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SPYRE THERAPEUTICS INC

80.45

-5.4500-6.34%

盘后：80.450.00000.00%19:30 EDT

成交量：144.11万

成交额：1.19亿

市值：74.25亿

市盈率：-40.03

高：85.32

开：85.12

低：80.45

收：85.90

52周最高：110.18

52周最低：18.71

股本：9,229.14万

流通股本：8,161.70万

量比：0.64

换手率：1.77%

股息：- -

股息率：- -

每股收益(TTM):-2.0100

每股收益(LYR):-1.9755

净资产收益率：-22.98%

总资产收益率：-19.81%

市净率：7.78

市盈率(LYR):-40.72

数据加载中...

总览公司新闻资讯公告

异动解读｜Spyre Therapeutics盘中上涨6.15%，生物科技板块整体走强

Spyre Therapeutics因3.5亿美元股票发行而股价下跌

BUZZ——美股行情动态-Pyxis Oncology、MongoDB、United Therapeutics

默克公司药物在皮肤病临床试验中取得成功，Spyre股价上涨

异动解读｜Spyre Therapeutics盘中上涨6.21%，IBD管线三大靶点概念验证全部完成提振市场信心

Spyre Therapeutics旗下Spy003疗法在第12周实现20%临床缓解率及30%内镜改善率

BUZZ——美国股市动态-Semtech、唐纳森、Meta

Spyre股价下跌，因关节炎药物未达研发目标

Spyre Therapeutics盘前股价重挫12.4% 实验性药物未达类风湿关节炎单药治疗开发门槛

Spyre Therapeutics公司——疗效幅度未达公司预设目标，类风湿关节炎候选药物SPY072单药疗法开发优先级或将调整

Spyre Therapeutics公司：Spy072联合Il17-a/F治疗化脓性汗腺炎（HS）预计于2027年末或2028年初启动

Spyre Therapeutics——Spy072在多项终点指标上较安慰剂展现统计学显著优势

Spyre Therapeutics公布Spy072 Skyway二期试验类风湿关节炎亚研究顶线结果

美国研究综述-Accendra Health、Celestica、Sionna Therapeutics

Spyre Therapeutics推出Spy772项目，启动化脓性汗腺炎SkyLight二期临床试验

异动解读｜Spyre Therapeutics盘中上涨11.41%，报104.42美元

异动解读｜Spyre Therapeutics盘中上涨5.02%，报93.505美元

异动解读｜SPYRE THERAPEUTICS盘前下跌5.04%，董事减持持续施压股价

异动解读｜Spyre Therapeutics盘中下跌14.76%，董事减持引发市场关注

异动解读｜SPYRE THERAPEUTICS盘前下跌10.83%，报86.54美元

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Therapeutics（SYRE.O）股价在盘前交易中下跌4.1%，报88.90美元，此前该公司定价完成了一笔3.5亿美元的后续融资** 这家生物技术公司于周一晚间宣布 (link)，以每股85美元的价格发行约410万股，较最后成交价折让8.3%** 该公司计划将募集资金净额用于推进其胃肠","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20261006:nL4S45S0QN:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"shareholding","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU2324357040.USD","LU1934455863.HKD","LU2360032135.SGD","LU0942090050.USD","LU0203345920.USD","IE00BBT3K403.USD","LU2125154935.USD","LU2023250843.SGD","LU0965508806.USD","SG9999001440.SGD","IXJ","LU2106854487.HKD","GDOC","LU1066051498.USD","BK4007","LU1069347547.HKD","LU0289961442.SGD","TRUH","IE00BSNM7G36.USD","LU1934455194.USD","PAWZ","LU2433249047.HKD","LU0130102774.USD","LU1093756325.SGD","LU2491050154.USD","VHT","IYH","LU0868494708.USD","LU1066051811.HKD","BK4559","LU1923622614.USD","LU1929549753.HKD","LFSC","FHLC","LU1116320901.HKD","LU0965509101.SGD","LU0432979614.USD","LU0006306889.USD","LU0985320562.USD","LU0072461881.USD","MRK","LU1941712348.USD","LU1032466523.USD","LU0472753341.HKD","XLV","LU0265550946.USD","SG9999014575.USD","SG9999001176.SGD","LU1934455277.USD","LU1989772923.USD","IE0002141913.USD","IHE","LU0211331839.USD","LU1585245621.USD","IE00BJT1NW94.SGD","LU0106261372.USD","FTXH","LU1037948541.HKD","LU0130517989.USD","LU0069063385.USD","IE00B2B36J28.