Press Release: Ascendis Pharma Reports First Quarter 2026 Financial Results

Dow Jones
May 07

- Q1 2026 revenue of EUR197 million for YORVIPATH$(R)$ and EUR44 million for SKYTROFA(R)

- More than 1,000 new patient enrollments for YORVIPATH in the U.S. in Q1

- As of May 1, more than 60 YUVIWEL(R) enrollments since early April U.S. commercial launch

- Entered into agreement to sell Rare Pediatric Disease Priority Review Voucher for $187.5 million

- Conference call today at 8:00 am ET

COPENHAGEN, Denmark, May 07, 2026 (GLOBE NEWSWIRE) -- Ascendis Pharma A/S (Nasdaq: ASND) today announced financial results for the first quarter ended March 31, 2026, and provided a business update.

"The FDA approval of YUVIWEL, our third consecutive TransCon product, and the robust patient uptake for YORVIPATH are cementing our position as a leading global biopharma," said Jan Mikkelsen, President and Chief Executive Officer of Ascendis Pharma. "Our strong focus on science and making a meaningful difference for patients will continue to be the fundamental driver for our success."

Select Highlights & Anticipated 2026 Milestones

   -- YORVIPATH(palopegteriparatide, developed as TransCon PTH) 
 
          -- YORVIPATH revenue for the first quarter of 2026 totaled EUR197 
             million, which for the U.S. includes normal seasonality and the 
             temporary impact of additional patients supported by free drug, as 
             well as a one-time impact in Europe Direct related to expanded 
             market access. 
 
          -- In the U.S., more than 1,000 new patient enrollments in the first 
             quarter of 2026. 
 
          -- As of March 31, 2026, more than 6,300 unique patient enrollments 
             by more than 2,700 prescribing healthcare providers since launch 
             in the U.S. 
 
          -- Outside the U.S., continued expansion of commercial launches with 
             full reimbursement. Now available commercially or through named 
             patient programs in 35 countries. 
 
          -- Ongoing label expansion trials through PaTHway60 (adults) and 
             PaTHway Adolescent. 
   -- YUVIWEL (navepegritide, developed as TransCon CNP) 
 
          -- Received U.S. Food & Drug Administration (FDA) accelerated 
             approval, indicated to increase linear growth in children 2 years 
             of age and older with achondroplasia with open epiphyses. 
 
          -- The FDA granted orphan drug exclusivity for YUVIWEL, which will 
             run through February 27, 2033. 
 
          -- As of May 1, 2026, more than 60 unique patient enrollments by more 
             than 35 prescribing healthcare providers since U.S. commercial 
             availability in April 2026. 
 
          -- Marketing Authorisation Application remains under review by the 
             European Medicines Agency, with a decision anticipated in the 
             fourth quarter of 2026. 
          -- Label expansion trial in infants with achondroplasia, reACHin, is 
             ongoing with enrollment completion anticipated in the third 
             quarter of 2026. 
 
          -- Phase 3 trial planned to investigate TransCon CNP monotherapy for 
             the treatment of hypochondroplasia in the second half of the year. 
   -- SKYTROFA(lonapegsomatropin, developed as TransCon hGH) 
 
          -- SKYTROFA revenue for the first quarter of 2026 totaled EUR44 
             million. 
 
          -- Announced Week 52 data from the Phase 2 New InsiGHTS Trial in 
             Turner syndrome that demonstrated comparable efficacy and safety 
             to daily somatropin. 
 
          -- Ongoing Phase 3 HighLiGHts basket trial across a range of 
             established growth disorders including idiopathic short stature 
             (ISS), SHOX deficiency, Turner syndrome, and small for gestational 
             age $(SGA)$. 
 
   -- TransCon CNP + TransCon hGH Combination Therapy(navepegritide plus 
      lonapegsomatropin) 
 
          -- Announced Phase 2 COACH Trial Week 52 topline results 
             demonstrating mean annualized growth velocity that exceeded the 
             97th percentile of average stature children, improvements in body 
             proportionality, and a safety profile consistent with TransCon CNP 
             and TransCon hGH monotherapies. 
 
          -- Announced additional Week 52 results from COACH demonstrating 
             meaningful benefits beyond linear growth, including improvements 
             in spinal canal dimensions and lower limb alignment, along with 
             unprecedented improvements in arm span compared to monotherapy. 
 
