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Bicycle Therapeutics Limited

4.33

-0.0400-0.92%

Volume:34.70K

Turnover:149.71K

Market Cap:302.28M

PE:-1.58

High:4.34

Open:4.33

Low:4.28

Close:4.37

52wk High:9.16

52wk Low:3.75

Shares:69.81M

Float Shares:3.08M

Volume Ratio:0.59

T/O Rate:1.13%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-2.7382

EPS(LYR):-3.1605

ROE:-32.30%

ROA:-17.91%

PB:0.59

PE(LYR):-1.37

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Overview Company News Filings

Bicycle Therapeutics posts corporate presentation outlining Bicycle molecule platform and oncology pipeline

European Equities Traded in the US as American Depositary Receipts Edge Higher in Friday Trading

MT Newswires Live

Bicycle Therapeutics reports initial Duravelo-2 Phase 2 data in metastatic urothelial cancer

Morgan Stanley Sticks to Its Hold Rating for Bicycle Therapeutics (BCYC)

European Equities Traded in the US as American Depositary Receipts Flat in Friday Trading; Gain 1.3% for Week

MT Newswires Live

Bicycle Therapeutics PLC reports results for the quarter ended March 31 - Earnings Summary

Analysts Offer Insights on Healthcare Companies: Bicycle Therapeutics (BCYC) and Option Care Health (OPCH)

European Equities Traded in the US as American Depositary Receipts Rise in Thursday Trading

MT Newswires Live

Bicycle Therapeutics Q1 FY26 net loss holds at USD 60.8 million; revenue drops to USD 0.9 million

Bicycle Therapeutics Q1 Pretax Profit USD -60.653 Million

THOMSON REUTERS

Bicycle Therapeutics Q1 Operating Expenses USD 66.369 Million

THOMSON REUTERS

Calendar of U.S. Earnings Expected in the Week Ahead

Bicycle Therapeutics PLC expected to post a loss of 62 cents a share - Earnings Preview

Bicycle Therapeutics presents interim Duravelo-2 BT8009 plus Keytruda data at ASCO 2026

Bicycle Therapeutics publishes investor presentation on Bicycle molecule platform and oncology pipeline

Bicycle Therapeutics doses first patient in Phase 2 pancreatic cancer trial for nuzefatide pevedotin

European Equities Traded in the US as ADRs Rise in Tuesday Trading

MT Newswires Live

European Equities Traded in the US as American Depositary Receipts Start Week on Flat Note in Monday Trading