USD","LU0203347892.USD","LU0511384066.AUD","BK4550","LU1057294990.SGD","BK4534","BK4585","LU0057025933.USD","LU0266013472.USD","LU0320765646.SGD","LU2361044865.SGD","LU1699723380.USD","SG9999014567.USD","LU0162691827.USD","LU1066053197.SGD","SG9999013999.USD","SG9999002224.SGD","LU0265550359.USD","IE000M9KFDE8.USD","LU1571399168.USD","IE00B4R5TH58.HKD","BK4516","LU1066051225.USD","LU2112291526.USD","LU0477156953.USD","IE00BN8TJ469.HKD","LU0238689110.USD","LU2361045086.USD","LU2491049909.HKD","LU0823416689.USD","LU1201861249.SGD","LU1162221912.USD","LU2461242641.AUD","LU0980610538.SGD","SG9999014542.SGD","BMED","LU1974910355.USD","LU1983299246.USD","LU2125154778.USD","LU0689626769.HKD","SG9999001176.USD","LU0124676726.USD","LU0058720904.USD","LU2456880835.USD","LU0098860793.USD","LU2468319806.SGD","LU2125909593.SGD","LU0289739343.SGD","SG9999015358.SGD","LU2417539215.USD","LU2023250504.SGD","IE00BJJMRZ35.SGD","LU1093756168.USD","BK4588","LU1291159041.SGD","LU0289739699.SGD","LU0234572021.USD","HRTS","SYRE","LU0965509010.AUD","LU2125909247.SGD","LU1023059063.AUD","IE00B1BXHZ80.USD","LU0868494617.USD","BK4533","LU1037948897.HKD","LU2236285917.USD","LU0648001328.SGD","PPH","JDOC","LU2491050071.SGD","LU1941712264.USD","LU1989772840.SGD","LU2357627491.SGD","LU1116320737.USD","LU2089984988.USD","LU0070302665.USD","SG9999015341.SGD","LU1430594728.SGD","LU1035773651.USD","IE00BLSP4452.SGD","RXL","LU0965509283.SGD","LU0208291251.USD","LU0320765489.SGD","LU1989771016.USD","IE00BFTCPJ56.SGD","BK4139","LU2361044949.HKD","LU0859254822.USD","LU0122379950.USD","LU0861579265.USD","LU1061106388.HKD","SG9999002232.USD","LU1917777945.USD","SG9999014559.SGD","SGXZ57979304.SGD","IE0009355771.USD","IE00BLSP4239.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2672818267","title":"BUZZ——美股行情动态-Pyxis Oncology、MongoDB、United Therapeutics","url":"https://stock-news.laohu8.com/highlight/detail?id=2672818267","media":"路透中文","labels":["event"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2672818267?lang=zh_cn&edition=fundamental","pubTime":"2026-10-01 01:49","pubTimestamp":1790790584,"startTime":"0","endTime":"0","summary":".N美国东部时间13:30，道琼斯工业平均指数.DJI下跌0.27%，报51,213.50点；标普500指数.SPX上涨0.37%，报7,699.00点；纳斯达克综合指数.IXIC上涨0.79%，报27,008.08点。","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260930:nL4S45M1KO:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"event","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["CALM","TNON","UTHR","SNPS","CMMB","DKI","HPE","AMZN","CAG","GME","GO","SYRE","MAT","CELC","CMCT","AMZY","CNXC","EXPE","MDB","PEBO","CAPR","CVRX","HOOD","MU","ACCV","SES","MRNA","NCLH","UTES","YSG","SPCX","JBL","BA","HIG","RFL","GLAS","LQDA","FDS","FTXL","CEG","ELMT","GIS","LESL","LESLQ","PYXS","LITE","MRK","CRPT","TGE","WSPC"],"isVideo":false,"video":null,"gpt_icon":1},{"id":"2671678345","title":"默克公司药物在皮肤病临床试验中取得成功，Spyre股价上涨","url":"https://stock-news.laohu8.com/highlight/detail?id=2671678345","media":"路透中文","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2671678345?lang=zh_cn&edition=fundamental","pubTime":"2026-09-30 