          -- Interim Week 78 data from COACH expected in the second quarter of 
             2026 with Week 104 data expected around year end. 
 
   -- Oncology Program(onvapegleukin alfa) 
 
          -- In the ongoing Phase 1/2 IL-BELIEVE Trial, TransCon IL-2 
             <BETA>/<GAMMA> in combination with paclitaxel demonstrated 
             improved median overall survival (OS) up to 10 months from 6-7 
             months for historical controls, with a generally well-tolerated 
             safety profile in patients with late-stage platinum-resistant 
             ovarian cancer, validating the science behind TransCon IL-2 
             <BETA>/<GAMMA>. 
 
          -- As further internal oncology development does not align with our 
             strategic focus, we have decided to discontinue internal 
             development of TransCon IL-2 <BETA>/<GAMMA> in Oncology and will 
             explore other ways to maximize the value of this asset. 

Key Financial Highlights

   -- Total revenue for the first quarter of 2026 was EUR247 million, compared 
      to EUR101 million during the same period in 2025. The year-over-year 
      increase in revenue was primarily attributable to an increase in product 
      revenue from YORVIPATH. 
 
   -- Operating profit for the first quarter of 2026 totaled EUR25 million, 
      reflecting a margin of 10.1%. On a non-IFRS basis, operating profit was 
      EUR55 million*, reflecting a margin of 22.4%*. 
 
   -- Net profit for the first quarter of 2026 totaled EUR629 million, or 
      EUR9.75 per diluted share, including the recognition of previously 
      unrecognized deferred tax assets of EUR679 million. On a non-IFRS basis, 
      net profit was EUR18 million*, or EUR0.27 per diluted share*. 
 
   -- As of March 31, 2026, Ascendis Pharma had cash and cash equivalents 
      totaling EUR573 million, which includes the impact of repurchases under 
      the previously announced share repurchase program of EUR52 million and 
      the net settlement of certain Restricted Stock Units for EUR8 million, 
      compared to cash and cash equivalents totaling EUR616 million as of 
      December 31, 2025. 
 
   -- Subsequent to March 31, 2026: 
 
          -- On April 20, 2026, the Company's ordinary shares commenced trading 
             on The Nasdaq Global Select Market, replacing the prior listing of 
             American Depositary Shares (ADSs). 
 
          -- On May 6, 2026, Ascendis redeemed all $575 million aggregate 
             principal amount of its outstanding 2.25% convertible notes due 
             2028. Within the redemption period, all holders of the convertible 
             notes surrendered their notes for conversion, whereupon the 
             Company delivered 3,635,813 ordinary shares, together with cash in 
             lieu of any fractional shares. The conversion resulted in the 
             settlement of the current liabilities of convertible notes, 
             comprising borrowings and derivative liabilities totaling EUR733 
             million as of March 31, 2026. The carrying amount as of the 
             settlement date will be reclassified to equity in the second 
             quarter of 2026. 
 
          -- Entered into agreement to sell its Rare Pediatric Disease Priority 
             Review Voucher (PRV) to an undisclosed buyer for $187.5 million in 
             cash, before transaction-related expenses. The PRV was awarded by 
             the FDA upon approval of YUVIWEL in February 2026. The transaction 
             is subject to customary closing conditions and is expected to 
             close in the second quarter of 2026. 

* See "Non-IFRS Financial Measures" below for definitions of these non-IFRS measures and a reconciliation to the most directly comparable IFRS measures.

First Quarter 2026 Financial Results

Total revenue for the first quarter of 2026 was EUR247 million, compared to EUR101 million during the same period in 2025. The year-over-year increase in revenue was primarily attributable to an increase in product revenue from YORVIPATH.

