"NTFILE5eeuUQMqvYUoBnrh","market":"us","size":903740},{"description":"XBRL TAXONOMY EXTENSION SCHEMA","seq":6,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1711279/000156459019028548/krys-20190630.xsd","primary":false,"translateUrl":null,"linkName":"krys-20190630.xsd","type":"EX-101.SCH","id":"NTFILEB4qCXYZfh26UgLva","market":"us","size":31485},{"description":"XBRL TAXONOMY EXTENSION CALCULATION LINKBASE","seq":7,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1711279/000156459019028548/krys-20190630_cal.xml","primary":false,"translateUrl":null,"linkName":"krys-20190630_cal.xml","type":"EX-101.CAL","id":"NTFILE4siDSx6vk1EzS5Yi","market":"us","size":35759},{"description":"XBRL TAXONOMY EXTENSION DEFINITION LINKBASE","seq":8,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1711279/000156459019028548/krys-20190630_def.xml","primary":false,"translateUrl":null,"linkName":"krys-20190630_def.xml","type":"EX-101.DEF","id":"NTFILEHLPfJHZyuqae6GpU","market":"us","size":97422},{"description":"XBRL TAXONOMY EXTENSION LABEL LINKBASE","seq":9,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1711279/000156459019028548/krys-20190630_lab.xml","primary":false,"translateUrl":null,"linkName":"krys-20190630_lab.xml","type":"EX-101.LAB","id":"NTFILEE9u8vFzRHaQuvoT2","market":"us","size":271990},{"description":"XBRL TAXONOMY EXTENSION PRESENTATION LINKBASE","seq":10,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1711279/000156459019028548/krys-20190630_pre.xml","primary":false,"translateUrl":null,"linkName":"krys-20190630_pre.xml","type":"EX-101.PRE","id":"NTFILEDvCvT3k2RS2dXGmj","market":"us","size":211690}],"type_name":"Financial Report","type_name_en":"Financial Report","titleTypeEn":"Quarterly Report","us_type":"财务报告","us_type_zh":"财务报告","earn_infos":[],"event_type":"important_notice","event_name":"Quarterly Report","pubTime":"2019-08-05 00:00","pubTimestamp":1564934400,"title_zh":"Quarterly report [Sections 13 or 15(d","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"8335866","market":"us","labels":[],"media":"sec.gov","original_id":"AN119312519184347-KRYS","pdf_url":null,"pub_time":1561564800000,"showTitleType":true,"size":0,"source":"sec_us","summary":"Current report, items 1.01 and 9.01","symbol":"KRYS","title":"Current report, items 1.01 and 9.01","titleType":"Major Issues Report","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1711279/000119312519184347/0001193125-19-184347-index.htm","us_notice_code":"Form 8-K","us_title_en":"Current report, items 1.01 and 9.01","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"8-K","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1711279/000119312519184347/d494443d8k.htm","primary":true,"translateUrl":null,"linkName":"d494443d8k.htm","type":"8-K","id":"NTFILE3jnKmkWFyemgfiPd","market":"us","size":20916},{"description":"EX-1.1","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1711279/000119312519184347/d494443dex11.htm","primary":false,"translateUrl":null,"linkName":"d494443dex11.htm","type":"EX-1.1","id":"NTFILE99uc4vySaTHZRJvR","market":"us","size":152019},{"description":"EX-5.1","seq":3,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1711279/000119312519184347/d494443dex51.htm","primary":false,"translateUrl":null,"linkName":"d494443dex51.htm","type":"EX-5.1","id":"NTFILE7su5qsft1vshrgUn","market":"us","size":8120},{"description":"GRAPHIC","seq":4,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1711279/000119312519184347/g494443g0627085001774.jpg","primary":false,"translateUrl":null,"linkName":"g494443g0627085001774.jpg","type":"GRAPHIC","id":"NTFILErzqpP4AsKF7wzs23","market":"us","size":2531}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Major Issues Report","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Major Issues Report","pubTime":"2019-06-27 00:00","pubTimestamp":1561564800,"title_zh":"Current report, items 1.01 and 9.01","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"8322932","market":"us","labels":[],"media":"sec.gov","original_id":"AN119312519179370-KRYS","pdf_url":null,"pub_time":1561305600000,"showTitleType":true,"size":0,"source":"sec_us","summary":"Current report, items 7.01 and 9.01","symbol":"KRYS","title":"Current report, items 7.01 and 9.01","titleType":"Major Issues Report","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1711279/000119312519179370/0001193125-19-179370-index.htm","us_notice_code":"Form 8-K","us_title_en":"Current report, items 7.01 and 