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Amylyx Pharmaceuticals

38.66

-1.0000-2.52%

Post-market: 39.000.3400+0.88%19:55 EDT

Volume:4.64M

Turnover:182.75M

Market Cap:4.30B

PE:-27.02

High:41.14

Open:39.80

Low:38.35

Close:39.66

52wk High:41.14

52wk Low:8.46

Shares:111.19M

Float Shares:82.57M

Volume Ratio:0.53

T/O Rate:5.63%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-1.4309

EPS(LYR):-1.5305

ROE:-74.73%

ROA:-44.13%

PB:17.97

PE(LYR):-25.26

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Overview Company News Filings

Amylyx director Karen Firestone acquires $51,338 of common shares

Do HELIOS Data Shift Amylyx (AMLX) From ALS Setback To Broader Rare-Disease Strategy Reboot?

Simply Wall St.

Amylyx announces publication of Phase 2 open-label HELIOS trial data

Amylyx posts Phase 2 HELIOS data showing AMX0035 benefits in Wolfram syndrome

Amylyx Pharmaceuticals Announces Peer-Reviewed Publication of Phase 2 Open-Label Helios Trial Data for Amx0035 in the Journal of Clinical Investigation

THOMSON REUTERS

Wall Street Analysts Are Bullish on Top Healthcare Picks

Analysts Offer Insights on Healthcare Companies: Amylyx Pharmaceuticals Inc (AMLX), BioAge Labs, Inc. (BIOA) and Pharvaris (PHVS)

Stock Track | Amylyx Pharmaceuticals Plummets 8.16% Intraday on Wider-Than-Expected Q1 Loss

Amylyx Pharmaceuticals Inc reports results for the quarter ended March 31 - Earnings Summary

Amylyx Pharmaceuticals Q1 net loss widens more than expected on higher R&D costs

Earnings Flash (AMLX) Amylyx Posts Q1 Loss $0.37 a Share, vs. FactSet Est of $0.35 Loss

MT Newswires Live

Amylyx Pharma Q1 EPS $(0.37), Inline, Cash, Cash Equivalents, And Short-Term Investments Were $279.8M, With Expected Cash Runway into 2028

Benzinga Earnings

Amylyx Q1 net loss widens to $41.3 million

BRIEF-Amylyx Pharmaceuticals Q1 EPS USD -0.37 Vs. IBES Estimate USD -0.33

Amylyx Pharmaceuticals Inc - Cash Runway Expected to Fund Operations Into 2028

THOMSON REUTERS

Press Release: Amylyx Pharmaceuticals Reports First Quarter 2026 Financial Results

Calendar of U.S. Earnings Expected in the Week Ahead

Amylyx management participates in Bank of America Health Care Conference fireside chat

Amylyx Pharmaceuticals Announces U.S. Expanded Access Program for Adults With Post-Bariatric Hypoglycemia

THOMSON REUTERS

Amylyx Pharmaceuticals Inc - Avexitide Phase 3 Lucidity Trial Topline Data Readout Anticipated in Q3 2026