 
 
Total Revenue                    Three Months Ended 
 (In EUR'000s)                        March 31, 
                                  2026       2025 
Revenue 
Commercial products               240,853     96,028 
Services and clinical supply        5,110      3,524 
Licenses                              638      1,402 
Total revenue                     246,601    100,954 
                                =========  ========= 
 
 
 
Revenue from Commercial Products           Three Months Ended 
 (In EUR'000s)                                  March 31, 
                                          -------------------- 
                                             2026       2025 
 
 
 
 
 
Revenue from commercial products 
 
 
 
 
 
YORVIPATH(R)                                 196,896    44,688 
 
 
 
 
 
SKYTROFA(R)                                   43,957    51,340 
 
 
 
 
 
Total revenue from commercial products       240,853    96,028 
                                          ==========  ======== 
 
 
 
 
 
 
 

Research and development expenses for the first quarter of 2026 were EUR59 million, compared to EUR87 million during the same period in 2025. The decrease was driven primarily by the completion of certain clinical trials and development activities within our Endocrinology Rare Disease and Oncology pipeline and the first quarter of 2026 being positively impacted by a reversal of prior period write-downs of pre-launch inventories related to YUVIWEL.

Selling, general, and administrative expenses for the first quarter of 2026 were EUR145 million, compared to EUR101 million during the same period in 2025. The increase was primarily due to the impact from commercial expansion, including global launch activities.

Total operating expenses for the first quarter of 2026 were EUR204 million compared to EUR188 million during the same period in 2025.

Operating profit for the first quarter of 2026 was EUR25 million, compared to an operating loss of EUR104 million during the same period in 2025. The increase was primarily driven by the increase in product revenue.

Net finance expenses for the first quarter of 2026 were EUR63 million, compared to EUR16 million during the same period in 2025. The increase was primarily driven by non-cash fair-value remeasurement of derivative liabilities associated with our convertible notes.

Income taxes for the first quarter of 2026 included the recognition of previously unrecognized deferred tax assets of EUR679 million.

For the first quarter of 2026, Ascendis Pharma reported net profit of EUR629 million, or EUR10.20 per share basic and EUR9.75 per share (diluted), compared to a net loss of EUR95 million, or EUR1.58 per share (basic and diluted), for the same period in 2025. Net profit for the first quarter of 2026 included the recognition of previously unrecognized deferred tax assets of EUR679 million.

Cash flows used in operating activities for the first quarter of 2026 were EUR8 million compared to EUR14 million used during the same period in 2025. The change primarily reflects the prior-year period benefiting from the $100 million upfront payment received under our exclusive license agreement with Novo Nordisk, which did not recur in the current period, while the current period reflects improved operating performance offset by working capital build.

As of March 31, 2026, Ascendis Pharma had cash and cash equivalents totaling EUR573 million, compared to EUR616 million as of December 31, 2025. As of March 31, 2026, Ascendis Pharma had 62,376,846 ordinary shares outstanding, including 265,251 held by the Company.

Beginning with the first quarter of 2026, Ascendis Pharma is introducing supplemental non-IFRS financial measures that management believes will help investors evaluate the Company's underlying operating performance from period to period and enhance comparability against peer companies. The non-IFRS measures presented are not a substitute for, and should be considered together with, the comparable IFRS measures. See the table below on page 14 for specific reconciling items.

For the first quarter of 2026, non-IFRS operating profit was EUR55 million, compared to a non-IFRS operating loss of EUR79 million for the same period in 2025.

For the first quarter of 2026, non-IFRS net profit was EUR18 million, or EUR0.27 earnings per diluted share, compared to a non-IFRS net loss of EUR73 million, or EUR1.22 loss per diluted share, for the same period in 2025.

Conference Call and Webcast Information

Ascendis Pharma will host a conference call and webcast today at 8:00 am Eastern Time $(ET)$ to discuss its first quarter 2026 financial results.

Those who would like to participate may access the live webcast here, or register in advance for the teleconference here. The link to the live webcast will also be available on the Investors & News section of the Ascendis Pharma website at https://investors.ascendispharma.com. A replay of the webcast will be available in this section of the Ascendis Pharma website shortly after the conclusion of the event for 30 days.

About Ascendis Pharma A/S

Ascendis Pharma is a global biopharmaceutical company focused on applying our innovative TransCon technology platform to make a meaningful difference for patients. Guided by our core values of Patients, Science, and Passion, and following our algorithm for product innovation, we apply TransCon to develop new therapies that demonstrate best-in-class potential to address unmet medical needs. Ascendis is headquartered in Copenhagen, Denmark, and has additional facilities in Europe and the United States. Please visit ascendispharma.com to learn more.