MT Newswires Live

Bicycle Therapeutics Is Maintained at Equal-Weight by Morgan Stanley

Bicycle Therapeutics COO Jennifer Scott Perry disposes of shares worth $6,803

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Therapeutics posts corporate presentation outlining Bicycle molecule platform and oncology pipeline","url":"https://stock-news.laohu8.com/highlight/detail?id=2640564957","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2640564957?lang=en_us&edition=fundamental","pubTime":"2026-06-01 21:56","pubTimestamp":1780322172,"startTime":"0","endTime":"0","summary":"Bicycle Therapeutics outlined an oncology-focused pipeline built on its Bicycle molecule platform, aiming to deliver payloads to hard-to-drug targets.Lead program nuzefatide pevedotin, an EphA2-targeting Bicycle drug conjugate, is in a Phase 2 open-label trial in second-line or later pancreatic cancer.Presentation highlighted safety data in 161 exposed patients, citing no hemorrhage events to date and no Grade 3 peripheral neuropathy reported.Cash and cash equivalents totaled USD 559.5 million as of March 31, 2026, with expected financial runway into 2030.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Bicycle Therapeutics plc published the original content used to generate this news brief on June 01, 2026, and is solely responsible fo","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260601:nNDL289kMR:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BCYC","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2637080348","title":"European Equities Traded in the US as American Depositary Receipts Edge Higher in Friday Trading","url":"https://stock-news.laohu8.com/highlight/detail?id=2637080348","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2637080348?lang=en_us&edition=fundamental","pubTime":"2026-05-22 23:06","pubTimestamp":1779462387,"startTime":"0","endTime":"0","summary":"European equities traded in the US as American depositary receipts were trending slightly higher late Friday morning, edging up 0.11% to 1,880.31 on the S&P Europe Select ADR Index, which has surged 3","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["BDRX","BK4505","NTZ","BK4554","IE00BMPRXR70.SGD","LNOK","TRIB","AUTL","SLN","BK4007","BK7142","BK4139","BBVA","BK4201","IE00BMPRXN33.USD","SAN","BCYC","EPV","GRFS","MREO","E","SQNS","BK4207","BK4117","BK4521","AFG","SAN.AU","BK4020","BK4591","NOK","BK4082","AKTX","ERIC","BK4547","BK4107","BK4141","BK4515","BK4095","PUK","IEUR","BK4162"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2637352795","title":"Bicycle Therapeutics reports initial Duravelo-2 Phase 2 data in metastatic urothelial cancer","url":"https://stock-news.laohu8.com/highlight/detail?id=2637352795","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2637352795?lang=en_us&edition=fundamental","pubTime":"2026-05-22 05:00","pubTimestamp":1779397235,"startTime":"0","endTime":"0","summary":"Bicycle Therapeutics flagged initial data from its randomized Phase 2 Duravelo-2 trial of Nectin-4 drug conjugate zelenectide pevedotin in metastatic urothelial cancer, with results set for presentation at the 2026 ASCO Annual Meeting.The dose-optimized regimen in combination with Merck’s Keytruda produced responses broadly in line with published first-line standards of care, supporting continued development in an increasingly competitive setting.The company highlighted a potentially differentiated tolerability profile versus published standard-of-care benchmarks, with fewer treatment-limiting side effects such as skin toxicity and peripheral neuropathy.Updated Phase 1 Duravelo-1 findings will also be presented at ASCO, pointing to clinically meaningful disease control and progression outcomes in cisplatin-ineligible patients treated with the combination.Additional results from the randomized Phase 2 program are expected in 2H 2026, a key catalyst for next-step partnering and registrat","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260521:nNDL9Z7jVB:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BCYC","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2636349076","title":"Morgan Stanley Sticks to Its Hold Rating for Bicycle Therapeutics (BCYC)","url":"https://stock-news.laohu8.com/highlight/detail?id=2636349076","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2636349076?lang=en_us&edition=fundamental","pubTime":"2026-05-18 20:59","pubTimestamp":1779109181,"startTime":"0","endTime":"0","summary":"Morgan Stanley analyst Maxwell Skor maintained a Hold rating on Bicycle Therapeutics today and set a price target of $4.45. Skor covers the Healthc...