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Actuate Therapeutics Inc

1.27

+0.04003.25%

Post-market: 1.290.0200+1.57%19:30 EDT

Volume:275.82K

Turnover:346.30K

Market Cap:30.39M

PE:-1.43

High:1.34

Open:1.22

Low:1.18

Close:1.23

52wk High:9.22

52wk Low:0.9000

Shares:23.93M

Float Shares:8.60M

Volume Ratio:0.83

T/O Rate:3.21%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-0.8859

EPS(LYR):-1.0574

ROE:-553.75%

ROA:-213.40%

PB:30.72

PE(LYR):-1.20

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Overview Company News Filings

Actuate Therapeutics Q1 net loss narrows 10.94% to $5.63 million

Actuate Therapeutics Inc expected to post a loss of 22 cents a share - Earnings Preview

Analysts Are Bullish on These Healthcare Stocks: Actuate Therapeutics, Inc. (ACTU), Agios Pharma (AGIO)

Actuate Therapeutics receives FDA clearance for oral elraglusib study

Actuate Therapeutics adds Martin Huber to board of directors

Actuate Therapeutics wins FDA IND clearance for oral elraglusib cancer trial

Actuate Therapeutics Inc - FDA Clears Ind for Phase 1/2 Study of Oral Elraglusib in Advanced Cancer Patients

THOMSON REUTERS

Actuate Therapeutics Inc - Elraglusib Plus Ras Inhibitor Preclinical Results Expected in Mid-2026

THOMSON REUTERS

Actuate Therapeutics Announces FDA Clearance of Ind for Oral Elraglusib and Strategic Initiatives to Advance the Elraglusib Development Program

THOMSON REUTERS

Press Release: Actuate Therapeutics Announces FDA Clearance of IND for Oral Elraglusib and Strategic Initiatives to Advance the Elraglusib Development Program

Actuate Therapeutics director Martin H. Huber Jr files initial beneficial ownership statement

Actuate Therapeutics Adds Oncology Expert to Board Leadership

Actuate Therapeutics names Martin Huber to board as independent director

Press Release: Actuate Therapeutics Announces Key Appointment of Industry Veteran to Board of Directors

Actuate Therapeutics Price Target Maintained With a $15.00/Share by HC Wainwright & Co.

Health Rounds: Actuate Therapeutics drug improves survival odds in pancreatic cancer trial

Why Did Actuate Therapeutics (ACTU) Stock Jump Over 14% After Hours?

B. Riley Cuts Actuate Therapeutics Price Target to $8 From $20, Maintains Buy Rating

MT Newswires Live

Actuate says elraglusib plus chemo lifts median survival 40% in phase 2 pancreatic trial

Actuate Therapeutics Announces Nature Medicine Publication of Clinical Trial Results Showing Doubling of the Rate of Survival with Elraglusib Plus Chemotherapy in Previously Untreated Metastatic Pancreatic Ductal Adenocarcinoma