23:00","pubTimestamp":1790780436,"startTime":"0","endTime":"0","summary":"BUZZ-默克公司药物在皮肤病临床试验中取得成功，Spyre股价上涨9月30日-** Spyre Therapeutics（SYRE.O）股价上涨6.08%，至89.87美元** 默克公司（MRK.N）的实验性药物tulisokibart可显著减轻患有慢性皮肤病“化脓性汗腺炎”（(link)）患者的炎症性皮肤病变** 分析师表示，该数据验证了TL1A类药物的有效性，并支持Spyre针对同一信号通路","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260930:nL4T45M1CW:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU1699723380.USD","LU2361044949.HKD","LU1066051811.HKD","LU2360032135.SGD","SG9999013999.USD","IE00BFTCPJ56.SGD","IE0002141913.USD","LU0868494708.USD","BK4559","LU1037948897.HKD","LU1032466523.USD","LU2125909593.SGD","SG9999001176.SGD","LU1989772840.SGD","LU0942090050.USD","LU2023250843.SGD","SG9999001440.SGD","IHE","IE00BLSP4239.USD","FTXH","XLV","GDOC","LU0320765646.SGD","IYH","LU0069063385.USD","FHLC","LU0477156953.USD","VHT","LU0072461881.USD","BK4534","LU1917777945.USD","LU0868494617.USD","LU1066051498.USD","IE00BJT1NW94.SGD","LU2112291526.USD","HRTS","LU1035773651.USD","PAWZ","LU1989772923.USD","LU2468319806.SGD","SG9999014567.USD","SYRE","LU1934455277.USD","LU1023059063.AUD","LU1061106388.HKD","LU2361045086.USD","LU0006306889.USD","LU2433249047.HKD","SG9999014559.SGD","LU1162221912.USD","LU0162691827.USD","LU1585245621.USD","BK4139","BK4533","LU2023250504.SGD","LU0965509283.SGD","LU0070302665.USD","SG9999002224.SGD","IE00B2B36J28.USD","LU0265550359.USD","IE00BBT3K403.USD","IE00B1BXHZ80.USD","IE00BSNM7G36.USD","LU2125154935.USD","LU2491050071.SGD","BK4007","LU0289739343.SGD","IE00BN8TJ469.HKD","LU2361044865.SGD","LU2491049909.HKD","LU1941712348.USD","LU0320765489.SGD","LU0098860793.USD","LU1069347547.HKD","BK4588","LU2324357040.USD","LU1929549753.HKD","LU1989771016.USD","LU0823416689.USD","LU2491050154.USD","LU0289961442.SGD","LU0980610538.SGD","LU1093756168.USD","LU1066051225.USD","IE00BJJMRZ35.SGD","RXL","LU2089984988.USD","LU0965509010.AUD","LU0861579265.USD","LU0965508806.USD","MRK","LU1066053197.SGD","LU0432979614.USD","LU1037948541.HKD","LU0265550946.USD","LU0985320562.USD","LU1571399168.USD","LU1974910355.USD","LU0211331839.USD","LU0130517989.USD","LU0130102774.USD","LU0234572021.USD","SG9999014575.USD","LU0266013472.USD","BK4516","LU0689626769.HKD","IE00B4R5TH58.HKD","LU2461242641.AUD","LU2125154778.USD","LU1057294990.SGD","BK4550","LU1934455194.USD","SGXZ57979304.SGD","LU0511384066.AUD","LU1430594728.SGD","LU0058720904.USD","LU0472753341.HKD","SG9999002232.USD","BK4585","LU0122379950.USD","LU