Forward-Looking Statements

This press release contains forward-looking statements that involve substantial risks and uncertainties. All statements, other than statements of historical facts, included in this press release regarding Ascendis' future operations, plans and objectives of management are forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. Examples of such statements include, but are not limited to, statements relating to (i) Ascendis' evolution into a leading global biopharma, (ii) Ascendis' strong focus on science and making a meaningful difference for patients as the fundamental driver for success, (iii) anticipated timing of a regulatory decision from the European Medicines Agency, (iv) anticipated timing and plans of clinical trials and development activities, (v) Ascendis' ability to apply its TransCon technology platform to make a meaningful difference for patients and (vi) Ascendis' use of TransCon to create new and potentially best-in-class therapies. Ascendis may not actually achieve the plans, carry out the intentions or meet the expectations or projections disclosed in the forward-looking statements and you should not place undue reliance on these forward-looking statements. Actual results or events could differ materially from the plans, intentions, expectations and projections disclosed in the forward-looking statements. Various important factors could cause actual results or events to differ materially from the forward-looking statements that Ascendis makes, including, without limitation: dependence on third--party manufacturers, distributors, and service providers for Ascendis' products and product candidates; risks related to regulatory review and approval, including the possibility of delays, requests for additional data or analyses, restrictions or limitations on use, approval with labeling that is more limited than expected, or failure to obtain approval in the United States, European Union, or other jurisdictions; clinical development risks, including that results from ongoing or future trials may not confirm earlier data; unforeseen safety or efficacy findings in development programs or on--market products; manufacturing, supply chain, quality, or logistics issues that could delay development or commercialization; unforeseen expenses related to commercialization of any approved Ascendis products; unforeseen research and development or selling, general and administrative expenses and other costs impacting Ascendis' business generally; market acceptance, pricing, and reimbursement challenges, including payer coverage decisions and health technology assessments; competitive developments, including new or improved therapies; intellectual property protection, freedom--to--operate, and litigation risks; Ascendis' ability to obtain additional funding, if needed, to support its business activities; cybersecurity, data privacy, and information technology disruptions; and the impact of international economic, political, legal, compliance, public health, and business factors, including tariffs, trade policies, currency fluctuations, and geopolitical events. For a further description of the risks and uncertainties that could cause actual results to differ from those expressed in these forward-looking statements, as well as risks relating to Ascendis' business in general, see Ascendis' Annual Report on Form 20-F filed with the U.S. Securities and Exchange Commission (SEC) on February 11, 2026, and Ascendis' other future reports filed with, or submitted to, the SEC. Forward-looking statements do not reflect the potential impact of any future licensing, collaborations, acquisitions, mergers, dispositions, joint ventures, or investments that Ascendis may enter into or make. Ascendis does not assume any obligation to update any forward-looking statements, except as required by law.

Ascendis, Ascendis Pharma, the Ascendis Pharma logo, the company logo, TransCon, SKYTROFA(R) , YORVIPATH(R) , and YUVIWEL(R) are trademarks owned by the Ascendis Pharma group. (c) May 2026 Ascendis Pharma A/S.

 
Investor Contacts:  Media Contact: 
------------------  ----------------- 
Chad Fugere         Melinda Baker 
Ascendis Pharma     Ascendis Pharma 
+1 (650) 519-7494   +1 (650) 709-8875 
 
 
 
FINANCIAL TABLES FOLLOW 
----------------------- 
 
 
 
Ascendis Pharma A/S Unaudited Condensed 
Consolidated Statements of Profit or (Loss) and 
Comprehensive Income / (Loss) (In EUR'000s,         Three Months Ended 
except per share data)                                   March 31, 
                                                  ---------------------- 
                                                    2026        2025 
                                                  ---------  ----------- 
Consolidated Statement of Profit or (Loss) 
Revenue                                            246,601    100,954 
Cost of sales                                      (17,515)   (17,517) 
                                                  --------   -------- 
Gross profit                                       229,086     83,437 
Research and development expenses                  (59,044)   (86,603) 
Selling, general, and administrative expenses     (145,230)  (101,046) 
                                                  --------   -------- 
Operating profit/(loss)                             24,812   (104,212) 
Share of profit/(loss) of associates               (10,251)    26,579 
Finance income                                       4,517     28,854 
Finance expenses                                   (67,255)   (44,786) 
                                                  --------   -------- 
Profit/(loss) before tax                           (48,177)   (93,565) 
Income taxes (expenses)                            677,516     (1,061) 
                                                  --------   -------- 
Net profit/(loss) for the period                   629,339    (94,626) 
                                                  ========   ======== 
Attributable to owners of the Company              629,339    (94,626) 
                                                  --------   -------- 
Basic earnings/(loss) per share                      10.20      (1.58) 
Diluted earnings/(loss) per share                     9.75      (1.58) 
                                                  --------   -------- 
 