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While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Actuate Therapeutics Inc. published the original content used to generate this news brief on May 11, 2026, and is solely responsible for the information contained therein.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260511:nNDL275FtH:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"executive","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["ACTU","SNDX","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2634880962","title":"Actuate Therapeutics wins FDA IND clearance for oral elraglusib cancer trial","url":"https://stock-news.laohu8.com/highlight/detail?id=2634880962","media":"Reuters","labels":["policyRegulatory"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2634880962?lang=en_us&edition=fundamental","pubTime":"2026-05-11 19:04","pubTimestamp":1778497477,"startTime":"0","endTime":"0","summary":"Actuate Therapeutics received FDA clearance of an IND for oral elraglusib.Phase 1/2 trial in advanced solid tumors planned to start in 2H 2026, targeting higher drug exposure than IV formulation.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260511:nNDL8sjZ8f:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":null,"news_tag":"policyRegulatory","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4112","SG9999014039.USD","BK4139","IE00BGHQF748.EUR","IE00BN0W2V16.EUR","LU2210149790.SGD","LU2095319765.USD","LU2210150020.SGD","IE00B64PRP62.GBP","LU0314104364.USD","NDAQ","SG9999014005.SGD","IE00B3QW5Z07.USD","IE00BN0W2W23.USD","SG9999014013.SGD","BK4585","SG9999014021.USD","IE00BN0W2T93.GBP","ACTU","IE00BKPKM429.USD","BK4588"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2634288486","title":"Actuate Therapeutics Inc - FDA Clears Ind for Phase 1/2 Study of Oral Elraglusib in Advanced Cancer Patients","url":"https://stock-news.laohu8.com/highlight/detail?id=2634288486","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2634288486?lang=en_us&edition=fundamental","pubTime":"2026-05-11 19:00","pubTimestamp":1778497201,"startTime":"0","endTime":"0","summary":null,"market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260511:nTUAFKBM0:3","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","ACTU"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2634288454","title":"Actuate Therapeutics Inc - Elraglusib Plus Ras Inhibitor Preclinical Results Expected in Mid-2026","url":"https://stock-news.laohu8.com/highlight/detail?id=2634288454","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2634288454?lang=en_us&edition=fundamental","pubTime":"2026-05-11 19:00","pubTimestamp":1778497201,"startTime":"0","endTime":"0","summary":null,"market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260511:nTUAFKBM0:2","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","ACTU"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2634288195","title":"Actuate Therapeutics Announces FDA Clearance of Ind for Oral Elraglusib and Strategic Initiatives to Advance the Elraglusib Development Program","url":"https://stock-news.laohu8.com/highlight/detail?id=2634288195","media":"THOMSON REUTERS","labels":["event"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2634288195?lang=en_us&edition=fundamental","pubTime":"2026-05-11 19:00","pubTimestamp":1778497201,"startTime":"0","endTime":"0","summary":null,"market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260511:nTUAFKBM0:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"event","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["ACTU","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2634828842","title":"Press Release: Actuate Therapeutics Announces FDA Clearance of IND for Oral Elraglusib and Strategic Initiatives to Advance the Elraglusib Development Program","url":"https://stock-news.laohu8.com/highlight/detail?id=2634828842","media":"Dow Jones","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2634828842?lang=en_us&edition=fundamental","pubTime":"2026-05-11 19:00","pubTimestamp":1778497200,"startTime":"0","endTime":"0","summary":"-- Elraglusib oral tablet formulation to drive next-phase clinical. -- FDA cleared IND for Phase 1/2 study of oral elraglusib in advanced cancer. patients, with focus on metastatic melanoma, NSCLC, colorectal, and. pancreatic cancers with initiation planned for 2H 2026. To support this initiative, the Company recently received Investigational New Drug  clearance from FDA to conduct a Phase 1/2 study designed to demonstrate that a higher overall exposure to elraglusib can be achieved with the oral formulation compared to the IV formulation. The study will evaluate the safety and potential efficacy of the oral formulation as a monotherapy in solid tumor patients, including those with metastatic melanoma, NSCLC, colorectal, and pancreatic cancers, based on evidence of efficacy of the IV formulation in prior clinical studies and machine learning therapeutic target analyses.\"Advancing the elraglusib oral tablet is an important element to the success of our overall development strategy,\" sai","market":"sh","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LABU","BK4218","MTD","BK4139","BK4585","LU1721428933.USD","BK4567","BK4081","EMA","LU1093756325.SGD","LU2413666699.HKD","LU0347712357.USD","IE00BYQQ9H92.USD","BK4181","ACTU","LU2413666426.HKD","IE00BFXG0V08.USD","IND","PK","BK4533","BK4548","IE00B5TLWC47.USD","BK4588","BK4121","LU1093756168.USD","LU2211817866.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2633415935","title":"Actuate Therapeutics director Martin H. Huber Jr files initial beneficial ownership statement","url":"https://stock-news.laohu8.com/highlight/detail?id=2633415935","media":"Reuters","labels":["executive"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2633415935?lang=en_us&edition=fundamental","pubTime":"2026-05-07 04:00","pubTimestamp":1778097653,"startTime":"0","endTime":"0","summary":"Actuate Therapeutics disclosed director Martin H. Huber Jr. received 30,000 non-qualified stock options exercisable at USD 3, expiring May 1, 2036.