On August 14, LEADS BIOLABS-B rose 5.06% in regular trading, trading at HK$72.3/share, with turnover of HK$119 million.
The movement was driven by a cluster of recent positive developments. On August 6, the company announced that its core product Welixin (Opamtistomig, a PD-L1/4-1BB bispecific antibody) Phase II clinical study for first-line hepatocellular carcinoma treatment successfully entered the expansion stage following safety lead-in evaluation. Additionally, the IND application for Welixin in metastatic colorectal cancer was approved by CDE on August 3, and the Phase II biliary tract cancer study completed enrollment of all 70 patients on July 30.
Further catalysts include Zhejiang Securities initiating coverage with a Buy rating, projecting revenue of RMB 284-756 million for 2026-2028. The BLA for Welixin was previously accepted into priority review, and six research results were selected for the ESMO annual meeting, reinforcing pipeline value realization and commercial visibility.
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