0965509101.SGD","PPH","JDOC","TRUH","LU1116320901.HKD","SG9999014542.SGD","LU1116320737.USD","BMED","LU0203347892.USD","LU0057025933.USD","LU0289739699.SGD","IE000M9KFDE8.USD","LU2106854487.HKD","LU0124676726.USD","LU0238689110.USD","LU2125909247.SGD","LU2357627491.SGD","LU0203345920.USD","SG9999015358.SGD","IE00BLSP4452.SGD","LU1201861249.SGD","LU1093756325.SGD","SG9999001176.USD","LU1983299246.USD","LU1941712264.USD","LU0208291251.USD","LU0648001328.SGD","LU1291159041.SGD","LU1923622614.USD","LFSC","SG9999015341.SGD","IE0009355771.USD","LU1934455863.HKD","IXJ","LU0859254822.USD","LU0106261372.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1122225330","title":"异动解读｜Spyre Therapeutics盘中上涨6.21%，IBD管线三大靶点概念验证全部完成提振市场信心","url":"https://stock-news.laohu8.com/highlight/detail?id=1122225330","media":"行情直击","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1122225330?lang=zh_cn&edition=fundamental","pubTime":"2026-09-30 22:47","pubTimestamp":1790779633,"startTime":"0","endTime":"0","summary":"9月30日，Spyre Therapeutics盘中上涨6.21%，报89.98美元/股，成交额4579.69万美元。消息面上，公司此前公布SPY003在SKYLINE二期试验中达到主要终点，治疗12周时患者Robarts组织病理学指数降低10分，临床缓解率达20%，内镜改善率达30%，安全性与IL-23类药物一致。这一结果标志着公司IBD战略中α4β7、TL1A、IL-23三大靶点均已完成临床概念验证，SKYLINE试验B部分已开始入组，预计顶线数据将于明年公布。","market":"hk","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":"Spyre 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Therapeutics日前宣布，其研发管线中的关键候选药物Spy003在临床试验中交出了令人瞩目的阶段性答卷。数据显示，在接受治疗满12周的时间节点上，该疗法成功促成了20%的患者达到临床缓解状态，与此同时，30%的受试者在内镜检查中观察到了显著的病情改善迹象。这一成果不仅彰显了Spy003在疾病修饰层面的潜在威力，也为公司后续的注册性临床推进注入了强劲信心。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LFSC","SYRE","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2662571159","title":"BUZZ——美国股市动态-Semtech、唐纳森、Meta","url":"https://stock-news.laohu8.com/highlight/detail?id=2662571159","media":"路透中文","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2662571159?lang=zh_cn&edition=fundamental","pubTime":"2026-08-26 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实验性药物未达类风湿关节炎单药治疗开发门槛","url":"https://stock-news.laohu8.com/highlight/detail?id=1103784641","media":"美股速递","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1103784641?lang=zh_cn&edition=fundamental","pubTime":"2026-08-26 17:00","pubTimestamp":1787734809,"startTime":"0","endTime":"0","summary":"Spyre Therapeutics股价在盘前交易时段大幅下跌12.4%，此前该公司宣布其一款实验性药物未能达到类风湿关节炎单药治疗开发所需的疗效阈值。这一消息令市场投资者颇感意外，引发对该生物科技公司研发管线前景的重新评估。受此利空冲击，该股在常规交易开始前即遭遇显著抛售压力，反映出市场对候选药物临床价值的疑虑正在加深。分析人士指出，未能跨越预设的疗效门槛意味着该药物作为单一疗法的开发路径将面临重大调整，公司或需重新考量其战略布局。投资者正密切关注公司后续的研发决策及可能的替代方案。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","LFSC","SYRE"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1158063890","title":"Spyre 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Therapeutics公司近日披露，其类风湿关节炎在研药物SPY072在临床试验中展现的疗效幅度未能达到公司预先设定的目标阈值。