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Actuate Therapeutics Inc. published the original content used to generate this news brief via EDGAR, the Electronic Data Gathering, Analysis, and Retrieval system operated by the U.S. Securities and Exchange Commission , on May 06, 2026, and is solely responsible for the information contained therein.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260506:nNDL3R6ZVy:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"executive","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["ACTU","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2633935134","title":"Actuate Therapeutics Adds Oncology Expert to Board Leadership","url":"https://stock-news.laohu8.com/highlight/detail?id=2633935134","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2633935134?lang=en_us&edition=fundamental","pubTime":"2026-05-06 22:21","pubTimestamp":1778077276,"startTime":"0","endTime":"0","summary":"Actuate Therapeutics, Inc. ( ($ACTU) ) just unveiled an update. On May 1, 2026, Actuate Therapeutics, Inc. expanded its Board of Directors from sev...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/company-announcements/actuate-therapeutics-adds-oncology-expert-to-board-leadership?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/company-announcements/actuate-therapeutics-adds-oncology-expert-to-board-leadership?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["ACTU","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2633355341","title":"Actuate Therapeutics names Martin Huber to board as independent director","url":"https://stock-news.laohu8.com/highlight/detail?id=2633355341","media":"Reuters","labels":["executive"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2633355341?lang=en_us&edition=fundamental","pubTime":"2026-05-06 20:45","pubTimestamp":1778071514,"startTime":"0","endTime":"0","summary":"Actuate Therapeutics appointed Martin Huber, MD, as independent director, effective immediately.Huber most recently served as president and CEO of Mersana Therapeutics until its acquisition by Day One Pharmaceuticals in January 2026.He previously held senior R&D leadership roles at Xilio Therapeutics, TESARO, including chief medical officer.Board addition comes as company advances elraglusib across multiple cancer indications toward registration studies, commercialization.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260506:nNDL3DJdXs:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"executive","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SGXZ57979304.SGD","SG9999013999.USD","LU1400636657.SGD","LU2210150020.SGD","LU1645745479.HKD","LU0557290698.USD","SG9999014039.USD","IE0034235071.USD","SG9999014013.SGD","LU1228905037.USD","IE00BKPKM429.USD","LU0545562505.USD","LU2646069778.SGD","BK4588","IE00B64PRP62.GBP","LU0225284248.USD","ACTU","LU2089984988.USD","LU0161305163.EUR","GSK.UK","LU0109981661.USD","LU0321505439.SGD","LU1046248800.SGD","SG9999014005.SGD","LU0225283273.USD","NDAQ","LU1481600234.SGD","LU0306806265.USD","LU0203347892.USD","LU1983299246.USD","LU0971552830.HKD","LU2095319765.USD","LU1302929846.USD","LU1098665638.USD","LU0971552673.USD","LU2468319806.SGD","LU1064927863.SGD","LU1309081286.SGD","IE00BQJZX424.USD","LU1202635105.USD","LU0225771236.USD","LU1035777561.USD","IE00BWDBJ516.SGD","BK4585","LU0575583348.USD","IE00B3T34201.USD","IE00BN0W2T93.GBP","LU0203345920.USD","IE00BN0W2W23.USD","LU0987226296.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2633355691","title":"Press Release: Actuate Therapeutics Announces Key Appointment of Industry Veteran to Board of Directors","url":"https://stock-news.laohu8.com/highlight/detail?id=2633355691","media":"Dow Jones","labels":["executive"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2633355691?lang=en_us&edition=fundamental","pubTime":"2026-05-06 20:45","pubTimestamp":1778071500,"startTime":"0","endTime":"0","summary":"CHICAGO and FORT WORTH, Texas, May 06, 2026  -- Actuate Therapeutics, Inc.  , a clinical-stage biopharmaceutical company focused on developing therapies for the treatment of high-impact, difficult-to-treat cancers, today announced the appointment of Martin Huber, MD, as an Independent Director, effective immediately. This appointment strengthens Actuate's leadership team as it advances elraglusib across multiple difficult-to-treat cancer indications toward registration studies and commercialization.Actuate is a clinical-stage biopharmaceutical company focused on developing therapies for the treatment of high-impact, difficult-to-treat cancers. Actuate's lead investigational drug, elraglusib , targets molecular pathways in cancer that are involved in promoting tumor growth and resistance to conventional cancer drugs such as chemotherapy through the inhibition of nuclear factor kappa-light-chain-enhancer of activated B cells  and DNA Damage Response . Elraglusib may also mediate anti-tum","market":"sh","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"executive","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["ACTU","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2629649046","title":"Actuate Therapeutics Price Target Maintained With a $15.00/Share by HC Wainwright & Co.","url":"https://stock-news.laohu8.com/highlight/detail?id=2629649046","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2629649046?lang=en_us&edition=fundamental","pubTime":"2026-04-22 20:09","pubTimestamp":1776859740,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/ACTU/analyst-ratings \n\n\n \n\n\n  (END) Dow Jones Newswires\n\n\n  April 22, 2026 08:09 ET (12:09 GMT)","market":"other","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["ACTU"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2629050857","title":"Health