 
Consolidated Statement of Comprehensive Income 
or (Loss) 
Net profit/(loss) for the period                   629,339    (94,626) 
Other comprehensive income/(loss) 
Items that may be reclassified subsequently to 
profit or (loss): 
Exchange differences on translating foreign 
 operations                                          3,058        (75) 
                                                  --------   -------- 
Other comprehensive income/(loss) for the 
 period, net of tax                                  3,058        (75) 
                                                  --------   -------- 
Total comprehensive income/(loss) for the 
 period, net of tax                                632,397    (94,701) 
                                                  ========   ======== 
Attributable to owners of the Company              632,397    (94,701) 
                                                  --------   -------- 
 
 
 
Ascendis Pharma A/S Unaudited Condensed 
Consolidated Statements of Financial         March 31,   December 31, 
Position (In EUR'000s)                          2026         2025 
                                             ---------  -------------- 
 
Assets 
Non-current assets 
Intangible assets                                3,689        3,710 
Property, plant and equipment                  135,918      146,479 
Investments in associates                       23,560       32,526 
Other receivables                               27,367       10,870 
Deferred tax assets                            690,405           -- 
 
                                               880,939      193,585 
                                             ---------  ----------- 
Current assets 
Inventories                                    314,342      301,533 
Trade receivables                              178,676      141,333 
Income tax receivables                           1,258        1,781 
Other receivables                               16,673       14,582 
Prepayments                                     38,571       33,715 
Cash and cash equivalents                      572,820      616,041 
                                             ---------  ----------- 
                                             1,122,340    1,108,985 
                                             ---------  ----------- 
Total assets                                 2,003,279    1,302,570 
                                             =========  =========== 
 
Equity and liabilities 
Equity 
Share capital                                    8,380        8,322 
Distributable equity                           479,593     (171,143) 
                                             ---------  ----------- 
Total equity                                   487,973     (162,821) 
                                             ---------  ----------- 
 
Non-current liabilities 
Borrowings                                     386,106      385,254 
Contract liabilities                             2,437        1,123 
Deferred tax liabilities                            --        9,623 
                                             ---------  ----------- 
                                               388,543      396,000 
                                             ---------  ----------- 
Current liabilities 
Convertible notes, due April 2028 
Borrowings                                     448,176      429,391 
Derivative liabilities                         290,482      256,231 
                                             ---------  ----------- 
                                               738,658      685,622 
Other current liabilities 
Borrowings                                      62,382       57,141 
Contract liabilities                             5,364        4,944 
Trade payables and accrued expenses             78,588       90,657 
Other liabilities                               57,316       58,204 
Income tax payables                              7,805        6,427 
Provisions                                     176,650      166,396 
                                             ---------  ----------- 
                                               388,105      383,769 
                                             ---------  ----------- 
                                             1,126,763    1,069,391 
                                             ---------  ----------- 
Total liabilities                            1,515,306    1,465,391 
                                             ---------  ----------- 
Total equity and liabilities                 2,003,279    1,302,570 
                                             =========  =========== 
 
 
 