这一结果意味着，该公司此前规划的单药疗法开发路径——即将SPY072作为独立治疗方案推进的优先策略——如今面临重新审视与调整的现实压力。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LFSC","SYRE","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1107207144","title":"Spyre Therapeutics公司：Spy072联合Il17-a/F治疗化脓性汗腺炎（HS）预计于2027年末或2028年初启动","url":"https://stock-news.laohu8.com/highlight/detail?id=1107207144","media":"美股速递","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1107207144?lang=zh_cn&edition=fundamental","pubTime":"2026-08-26 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Therapeutics。股票条目按字母顺序排列。","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260811:nL4S4480H4:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SION","EPAI","AMAT","SCHH","IETC","SHOC","AFG","ACH","ETSY","CLS","HIMS","PRI","SKWD","ROOT","MET","LIF","HEAL","DKNG","LYFT","SPG","PBE","AIOT","KLAC","INTU","RCKT","PRU","RPD","BBIO","EBAY","VRTX","RGA","SYRE","LRCX","DASH","NABL","VNQ","TENX","PUBM","CEVA","MO","THNR","CLBK","MKTX","TEK","ORKA","DKUP","EQH","AFL","EXPE","WBTN"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1150250995","title":"Spyre Therapeutics推出Spy772项目，启动化脓性汗腺炎SkyLight二期临床试验","url":"https://stock-news.laohu8.com/highlight/detail?id=1150250995","media":"美股速递","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1150250995?lang=zh_cn&edition=fundamental","pubTime":"2026-08-10 20:01","pubTimestamp":1786363318,"startTime":"0","endTime":"0","summary":"Spyre Therapeutics（股票代码：SYRE）正式宣布，其全新研发项目Spy772已启动，并同步开启针对化脓性汗腺炎（Hidradenitis Suppurativa）的SkyLight二期临床试验。这一消息标志着公司在炎症性疾病治疗领域迈出关键一步。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","SYRE","LFSC"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1177727349","title":"异动解读｜Spyre Therapeutics盘中上涨11.41%，报104.42美元","url":"https://stock-news.laohu8.com/highlight/detail?id=1177727349","media":"行情直击","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1177727349?lang=zh_cn&edition=fundamental","pubTime":"2026-07-15 00:01","pubTimestamp":1784044892,"startTime":"0","endTime":"0","summary":"7月15日，Spyre Therapeutics盘中上涨11.41%，报104.42美元/股，成交额7429.81万美元。Spyre Therapeutics所在的生物科技行业中，个股表现分化，其中Nextcure Inc.涨213.3%，渤健公司跌8.42%，艾伯维公司跌1.24%，Shuttle Pharmaceuticals Inc涨31.42%，吉利德科学跌0.49%。Spyre Therapeutics是一家临床阶段生物技术公司，致力于通过结合同类最佳的抗体工程、合理的治疗组合以及精准医疗方法，开发下一代炎症性肠病产品，管线涵盖针对α4β7、TL1A和IL-23的延长半衰期抗体。","market":"hk","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SYRE"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1193512223","title":"异动解读｜Spyre Therapeutics盘中上涨5.02%，报93.505美元","url":"https://stock-news.laohu8.com/highlight/detail?id=1193512223","media":"行情直击","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1193512223?lang=zh_cn&edition=fundamental","pubTime":"2026-07-08 00:15","pubTimestamp":1783440956,"startTime":"0","endTime":"0","summary":"7月8日，Spyre Therapeutics盘中上涨5.02%，报93.505美元/股，成交额3902.22万美元。