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/morgan-stanley-sticks-to-its-hold-rating-for-bicycle-therapeutics-bcyc-blurbs-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/morgan-stanley-sticks-to-its-hold-rating-for-bicycle-therapeutics-bcyc-blurbs-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BCYC"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2632643568","title":"European Equities Traded in the US as American Depositary Receipts Flat in Friday Trading; Gain 1.3% for Week","url":"https://stock-news.laohu8.com/highlight/detail?id=2632643568","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2632643568?lang=en_us&edition=fundamental","pubTime":"2026-05-01 23:10","pubTimestamp":1777648259,"startTime":"0","endTime":"0","summary":"European equities traded in the US as American depositary receipts were trending marginally higher late Friday morning, rising 0.05% to 1,824.45 on the S&P Europe Select ADR Index, which is up 1.25% f","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["SHEH","IE00BMPRXN33.USD","LU1093756168.USD","SHEL","DIG","NTZ","LU1829250122.USD","GUSH","LU0124676726.USD","UL","DRIP","BDRX","BK4107","UN","PSO","BK4535","USE","BK4547","BPH","LU0162691827.USD","AKTX","LNOK","NVOX","ERX","IE00BKVL7J92.USD","LU0098860793.USD","IE00BZ1G4Q59.USD","LU0689626769.HKD","IXC","BNTX","LU0154236417.USD","PXJ","LU0006061336.USD","CLLS","LU0300736492.USD","LU1093756325.SGD","CUK","DBVT","LU2236285917.USD","DRLL","BK4111","IEO","BK4568","BK4139","NOK","BK4204","ULVR.UK","BK4532","BK7104","LU1162221912.USD","BK4585","BK4588","BK4117","BK4095","NVOH","LU0300736062.USD","DBC","BK4201","LU0278409577.USD","BK4007","AMRN","LU0320765646.SGD","VDE","BK4599","BCYC","NVO","BK4020","DBE","BK4548","BK4142","EQNR","BK4592","IE00BMPRXR70.SGD","BK4183","BP","BK4551","LU0072461881.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2632191886","title":"Bicycle Therapeutics PLC reports results for the quarter ended March 31 - Earnings Summary","url":"https://stock-news.laohu8.com/highlight/detail?id=2632191886","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2632191886?lang=en_us&edition=fundamental","pubTime":"2026-05-01 19:07","pubTimestamp":1777633623,"startTime":"0","endTime":"0","summary":"Bicycle Therapeutics PLC reports results for the quarter ended March 31 - Earnings SummaryBicycle Therapeutics PLC BCYC.OQ reported a quarterly adjusted loss of 87 cents per share for the quarter ende","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260501:nL8N41E0LD:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","BCYC"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2632650170","title":"Analysts Offer Insights on Healthcare Companies: Bicycle Therapeutics (BCYC) and Option Care Health (OPCH)","url":"https://stock-news.laohu8.com/highlight/detail?id=2632650170","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2632650170?lang=en_us&edition=fundamental","pubTime":"2026-05-01 02:20","pubTimestamp":1777573209,"startTime":"0","endTime":"0","summary":"There’s a lot to be optimistic about in the Healthcare sector as 2 analysts just weighed in on Bicycle Therapeutics (BCYC) and Option Care Health (...","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/analysts-offer-insights-on-healthcare-companies-bicycle-therapeutics-bcyc-and-option-care-health-opch-blurbs-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/analysts-offer-insights-on-healthcare-companies-bicycle-therapeutics-bcyc-and-option-care-health-opch-blurbs-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["OPCH","BK4581","HCSG","LU0012050646.USD","BK4196","LU0029874061.USD","LU0128526141.USD","BK4139","BK4588","XLV","BK4585","LU2065731478.USD","XBI","LU0106261612.USD","BCYC","LABU","BK4137"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2632652327","title":"European Equities Traded in the US as American Depositary Receipts Rise in Thursday Trading","url":"https://stock-news.laohu8.com/highlight/detail?id=2632652327","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2632652327?lang=en_us&edition=fundamental","pubTime":"2026-04-30 23:06","pubTimestamp":1777561599,"startTime":"0","endTime":"0","summary":"European equities traded in the US as American depositary receipts rose late Thursday morning, gaining 2.20% to 1,818.51 on the S&P Europe Select ADR Index.From continental Europe, the gainers were led by pharmaceutical company Novo Nordisk  and lender ING Groep , which advanced 5.3% and 4.9% respectively. They were followed by biopharmaceutical firm Grifols  and consumer goods firm Unilever , which rose 3.2% and 3.1% respectively.The decliners from continental Europe were led by internet advertising firm Criteo  and telecommunications company Nokia , which fell 3.2% and 1.9% respectively.The gainers from the UK were led by cruise line operator Carnival  and utilities company National Grid , which rose 4.8% and 3.5% respectively. They were followed by Lloyds Banking Group  and telecommunications operator Vodafone Group , which were up 2.6% and 2.3% respectively.The decliners from the UK and Ireland were led by software firm Endava  and Bicycle Therapeutics , which lost 5.2% and 