Ascendis Pharma A/S Unaudited Condensed 
Consolidated Statements of Cash Flow (In            Three Months Ended 
EUR'000s)                                                March 31, 
                                                  ---------------------- 
                                                     2026        2025 
                                                  ----------  ---------- 
Operating activities 
Net profit/(loss) for the period                    629,339   (94,626) 
Reversal of finance income                           (4,517)  (28,854) 
Reversal of finance expenses                         67,255    44,786 
Reversal of income taxes                           (677,516)    1,061 
Adjustments for non-cash items: 
    Non-cash consideration relating to revenue         (638)   (1,402) 
    Share of (profit)/loss of associates             10,251   (26,579) 
    Share-based payment                              30,356    25,558 
    Depreciation and amortization                     4,220     4,545 
    Impairment of property, plant and equipment          --     7,508 
Changes in working capital: 
    Inventories                                     (12,813)    2,538 
    Receivables                                     (36,377)   98,032 
    Prepayments                                      (4,852)   (5,521) 
    Contract liabilities                              1,735    (4,054) 
    Trade payables, accrued expenses and other 
     liabilities                                    (21,051)  (40,767) 
    Provisions                                        6,534       260 
                                                  ---------   ------- 
Cash flows generated from/(used in) operations       (8,074)  (17,515) 
Finance income received                               4,518     4,208 
Finance expenses paid                                (5,328)     (954) 
Income taxes received/(paid)                          1,163       (52) 
Cash flows from/(used in) operating activities       (7,721)  (14,313) 
                                                  ---------   ------- 
Investing activities 
Payments received under finance leases                  959        -- 
Acquisition of intangible assets and property, 
 plant and equipment                                 (7,712)     (703) 
Cash flows from/(used in) investing activities       (6,753)     (703) 
                                                  ---------   ------- 
Financing activities 
Repayment of borrowings                              (8,580)   (3,066) 
Proceeds from exercise of warrants                   31,625    13,834 
Acquisition of treasury shares                      (51,857)  (17,396) 
Payment of withholding taxes under stock 
 incentive programs                                  (8,021)  (11,396) 
Cash flows from/(used in) financing activities      (36,833)  (18,024) 
                                                  ---------   ------- 
 
Increase/(decrease) in cash and cash equivalents    (51,307)  (33,040) 
Cash and cash equivalents at January 1              616,041   559,543 
Effect of exchange rate changes on balances held 
 in foreign currencies                                8,086    (8,580) 
Cash and cash equivalents at March 31               572,820   517,923 
                                                  ---------   ------- 
 
 

Non-IFRS Financial Measures

In addition to the financial information prepared in accordance with IFRS Accounting Standards ("IFRS") as issued by the International Accounting Standards Board and as adopted by the European Union, this press release contains certain non-IFRS financial measures, including Non-IFRS Operating Profit/(Loss), Non-IFRS Net Profit/(Loss), Non-IFRS operating profit/(loss) margin, and Non-IFRS diluted earnings per share ("Non-IFRS Diluted EPS"). These non-IFRS measures are provided as supplemental information and should be considered in addition to, and not as a substitute for or superior to, the comparable measures prepared in accordance with IFRS. Management believes these non-IFRS measures support management's, analysts' and investors' overall understanding of the Company's underlying financial performance and trends and facilitate comparisons among current and past periods.

Since non-IFRS measures do not have standardized definitions and meanings, they may differ from the non-IFRS measures used by other companies, which reduces their usefulness as comparative financial measures. Because of these limitations, you should consider these adjusted financial measures alongside other IFRS financial measures. Because these non-IFRS measures are not prepared in accordance with IFRS, they should not be viewed as superior to IFRS reported measures, nor should they be used on their own or as replacements for the IFRS financial information included in this press release. Additionally, our non-IFRS measures may differ from similarly labeled measures used by other companies due to variations in calculation methods or the size and nature of adjusted items. Investors should note that several of the items excluded from these non-IFRS measures have been recognized in prior periods and may continue to be recognized in future periods.

The Company reports Non-IFRS Operating Profit/(Loss), Non-IFRS Net Profit /(Loss), Non-IFRS operating profit/(loss) margin and Non-IFRS Diluted EPS as non-IFRS measures, which exclude the following specified items:

(i) Share-based compensation expense. Although share-based compensation is a recurring expense, the Company excludes it from non-IFRS measures because the amount and timing of recognition depend on the value of the underlying equity instruments, which can fluctuate based on factors unrelated to the Company's operating performance during the period.

(ii) Share of profit/(loss) of associates. The Company excludes its share of the profit or loss of equity-method investees because these amounts are not within the control of the Company and do not reflect the Company's core operating performance.