THOMSON REUTERS

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director Karen Firestone acquires $51,338 of common shares","url":"https://stock-news.laohu8.com/highlight/detail?id=2638822540","media":"Reuters","labels":["shareholding","insiderTrades","merge"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2638822540?lang=en_us&edition=fundamental","pubTime":"2026-05-27 04:00","pubTimestamp":1779825650,"startTime":"0","endTime":"0","summary":"Amylyx director Karen Firestone bought 3,800 common shares at USD 13.51 each.Firestone’s direct holding rose to 66,900 shares.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Amylyx Pharmaceuticals Inc. published the original content used to generate this news brief via EDGAR, the Electronic Data Gathering, Analysis, and Retrieval system operated by the U.S. Securities and Exchange Commission , on May 26, 2026, and is solely responsible for the information contained therein.","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260526:nNDL2zQkxG:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":"Amylyx director Karen Firestone acquires $51,338 of common shares","news_tag":"shareholding,insiderTrades,merge","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["AMLX","BK4007"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2637548453","title":"Do HELIOS Data Shift Amylyx (AMLX) From ALS Setback To Broader Rare-Disease Strategy Reboot?","url":"https://stock-news.laohu8.com/highlight/detail?id=2637548453","media":"Simply Wall St.","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2637548453?lang=en_us&edition=fundamental","pubTime":"2026-05-22 02:33","pubTimestamp":1779388401,"startTime":"0","endTime":"0","summary":"Amylyx Pharmaceuticals recently reported that 24- and 48-week results from its Phase 2 open-label HELIOS trial of AMX0035 in adults with Wolfram syndrome were published in The Journal of Clinical Investigation, showing improved pancreatic beta cell function, better glycemic control, and a consistent safety profile.\nBecause Wolfram syndrome affects only about 3,000 people in the U.S. with no FDA-approved treatments, these peer-reviewed data highlight AMX0035’s potential to address a rare,...","market":"nz","thumbnail":"https://images.simplywall.st/asset/industry/6121000-choice1-main-header/1585186685410","type":0,"news_type":0,"thumbnails":["https://images.simplywall.st/asset/industry/6121000-choice1-main-header/1585186685410"],"rights":{"source":"simplywall_highlight","url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-amlx/amylyx-pharmaceuticals/news/do-helios-data-shift-amylyx-amlx-from-als-setback-to-broader","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-amlx/amylyx-pharmaceuticals/news/do-helios-data-shift-amylyx-amlx-from-als-setback-to-broader","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"simplywall_highlight","symbols":["BK4007","AMLX"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2635317590","title":"Amylyx announces publication of Phase 2 open-label HELIOS trial data","url":"https://stock-news.laohu8.com/highlight/detail?id=2635317590","media":"TIPRANKS","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2635317590?lang=en_us&edition=fundamental","pubTime":"2026-05-16 01:48","pubTimestamp":1778867306,"startTime":"0","endTime":"0","summary":"Amylyx (AMLX) Pharmaceuticals announced that Week 24 and Week 48 results from the Phase 2 open-label HELIOS clinical trial of AMX0035, an oral, fix...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/amylyx-announces-publication-of-phase-2-open-label-helios-trial-data-thefly-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/amylyx-announces-publication-of-phase-2-open-label-helios-trial-data-thefly-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["AMLX","BK4007"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2635036780","title":"Amylyx posts Phase 2 HELIOS data showing AMX0035 benefits in Wolfram syndrome","url":"https://stock-news.laohu8.com/highlight/detail?id=2635036780","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2635036780?lang=en_us&edition=fundamental","pubTime":"2026-05-16 00:12","pubTimestamp":1778861536,"startTime":"0","endTime":"0","summary":"Amylyx Pharmaceuticals announced peer-reviewed publication of Week 24 and Week 48 results from Phase 2 open-label HELIOS trial of AMX0035 in adults with Wolfram syndrome; portions of data were previously presented at medical meetings.Results indicated stabilization or improvement across measures tied to disease progression, including pancreatic function, glucose control, vision, and overall symptom burden.Drug was generally well tolerated, consistent with earlier safety disclosures, with no treatment-related serious adverse events reported.Company is working with FDA on Phase 3 trial in Wolfram syndrome; additional longer-term HELIOS data are expected at an upcoming scientific meeting.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260515:nNDL5mHL1t:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4007","AMLX"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2635036222","title":"Amylyx Pharmaceuticals Announces Peer-Reviewed Publication of Phase 2 Open-Label Helios Trial Data for Amx0035 in the Journal of Clinical Investigation","url":"https://stock-news.laohu8.com/highlight/detail?id=2635036222","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2635036222?lang=en_us&edition=fundamental","pubTime":"2026-05-16 00:12","pubTimestamp":1778861520,"startTime":"0","endTime":"0","summary":null,"market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260515:nTUA5YCYBY:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4007","AMLX"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2634287427","title":"Wall Street Analysts Are Bullish on Top Healthcare Picks","url":"https://stock-news.laohu8.com/highlight/detail?id=2634287427","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2634287427?lang=en_us&edition=fundamental","pubTime":"2026-05-11 21:50","pubTimestamp":1778507414,"startTime":"0","endTime":"0","summary":"There’s a lot to be optimistic about in the Healthcare sector as 3 analysts just weighed in on Lipocine (LPCN), Amylyx Pharmaceuticals Inc (AMLX) a...