2.3% re","market":"sh","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["BK4585","BK4132","BK4134","BK4208","BK4547","BK4532","LU0648005311.SGD","IE00BMPRXR70.SGD","CUK","BK4117","BK4142","BK4020","LU0154236417.USD","LU0689626769.HKD","NVOX","UN","BK4505","BK4521","BK4592","NGG","LNOK","NVO","GRFS","LU0124676726.USD","ULVR.UK","BK7505","LU0084288595.USD","IE00BKVL7J92.USD","LU1093756168.USD","BCYC","CRTO","BK4107","VOD","MREO","BK4588","BK4183","LU1093756325.SGD","DAVA","NOK","NVOH","UL","BK4207","IE00BMPRXN33.USD","ING","BK7141","BK7104","IE00BFMHRM44.USD","IE00BZ1G4Q59.USD","BK4007","BK4139","AMRN","LYG","BK4599","BK4009"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2631563559","title":"Bicycle Therapeutics Q1 FY26 net loss holds at USD 60.8 million; revenue drops to USD 0.9 million","url":"https://stock-news.laohu8.com/highlight/detail?id=2631563559","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2631563559?lang=en_us&edition=fundamental","pubTime":"2026-04-30 19:01","pubTimestamp":1777546877,"startTime":"0","endTime":"0","summary":"Bicycle Therapeutics posted a Q1 net loss of 60.8 million, or $ per share.Operating loss narrowed to 65.5 million on lower R&D and G&A costs.Cash and cash equivalents declined to 559.5 million as of March 31, 2026.Pipeline update highlighted first patient dosed in Phase 2 PDAC trial of nuzefatide pevedotin; preferred dose set at 8 mg/m2 Q2W.Strategic reprioritization included converting Duravelo-2 into a randomized Phase 2 trial, shutting enrollment for Duravelo-3 and Duravelo-4, and cutting workforce about 30%.Management said actions should cut annual operating expenses about 50% and extend cash runway into 2030.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Bicycle Therapeutics plc published the original content used to generate thi","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260430:nNDL9cKpXk:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BCYC","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2631330646","title":"Bicycle Therapeutics Q1 Pretax Profit USD -60.653 Million","url":"https://stock-news.laohu8.com/highlight/detail?id=2631330646","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2631330646?lang=en_us&edition=fundamental","pubTime":"2026-04-30 19:00","pubTimestamp":1777546801,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260430:nPLXD4F1A3:3","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BCYC","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2631041633","title":"Bicycle Therapeutics Q1 Operating Expenses USD 66.369 Million","url":"https://stock-news.laohu8.com/highlight/detail?id=2631041633","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2631041633?lang=en_us&edition=fundamental","pubTime":"2026-04-30 19:00","pubTimestamp":1777546801,"startTime":"0","endTime":"0","summary":null,"market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260430:nPLXD4F1A3:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BCYC","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2631682969","title":"Calendar of U.S. Earnings Expected in the Week Ahead","url":"https://stock-news.laohu8.com/highlight/detail?id=2631682969","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2631682969?lang=en_us&edition=fundamental","pubTime":"2026-04-30 18:00","pubTimestamp":1777543200,"startTime":"0","endTime":"0","summary":"Major companies tentatively scheduled to report quarterly earnings in the week ahead, with earnings estimates provided by FactSet Research Systems Inc.·A. O. Smith Corp                                 1Q       .94    6:55 AM. ·Air Prod & Chem                                  2Q      3.06    6:00 AM. ·Altria Grp Inc                                    1Q      1.25    7:00 AM. ·APi Grp Corp                                     1Q       .30    7:30 AM","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["AUTL","AX","ADT","ALDX","ALEC","AXTI","BDC","ACA","BIO","ARVN","AVTX","BAX","ALHC","AXTA","AIN","BAND","AEM","ACCO","ARDX","AME","BBVA","BCYC","BMY","BSAC","ALNY","CAH","APG","BIO.B","AIG","CABO","BBIO","APLS","ANGX","BOOM","ATR","BFLY","AES","BLDR","ASUR","BC","AAPL","AMGN","BR","ASND","AOS","AUPH","ATI","AJG","APD","BZH"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2630739756","title":"Bicycle Therapeutics PLC  expected to post a loss of 62 cents a share - Earnings Preview","url":"https://stock-news.laohu8.com/highlight/detail?id=2630739756","media":"Reuters","labels":["dataReport","preview"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2630739756?lang=en_us&edition=fundamental","pubTime":"2026-04-27 21:50","pubTimestamp":1777297806,"startTime":"0","endTime":"0","summary":"Bicycle Therapeutics PLC  expected to post a loss of62cents a share - Earnings Preview Bicycle Therapeutics PLC BCYC.OQ BCYC.O is expected to  show a fall in quarterly revenue when it reports  results","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260427:nL8N41A1IN:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"dataReport,preview","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","BCYC"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2629302080","title":"Bicycle