(iii) Fair-value remeasurement of derivative liabilities related to the Company's convertible notes. The Company excludes the fair-value remeasurement of derivative liabilities associated with its convertible notes because these amounts depend on movements in the Company's share price and other market inputs and are not indicative of the Company's underlying operating performance.

(iv) Recognition of previously unrecognized deferred tax assets. The Company excludes the one-time recognition of previously unrecognized deferred tax assets because this item reflects a reassessment of the recoverability of historical tax attributes rather than the Company's current period operating performance.

Income taxes related to the foregoing items are adjusted accordingly, considering the individual impact of each item, the relevant tax jurisdiction, applicable tax rates, and the deductibility of the item.

For further details regarding valuation of derivative liabilities, and the recognition of previously unrecognized deferred tax assets, please refer to "Note 3 -- Significant Accounting Judgements and Estimates," contained in our Interim Report on Form 6-K, for the period ended March 31, 2026 and "Note 3 -- Significant Accounting Judgements and Estimates, " contained in our Annual Report on Form 20-F, for the year ended December 31, 2025.

The following table provides a reconciliation of the most directly comparable IFRS measures to Non-IFRS Operating Profit/(Loss), Non-IFRS Net Profit/(Loss) and Non-IFRS Diluted EPS.

 
 
                          Ascendis Pharma A/S 
        Reconciliation of IFRS to Non-IFRS Financial Information 
          (unaudited, in EUR'000s, except shares and per share 
                                  data) 
 
                                                Three Months Ended 
                                                    March 31, 
 
                                               2026            2025 
                                          --------------  -------------- 
 
IFRS operating profit/(loss)                  24,812        (104,212) 
    Share-based compensation costs            30,356          25,558 
                                          ----------      ---------- 
Total non-IFRS adjustments to operating 
 profit/(loss)                                30,356          25,558 
                                          ----------      ---------- 
Non-IFRS operating profit/(loss)              55,168         (78,654) 
                                          ==========      ========== 
 
IFRS operating profit/(loss) margin 
 (%)(1)                                         10.1%         (103.2%) 
Non-IFRS operating profit/(loss) margin 
 (%)(1)                                         22.4%          (77.9%) 
 
 
IFRS Net profit/(loss)                       629,339         (94,626) 
    Share-based compensation costs            30,356          25,558 
    Share of profit/(loss) of associates      10,251         (26,579) 
    Remeasurement gain/(loss) of 
     derivative liabilities                   34,251          23,911 
    Recognition of previously 
     unrecognized deferred tax assets       (679,024)              - 
    Tax effects of adjustments                (7,623)         (1,640) 
Total non-IFRS adjustments to net 
 profit/(loss)                              (611,789)         21,250 
                                          ----------      ---------- 
Non-IFRS net profit/(loss)                    17,550         (73,376) 
                                          ==========      ========== 
 
Net profit/(loss) per diluted share: 
  IFRS                                          9.75           (1.58) 
  Diluted per share impact of total 
   non-IFRS adjustments                        (9.48)           0.35 
  Non-IFRS                                      0.27           (1.22) 
 
Shares used in diluted per share 
calculation: 
  IFRS                                    64,521,948      60,018,550 
  Non-IFRS                                64,521,948      60,018,550 
 
(1) Defined as either IFRS or non-IFRS 
 operating profit/(loss) divided by 
 total revenue 
 

(END) Dow Jones Newswires

May 07, 2026 07:30 ET (11:30 GMT)

At the request of the copyright holder, you need to log in to view this content

Disclaimer: Investing carries risk. This is not financial advice. The above content should not be regarded as an offer, recommendation, or solicitation on acquiring or disposing of any financial products, any associated discussions, comments, or posts by author or other users should not be considered as such either. It is solely for general information purpose only, which does not consider your own investment objectives, financial situations or needs. TTM assumes no responsibility or warranty for the accuracy and completeness of the information, investors should do their own research and may seek professional advice before investing.

Most Discussed

  1. 1
     
     
     
     
  2. 2
     
     
     
     
  3. 3
     
     
     
     
  4. 4
     
     
     
     
  5. 5
     
     
     
     
  6. 6
     
     
     
     
  7. 7
     
     
     
     
  8. 8
     
     
     
     
  9. 9
     
     
     
     
  10. 10