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/wall-street-analysts-are-bullish-on-top-healthcare-picks-blurbs-news-160?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/wall-street-analysts-are-bullish-on-top-healthcare-picks-blurbs-news-160?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4112","AMLX","LABU","BK4588","BLSX","BK4137","BLSG","BK4585","XBI","BK4007","LPCN","LU0128526141.USD","BK4581","LU0029874061.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2634440448","title":"Analysts Offer Insights on Healthcare Companies: Amylyx Pharmaceuticals Inc (AMLX), BioAge Labs, Inc. (BIOA) and Pharvaris (PHVS)","url":"https://stock-news.laohu8.com/highlight/detail?id=2634440448","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2634440448?lang=en_us&edition=fundamental","pubTime":"2026-05-10 21:50","pubTimestamp":1778421041,"startTime":"0","endTime":"0","summary":"Analysts have been eager to weigh in on the Healthcare sector with new ratings on Amylyx Pharmaceuticals Inc (AMLX), BioAge Labs, Inc. (BIOA) and P...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/analysts-offer-insights-on-healthcare-companies-amylyx-pharmaceuticals-inc-amlx-bioage-labs-inc-bioa-and-pharvaris-phvs-blurbs-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/analysts-offer-insights-on-healthcare-companies-amylyx-pharmaceuticals-inc-amlx-bioage-labs-inc-bioa-and-pharvaris-phvs-blurbs-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["LU0029874061.USD","BK4137","AMLX","PHVS","HCSG","XBI","XLV","BIOA","BK4588","LU0128526141.USD","BK4007","BK4581","LABU","BK4585"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1195103077","title":"Stock 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Pharmaceuticals Inc AMLX.OQ reported a quarterly adjusted loss of 37 cents per share for the quarter ","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260507:nL8N41K2J8:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["AMLX","BK4007"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2633146434","title":"Amylyx Pharmaceuticals Q1 net loss widens more than expected on higher R&D costs","url":"https://stock-news.laohu8.com/highlight/detail?id=2633146434","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2633146434?lang=en_us&edition=fundamental","pubTime":"2026-05-07 19:22","pubTimestamp":1778152935,"startTime":"0","endTime":"0","summary":"Amylyx Pharmaceuticals Q1 net loss widens more than expected on higher R&D costsOverviewU.S. biotech firm's Q1 net loss widened, missing analyst expectationsQ1 adjusted EPS missed analyst consensusHig","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260507:nL1N41K0L4:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["AMLX","BK4007"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2633466001","title":"Earnings Flash (AMLX) Amylyx Posts Q1 Loss $0.37 a Share, vs. FactSet Est of $0.35 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or USD 0.42 per share, a year earlier.R&D expense rose to USD 27.6 million from USD 22.1 million, driven by higher avexitide development spending; results also included USD 4 million of milestone payments to Gubra tied to selection and handover of AMX0318.SG&A edged up to USD 16.2 million from USD 15.7 million on higher consulting and professional services.Cash, cash equivalents, and short-term investments fell to USD 279.8 million at March 31 from USD 317 million at year-end, with runway expected to fund operations through potential avexitide commercialization and into 2028.Enrollment completed in Phase 3 LUCIDITY trial of avexitide in post-bariatric hypoglycemia, with topline data anticipated in Q3 2026; management said regulatory and commercial readiness work has started ahead of a potential 2027 launch if 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Q1 operating income USD -43.779 million vs. IBES estimate USD -41.6 million","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260507:nPLXF0BDD8:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"express","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["AMLX","BK4007"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2633145695","title":"Amylyx Pharmaceuticals Inc - Cash Runway Expected to Fund Operations Into 2028","url":"https://stock-news.laohu8.com/highlight/detail?id=2633145695","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2633145695?lang=en_us&edition=fundamental","pubTime":"2026-05-07 19:00","pubTimestamp":1778151603,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260507:nPLXF0BDD8:6","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4007","AMLX"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2633014594","title":"Press Release: Amylyx Pharmaceuticals Reports First Quarter 2026 Financial Results","url":"https://stock-news.laohu8.com/highlight/detail?id=2633014594","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2633014594?lang=en_us&edition=fundamental","pubTime":"2026-05-07 19:00","pubTimestamp":1778151600,"startTime":"0","endTime":"0","summary":"--  Topline data readout from Phase 3 LUCIDITY clinical trial of avexitide. in post-bariatric hypoglycemia on track; anticipated in Q3 2026. --  Cash runway expected to fund operations through potential avexitide. Amylyx Pharmaceuticals, Inc.   today reported financial and business results for the first quarter ended March 31, 2026.\"With enrollment complete in the pivotal Phase 3 LUCIDITY clinical trial, we have a clear line of sight to the anticipated Q3 topline data readout, bringing us one step closer to the potential of delivering the first approved therapy for the post-bariatric hypoglycemia community,\" said Joshua Cohen and Justin Klee, Co-CEOs of Amylyx. \"We understand the devastating daily burden of this condition and are operating with a sense of urgency to advance our program. We have initiated regulatory and commercial readiness activities to help ensure we are positioned to move swiftly following LUCIDITY topline data. 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