Therapeutics presents interim Duravelo-2 BT8009 plus Keytruda data at ASCO 2026","url":"https://stock-news.laohu8.com/highlight/detail?id=2629302080","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2629302080?lang=en_us&edition=fundamental","pubTime":"2026-04-21 22:31","pubTimestamp":1776781888,"startTime":"0","endTime":"0","summary":"Bicycle Therapeutics scheduled interim results from Duravelo-2 studies of zelenectide pevedotin , including a pembrolizumab combination in first-line locally advanced or metastatic urothelial carcinoma, for presentation at ASCO 2026.Rapid oral presentation is set for June 1, covering previously untreated patients with locally advanced or metastatic urothelial carcinoma.Multiple posters on May 31 will provide updated findings from Duravelo-1 monotherapy and combination cohorts, focusing on previously treated metastatic urothelial carcinoma and cisplatin-ineligible first-line patients.Additional ASCO poster will outline quantitative work intended to support selection of an optimized BT8009 dose in locally advanced or metastatic urothelial carcinoma.Company plans to post presentation materials on its website on mornings of each session.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260421:nNDL4l1hsY:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","BCYC"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2628742073","title":"Bicycle Therapeutics publishes investor presentation on Bicycle molecule platform and oncology pipeline","url":"https://stock-news.laohu8.com/highlight/detail?id=2628742073","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2628742073?lang=en_us&edition=fundamental","pubTime":"2026-04-20 19:22","pubTimestamp":1776684154,"startTime":"0","endTime":"0","summary":"Bicycle Therapeutics highlighted cash and cash equivalents of USD 628.1 million as of Dec. 31, 2025, with expected financial runway into 2030.Lead program nuzefatide pevedotin  advanced into Phase 2 in pancreatic ductal adenocarcinoma.Pipeline update outlined radioligand programs targeting MT1-MMP and EphA2, including a 212Pb Bicycle radioconjugate candidate BT1702 in IND-enabling work.Partnered program ION826/AZD4063 targeting phospholamban gene remained in Phase 1 for cardiometabolic disease.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Bicycle Therapeutics plc published the original content used to generate this news brief on April 20, 2026, and is solely responsible for the information contained therein.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260420:nNDLbDbzS6:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BCYC","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2628742356","title":"Bicycle Therapeutics doses first patient in Phase 2 pancreatic cancer trial for nuzefatide pevedotin","url":"https://stock-news.laohu8.com/highlight/detail?id=2628742356","media":"Reuters","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2628742356?lang=en_us&edition=fundamental","pubTime":"2026-04-20 19:00","pubTimestamp":1776682832,"startTime":"0","endTime":"0","summary":"Bicycle Therapeutics reported Phase 1/2 combination results for nuzefatide pevedotin with nivolumab in previously treated metastatic urothelial cancer, with data already presented at AACR 2026.Early findings showed encouraging anti-tumor activity in patients whose tumors expressed EphA2, with tolerability described as differentiated versus prior EphA2-targeted approaches.Bicycle selected 8 mg/m every two weeks as preferred monotherapy dose based on dose-ranging work, positioning it for next-stage development.Enrollment started in March 2026 for a Phase 2 study in recurrent pancreatic ductal adenocarcinoma, with first patient dosed in April 2026.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260420:nNDL8jYMyF:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BCYC","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2627447089","title":"European Equities Traded in the US as ADRs Rise in Tuesday Trading","url":"https://stock-news.laohu8.com/highlight/detail?id=2627447089","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2627447089?lang=en_us&edition=fundamental","pubTime":"2026-04-14 23:05","pubTimestamp":1776179126,"startTime":"0","endTime":"0","summary":"European equities traded in the US as American depositary receipts rose late Tuesday morning with the S&P Europe Select ADR Index gaining 0.3% to 1,844.78.From continental Europe, the gainers were led by biopharmaceutical company Grifols  and internet browser company Opera , which rose 3.1% and 2.9%, respectively. They were followed by pharmaceutical company Novo Nordisk  and semiconductor company Sequans Communications , which were up 2.3% and 1.6%, respectively.The decliners from continental Europe were led by petroleum refiner Equinor  and biotech firm Evaxion , which fell 2.5% and 1.2%, respectively. They were followed by oil and gas company Eni  and pharmaceutical