9.01","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"8-K","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1711279/000119312519179370/d744907d8k.htm","primary":true,"translateUrl":null,"linkName":"d744907d8k.htm","type":"8-K","id":"NTFILEAZg4TkqbegjM832T","market":"us","size":18391},{"description":"EX-99.1","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1711279/000119312519179370/d744907dex991.htm","primary":false,"translateUrl":null,"linkName":"d744907dex991.htm","type":"EX-99.1","id":"NTFILE5mtosuwopUitUdyo","market":"us","size":31575},{"description":"GRAPHIC","seq":3,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1711279/000119312519179370/g744907g0624071651339.jpg","primary":false,"translateUrl":null,"linkName":"g744907g0624071651339.jpg","type":"GRAPHIC","id":"NTFILE5p3mzhZDUV1bMyGJ","market":"us","size":2930}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Major Issues Report","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Major Issues Report","pubTime":"2019-06-24 00:00","pubTimestamp":1561305600,"title_zh":"Current report, items 7.01 and 9.01","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"8304976","market":"us","labels":[],"media":"sec.gov","original_id":"AN120919119037449-KRYS","pdf_url":null,"pub_time":1560700800000,"showTitleType":true,"size":0,"source":"sec_us","summary":"Statement of changes in beneficial ownership of securities","symbol":"KRYS","title":"Statement of changes in beneficial ownership of securities","titleType":"Statement Of Changes In Beneficial Ownership","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1711279/000120919119037449/0001209191-19-037449-index.htm","us_notice_code":"Form 4","us_title_en":"Statement of changes in beneficial ownership of securities","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"FORM 4 SUBMISSION","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1339375/000120919119037449/xslF345X03/doc4.xml","primary":true,"translateUrl":null,"linkName":"doc4.html","type":"4","id":"NTFILEEVNrPErakPddWdqX","market":"us","size":0},{"description":"FORM 4 SUBMISSION","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1339375/000120919119037449/doc4.xml","primary":false,"translateUrl":null,"linkName":"doc4.xml","type":"4","id":"NTFILECRqc9qWbxznhJbQX","market":"us","size":3889}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Statement Of Changes In Beneficial Ownership","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Statement Of Changes In Beneficial Ownership","pubTime":"2019-06-17 00:00","pubTimestamp":1560700800,"title_zh":"Statement of changes in beneficial ownership of securities","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"8248595","market":"us","labels":[],"media":"sec.gov","original_id":"AN119312519161198-KRYS","pdf_url":null,"pub_time":1559145600000,"showTitleType":true,"size":0,"source":"sec_us","summary":"Current report, item 5.07","symbol":"KRYS","title":"Current report, item 5.07","titleType":"Major Issues Report","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1711279/000119312519161198/0001193125-19-161198-index.htm","us_notice_code":"Form 8-K","us_title_en":"Statement of changes in beneficial ownership of securities","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"FORM 8-K","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1711279/000119312519161198/d755476d8k.htm","primary":true,"translateUrl":null,"linkName":"d755476d8k.htm","type":"8-K","id":"NTFILEDkd5axRu9gPzEpGv","market":"us","size":20292}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Major Issues Report","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Major Issues Report","pubTime":"2019-05-30 00:00","pubTimestamp":1559145600,"title_zh":"Current report, item 5.07","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"8178725","market":"us","labels":[],"media":"sec.gov","original_id":"AN119312519144386-KRYS","pdf_url":null,"pub_time":1557417600000,"showTitleType":true,"size":0,"source":"sec_us","summary":"Current report, items 2.02 and 9.01","symbol":"KRYS","title":"Current report, items 2.02 and 9.01","titleType":"Major Issues Report","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1711279/000119312519144386/0001193125-19-144386-index.htm","us_notice_code":"Form 8-K","us_title_en":"Statement of changes in beneficial ownership of securities","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"8-K","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1711279/000119312519144386/d747952d8k.htm","primary":true,"translateUrl":null,"linkName":"d747952d8k.htm","type":"8-K","id":"NTFILECbTHGcm4FXEbzfjs","market":"us","size":18446},{"description":"EX-99.1","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1711279/000119312519144386/d747952dex991.htm","primary":false,"translateUrl":null,"linkName":"d747952dex991.htm","type":"EX-99.1","id":"NTFILECf6fEbw9A7Zvqv8D","market":"us","size":18838},{"description":"GRAPHIC","seq":3,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1711279/000119312519144386/g747952g0511005609392.jpg","primary":false,"translateUrl":null,"linkName":"g747952g0511005609392.jpg","type":"GRAPHIC","id":"NTFILE81SGpC82Nd8MTvUK","market":"us","size":4006},{"description":"GRAPHIC","seq":4,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1711279/000119312519144386/g747952g0511005609548.jpg","primary":false,"translateUrl":null,"linkName":"g747952g0511005609548.jpg","type":"GRAPHIC","id":"NTFILE5niXFcKX4qbKgRdV","market":"us","size":2355}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Major