Rounds: Actuate Therapeutics drug improves survival odds in pancreatic cancer trial","url":"https://stock-news.laohu8.com/highlight/detail?id=2629050857","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2629050857?lang=en_us&edition=fundamental","pubTime":"2026-04-22 04:12","pubTimestamp":1776802353,"startTime":"0","endTime":"0","summary":"Health Rounds: Actuate Therapeutics drug improves survival odds in pancreatic cancer trialHealth Rounds is published on Tuesdays and Thursdays. Think your friend or colleague should know about us?Forward this newsletter to them. They can also subscribe hereBy Nancy LapidApril 21  - Hello Health Rounds readers!","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260421:nL1N4140ZO:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","ACTU"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2627267167","title":"Why Did Actuate Therapeutics (ACTU) Stock Jump Over 14% After Hours?","url":"https://stock-news.laohu8.com/highlight/detail?id=2627267167","media":"Benzinga","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2627267167?lang=en_us&edition=fundamental","pubTime":"2026-04-16 15:34","pubTimestamp":1776324840,"startTime":"0","endTime":"0","summary":"Actuate Therapeutics shares surged 14.41% after-hours after Nature Medicine published Phase 2 data showing elraglusib plus chemotherapy improved overall survival in metastatic pancreatic cancer.","market":"us","thumbnail":"https://cdn.benzinga.com/files/images/story/2026/04/16/Telemedicine-And-Human-Pancreas-Recovery.jpeg?optimize=medium&dpr=2&auto=webp&width=260","type":0,"news_type":0,"thumbnails":["https://cdn.benzinga.com/files/images/story/2026/04/16/Telemedicine-And-Human-Pancreas-Recovery.jpeg?optimize=medium&dpr=2&auto=webp&width=260"],"rights":{"source":"benzinga_hot_news","url":"https://www.benzinga.com/markets/equities/26/04/51850128/why-did-actuate-therapeutics-actu-stock-jump-over-14-after-hours","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.benzinga.com/markets/equities/26/04/51850128/why-did-actuate-therapeutics-actu-stock-jump-over-14-after-hours","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"benzinga_hot_news","symbols":["BK4150","ACTU","BK4139","RSI"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2627280850","title":"B. Riley Cuts Actuate Therapeutics Price Target to $8 From $20, Maintains Buy Rating","url":"https://stock-news.laohu8.com/highlight/detail?id=2627280850","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2627280850?lang=en_us&edition=fundamental","pubTime":"2026-04-15 21:27","pubTimestamp":1776259674,"startTime":"0","endTime":"0","summary":"Actuate Therapeutics (ACTU) has an average rating of Buy and mean price target of $16.50, according to analysts polled by FactSet.(MT Newswires covers equity, commodity and economic research from majo","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["ACTU"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2627449339","title":"Actuate says elraglusib plus chemo lifts median survival 40% in phase 2 pancreatic trial","url":"https://stock-news.laohu8.com/highlight/detail?id=2627449339","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2627449339?lang=en_us&edition=fundamental","pubTime":"2026-04-14 20:46","pubTimestamp":1776170770,"startTime":"0","endTime":"0","summary":"Actuate reported publication of randomized Phase 2 trial results in Nature Medicine for elraglusib with standard first-line chemotherapy in previously untreated metastatic pancreatic ductal adenocarcinoma.Data were already presented via peer-reviewed publication, showing improved survival outcomes versus chemotherapy alone.Survival benefit held in poorer-prognosis subgroups, supporting potential differentiation in a setting with limited progress from immunotherapies.Study findings also pointed to an immunomodulatory effect, suggesting a broader combination strategy beyond chemotherapy backbones.Safety profile was described as generally manageable, reducing near-term execution risk for continued clinical development.","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260414:nNDL47BBwD:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU2210149790.SGD","SG9999014021.USD","IE00BN0W2W23.USD","SG9999014039.USD","IE00BKPKM429.USD","NDAQ","IE00BGHQF748.EUR","ACTU","BK4585","LU2095319765.USD","LU2210150020.SGD","IE00B3QW5Z07.USD","BK4139","SG9999014005.SGD","LU0314104364.USD","SG9999014013.SGD","BK4588","BK4112","IE00B64PRP62.GBP","IE00BN0W2T93.GBP","IE00BN0W2V16.EUR"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2627493124","title":"Actuate Therapeutics Announces Nature Medicine Publication of Clinical Trial Results Showing Doubling of the Rate of Survival with Elraglusib Plus Chemotherapy in Previously Untreated Metastatic Pancreatic Ductal Adenocarcinoma","url":"https://stock-news.laohu8.com/highlight/detail?id=2627493124","media":"GlobeNewswire","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2627493124?lang=en_us&edition=fundamental","pubTime":"2026-04-14 20:45","pubTimestamp":1776170700,"startTime":"0","endTime":"0","summary":"Median overall survival increased by >40% in elraglusib arm compared to the control arm, with a 1-year survival rate of 44% in the elraglusib arm versus 22% in the control arm18-month survival rate >2","market":"sh","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.globenewswire.com/news-release/2026/04/14/3273413/0/en/Actuate-Therapeutics-Announces-Nature-Medicine-Publication-of-Clinical-Trial-Results-Showing-Doubling-of-the-Rate-of-Survival-with-Elraglusib-Plus-Chemotherapy-in-Previously-Untrea.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["ACTU","BK4139"],"isVideo":false,"video":null,"gpt_icon":0}],"pageSize":20,"totalPage":3,"pageCount":2,"totalSize":56,"code":"91000000","status":"200"}]}}