company Ascendis Pharma , which were down 1% and 0.5%, respectively.The gainers from the UK were led by biopharmaceutical companies Bicycle Therapeutics  and Biodexa Pharmaceuticals , which advanced 6.2% and 4.2%, respectively. They were followed by biopharmaceutical company NuCana  and cruise line operator Carnival , wh","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["DRIP","NVO","ERX","VDE","BTI","BK4139","PXJ","DBC","LU0320765646.SGD","SHEL","IXC","BK4082","LU2543165471.USD","SHEH","BK7104","LU0889565916.HKD","LU2236285917.USD","BK4007","LU0109394709.USD","DBE","GRFS","LU0006061336.USD","DIG","LU0098860793.USD","BK4023","CUK","BK4201","BK4532","USE","BK4141","BK7062","E","LU1162221912.USD","BDRX","BK4142","GUSH","EQNR","SLN","EVAX","LU0320765992.SGD","LU1093756325.SGD","LU0154236417.USD","BCYC","BK4585","SQNS","BK4075","LU0278409577.USD","LU0300736492.USD","OPRA","NVOX","DRLL","IE00BKVL7J92.USD","IEO","LU0300736062.USD","NCNA","NVOH","ASND","LU1093756168.USD","BK4588","IE00BZ1G4Q59.USD","BK4599","TRIB"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2627451298","title":"European Equities Traded in the US as American Depositary Receipts Start Week on Flat Note in Monday Trading","url":"https://stock-news.laohu8.com/highlight/detail?id=2627451298","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2627451298?lang=en_us&edition=fundamental","pubTime":"2026-04-13 23:04","pubTimestamp":1776092679,"startTime":"0","endTime":"0","summary":"European equities traded in the US as American depositary receipts began the week little changed late Monday morning, edging 0.02% higher to 1,822.16 on the S&P Europe Select ADR Index.From continental Europe, the gainers were led by biopharmaceutical company Cellectis  and telecommunications company Nokia , which advanced 26% and 9.3%, respectively. They were followed by furniture maker Natuzzi   and biotech firm Evaxion , which climbed 7.1% and 3.4%, respectively.The decliners from continental Europe were led by accommodations booking company trivago  and brewing company Anheuser-Busch InBev , which dropped 3.3% and 1.2%, respectively. They were followed by pharmaceutical company Sanofi  and lender Banco Santander , which were off 0.9% and 0.8%, respectively.The gainers from the UK were led by pharmaceutical company Silence Therapeutics  and biopharmaceutical company Mereo BioPharma Group , which rose 7% and 4.8%, respectively. They were followed by biopharmaceutical companies NuCana","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["TRVG","CUK","BK4207","BK4521","IE00BMPRXR70.SGD","BK4077","IE00BMPRXN33.USD","EVAX","IE00BFXG1179.USD","LNOK","BK4158","BUD","BK4020","NTZ","CLLS","BCS","SNY","BK4095","BK4585","BCYC","BDRX","AFG","BK7119","BK4117","BK4107","BK4547","NCNA","NOK","BK4139","MREO","SLN","BK4588","BUD.AU","SAN","BK7142","BK4505","SAN.AU","BK4082","BK4007","TRIB","BK4142"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2625942979","title":"Bicycle Therapeutics Is Maintained at Equal-Weight by Morgan Stanley","url":"https://stock-news.laohu8.com/highlight/detail?id=2625942979","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2625942979?lang=en_us&edition=fundamental","pubTime":"2026-04-08 21:39","pubTimestamp":1775655540,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/BCYC/analyst-ratings \n\n\n \n\n\n  (END) Dow Jones Newswires\n\n\n  April 08, 2026 09:39 ET (13:39 GMT)","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","BK4007","BK4539","LENZ","BCYC"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2625607689","title":"Bicycle Therapeutics COO Jennifer Scott Perry disposes of shares worth $6,803","url":"https://stock-news.laohu8.com/highlight/detail?id=2625607689","media":"Reuters","labels":["shareholding","insiderTrades"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2625607689?lang=en_us&edition=fundamental","pubTime":"2026-04-07 06:30","pubTimestamp":1775514647,"startTime":"0","endTime":"0","summary":"Bicycle Therapeutics COO Jennifer Scott Perry sold 1,408 ordinary shares on April 2-6.Sales were priced at USD 4.91-5.05 per share.Holdings fell to 92,464 ordinary shares following transactions.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Bicycle Therapeutics plc published the original content used to generate this news brief via EDGAR, the Electronic Data Gathering, Analysis, and Retrieval system operated by the U.S. Securities and Exchange Commission , on April 06, 2026, and is solely responsible for the information contained therein.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260406:nNDLyZXHK:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":"Bicycle Therapeutics COO Jennifer Scott Perry disposes of shares worth $6,803","news_tag":"shareholding,insiderTrades","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BCYC","BK4139"],"isVideo":false,"video":null,"gpt_icon":0}],"pageSize":20,"totalPage":4,"pageCount":2,"totalSize":64,"code":"91000000","status":"200"}]}}