Issues Report","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Major Issues Report","pubTime":"2019-05-10 00:00","pubTimestamp":1557417600,"title_zh":"Current report, items 2.02 and 9.01","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"8158502","market":"us","labels":[],"media":"sec.gov","original_id":"AN156459019016236-KRYS","pdf_url":null,"pub_time":1557158400000,"showTitleType":true,"size":0,"source":"sec_us","summary":"Quarterly report [Sections 13 or 15(d)]","symbol":"KRYS","title":"Quarterly report [Sections 13 or 15(d)]","titleType":"Quarterly Report","type":"usFinancials","url":"https://www.sec.gov/Archives/edgar/data/1711279/000156459019016236/0001564590-19-016236-index.htm","us_notice_code":"Form 10-Q","us_title_en":"Current report, item 5.07","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"10-Q","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1711279/000156459019016236/krys-10q_20190331.htm","primary":true,"translateUrl":null,"linkName":"krys-10q_20190331.htm","type":"10-Q","id":"NTFILEFC6Z5YVD7appy63b","market":"us","size":1044793},{"description":"EX-31.1","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1711279/000156459019016236/krys-ex311_8.htm","primary":false,"translateUrl":null,"linkName":"krys-ex311_8.htm","type":"EX-31.1","id":"NTFILE86w9jPDWyoA25nkV","market":"us","size":23526},{"description":"EX-31.2","seq":3,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1711279/000156459019016236/krys-ex312_7.htm","primary":false,"translateUrl":null,"linkName":"krys-ex312_7.htm","type":"EX-31.2","id":"NTFILE2vWf8LGEpsfYpD4j","market":"us","size":24127},{"description":"EX-32.1","seq":4,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1711279/000156459019016236/krys-ex321_6.htm","primary":false,"translateUrl":null,"linkName":"krys-ex321_6.htm","type":"EX-32.1","id":"NTFILEBYwaQzT8rBKwxKb4","market":"us","size":24066}],"type_name":"Financial Report","type_name_en":"Financial Report","titleTypeEn":"Quarterly Report","us_type":"财务报告","us_type_zh":"财务报告","earn_infos":[],"event_type":"important_notice","event_name":"Quarterly Report","pubTime":"2019-05-07 00:00","pubTimestamp":1557158400,"title_zh":"Quarterly report [Sections 13 or 15(d","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"7293200","market":"us","labels":[],"media":"sec.gov","original_id":"AN119312518296135-KRYS","pdf_url":null,"pub_time":1539014400000,"showTitleType":true,"size":0,"source":"sec_us","summary":"","symbol":"KRYS","title":"","titleType":"Correspondence","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1711279/000119312518296135/0001193125-18-296135-index.htm","us_notice_code":"Form CORRESP","us_title_en":"[Cover]Correspondence","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1711279/000119312518296135/filename1.htm","primary":true,"translateUrl":null,"linkName":"filename1.htm","type":"CORRESP","id":"NTFILEEtAtzoQ7PEpdFb3r","market":"us","size":5106}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Correspondence","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Correspondence","pubTime":"2018-10-09 00:00","pubTimestamp":1539014400,"title_zh":"","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"6915110","market":"us","labels":[],"media":"sec.gov","original_id":"AN119312517286276-KRYS","pdf_url":null,"pub_time":1505404800000,"showTitleType":true,"size":0,"source":"sec_us","summary":"","symbol":"KRYS","title":"","titleType":"Correspondence","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1711279/000119312517286276/0001193125-17-286276-index.htm","us_notice_code":"Form CORRESP","us_title_en":"[Cover]Correspondence","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1711279/000119312517286276/filename1.htm","primary":true,"translateUrl":null,"linkName":"filename1.htm","type":"CORRESP","id":"NTFILE9SW5MeKznSdKQKv5","market":"us","size":4363}],"type_name":"Transaction Related","type_name_en":"Transaction Related","titleTypeEn":"Correspondence","us_type":"交易披露","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"Correspondence","pubTime":"2017-09-15 00:00","pubTimestamp":1505404800,"title_zh":"","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0}],"pageSize":20,"totalPage":12,"pageCount":11,"totalSize":226,"code":"91000000","status":"200"}]}}