Spyre Therapeutics所在的生物科技行业中，个股中，福泰制药跌1.11%，艾伯维公司涨0.99%，吉利德科学涨3.70%，Moderna跌3.34%，安进涨0.46%。Spyre Therapeutics是一家临床阶段生物技术公司，旨在通过结合同类最佳的抗体工程、合理的治疗组合以及精准医疗方法，创造下一代炎症性肠病产品，产品线包括针对α4β7、TL1A和IL-23的延长半衰期抗体。","market":"hk","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SYRE"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1121929272","title":"异动解读｜SPYRE THERAPEUTICS盘前下跌5.04%，董事减持持续施压股价","url":"https://stock-news.laohu8.com/highlight/detail?id=1121929272","media":"行情直击","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1121929272?lang=zh_cn&edition=fundamental","pubTime":"2026-06-25 16:18","pubTimestamp":1782375497,"startTime":"0","endTime":"0","summary":"6月25日，SPYRE THERAPEUTICS盘前下跌5.04%，报82.44美元/股，成交额1.8万美元。消息面上，公司董事Michael Thomas Henderson于6月22日出售2万股公司股票，总价值约200万美元，该消息于6月23日披露后持续发酵。此前交易日公司股价已大幅下挫逾13%，成交量超290万股，约为日均成交量的两倍以上。Spyre Therapeutics是一家专注于炎症性肠病的生物技术公司，产品线包括针对α4β7、TL1A和IL-23的延长半衰期抗体。","market":"hk","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SYRE"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1143725534","title":"异动解读｜Spyre Therapeutics盘中下跌14.76%，董事减持引发市场关注","url":"https://stock-news.laohu8.com/highlight/detail?id=1143725534","media":"行情直击","labels":["shareholding"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1143725534?lang=zh_cn&edition=fundamental","pubTime":"2026-06-24 21:38","pubTimestamp":1782308280,"startTime":"0","endTime":"0","summary":"6月24日，Spyre Therapeutics盘中下跌14.76%，报85.19美元/股，成交额3673.81万美元。消息面上，公司于6月23日披露内部交易情况，董事HENDERSON MICHAEL THOMAS于6月22日卖出2万股公司股票。对于一家尚处于亏损阶段、市盈率为负的临床期生物技术公司而言，高管减持信号容易放大市场对公司前景的疑虑。Spyre Therapeutics是一家专注于炎症性肠病的生物技术公司，产品线包括针对α4β7、TL1A和IL-23的延长半衰期抗体，当前市净率约12.39倍，总市值约83亿美元。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"shareholding","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SYRE"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1134617087","title":"异动解读｜SPYRE THERAPEUTICS盘前下跌10.83%，报86.54美元","url":"https://stock-news.laohu8.com/highlight/detail?id=1134617087","media":"行情直击","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1134617087?lang=zh_cn&edition=fundamental","pubTime":"2026-06-24 16:02","pubTimestamp":1782288144,"startTime":"0","endTime":"0","summary":"6月24日，SPYRE THERAPEUTICS盘前下跌10.83%，报86.54美元/股，成交额1.75万美元。SPYRE THERAPEUTICS所在的生物科技行业中，个股表现分化，艾伯维公司涨0.63%，Apogee Therapeutics涨1.44%，吉利德科学跌0.14%，安进跌0.42%，再生元制药公司涨0%。其产品线包括针对α4β7、TL1A和IL-23的延长半衰期抗体。（以上内容均基于市场公开消息，由程序或算法智能生成，仅作为股价异动提醒，不作为投资建议或交易依据。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SYRE"],"isVideo":false,"video":null,"gpt_icon":0}],"pageSize":20,"totalPage":2,"pageCount":1,"totalSize":32,"code":"91000000","status":"200"}]}}