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Replimune Group Inc.

12.11

-0.9600-7.35%

盘后：12.150.0400+0.33%19:30 EDT

成交量：163.21万

成交额：2,000.96万

市值：11.41亿

市盈率：-3.84

高：12.93

开：12.91

低：12.07

收：13.07

52周最高：16.33

52周最低：1.50

股本：9,421.96万

流通股本：7,748.56万

量比：0.89

换手率：2.11%

股息：- -

股息率：- -

每股收益(TTM):-3.1550

每股收益(LYR):-3.3828

净资产收益率：-134.29%

总资产收益率：-51.30%

市净率：10.80

市盈率(LYR):-3.58

数据加载中...

总览公司新闻资讯公告

热门话题-有报导称FDA局长马卡里可能被解职，Replimune股价应声大涨

市场快讯——美股行情动态-TransDigm、Rhythm Pharmaceuticals、英特尔

美国食品药品监督管理局（FDA）局长马卡里为该机构关于Replimune药物的决定进行辩护

FDA专家马卡里评Replimune新药：临床试验若证有效必将获批

FDA局长Marty Makary为机构对Replimune癌症药物决定辩护后，公司股价下跌5%

美国卫生部长肯尼迪与 FDA 拒绝批准 Replimune 癌症药物一事划清界限

BUZZ--美国股票走势-Allogene Therapeutics、Adobe、Williams-Sonoma

Replimune股价暴跌66.3%，因公司药物未获FDA批准，至少六家券商下调评级

BUZZ-券商观点：黑色素瘤药物再次受挫，Replimune前路艰难

BUZZ-FDA驳回药物申请致评级下调，Replimune股价重挫

美国研究综述-雪佛龙公司、福特公司、西方石油公司

美国研究综述-雪佛龙公司、福特公司、西方石油公司

Replimune股价盘前暴跌58% 两款皮肤癌疗法未获FDA批准遭多家券商降级

BUZZ-Replimune 在 FDA 拒绝批准黑色素瘤药物后暴跌

Replimune：基于FDA反馈启动Ignyte-3试验，满足加速批准所需的确证性研究要求

Replimune Group与FDA就RP1药物BLA数据集是否足以获批用于晚期癌症患者存在分歧

Replimune Group Inc. 宣布裁员，美国生产基地将大幅缩减运营规模

FDA完全回应函：Replimune溶瘤病毒疗法有效性数据不足

美国 FDA 拒绝批准 Replimune 公司治疗晚期皮肤癌的药物

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22:56","pubTimestamp":1777992980,"startTime":"0","endTime":"0","summary":"美国食品药品监督管理局局长马卡里为该机构关于Replimune药物的决定进行辩护路透5月5日 - 美国食品和药物管理局局长马卡里博士周二为该机构不批准Replimune公司REPL.O用于治疗晚期皮肤癌的药物这一决定进行了辩护。“如果你阅读我们所谓的‘完整答复信’，就会看到FDA决策逻辑的详细内容，”马卡里在接受CNBC采访时表示。Replimune股价在早盘交易中下跌5%。对于因为使用自动化翻译功能而造成的任何损害或损失，路透不承担任何责任。","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260505:nL4S41I1L2:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["REPL","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1149357008","title":"FDA专家马卡里评Replimune新药：临床试验若证有效 必将获批","url":"https://stock-news.laohu8.com/highlight/detail?id=1149357008","media":"美股速递","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1149357008?lang=zh_cn&edition=fundamental","pubTime":"2026-05-05 22:54","pubTimestamp":1777992857,"startTime":"0","endTime":"0","summary":"美国食品药品监督管理局（FDA）专家马卡里近日就Replimune Group Inc.（REPL）的新型疗法发表重磅观点。他强调，只要临床试验数据能够充分证明该药物的疗效与安全性，获得监管批准将水到渠成。\n马卡里指出，创新药物的审评核心始终围绕科学证据展开。对于Replimune这类专注于肿瘤免疫疗法的生物技术公司而言，确凿的临床数据是打通审批通道的关键基石。若中期或最终试验结果达到预设终点，监管层必将基于患者需求加速审评流程。\n这一表态为市场注入强心针，也凸显FDA对突破性疗法的开放态度。不过专家同时提醒，药物开发存在固有风险，最终结果仍取决于临床试验的具体走向。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","REPL"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1147501425","title":"FDA局长Marty Makary为机构对Replimune癌症药物决定辩护后，公司股价下跌5%","url":"https://stock-news.laohu8.com/highlight/detail?id=1147501425","media":"美股速递","labels":["policyRegulatory"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1147501425?lang=zh_cn&edition=fundamental","pubTime":"2026-05-05 22:52","pubTimestamp":1777992722,"startTime":"0","endTime":"0","summary":"在FDA局长Marty Makary公开为监管机构对Replimune Group Inc.癌症药物的审评决定进行辩护后，该公司股价应声下跌5%。\n这一市场反应凸显了投资者对监管态度的敏感程度。Makary局长的表态被视为对Replimune药物前景的重要信号，直接影响了市场情绪。\n生物科技板块往往对监管动态表现出高度敏感性。此次股价波动再次印证了这一行业特性，同时也反映出市场对Replimune特定药物研发进展的持续关注。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"policyRegulatory","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["REPL","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2629026018","title":"美国卫生部长肯尼迪与 FDA 拒绝批准 Replimune 癌症药物一事划清界限","url":"https://stock-news.laohu8.com/highlight/detail?id=2629026018","media":"路透中文","labels":["policyRegulatory"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2629026018?lang=zh_cn&edition=fundamental","pubTime":"2026-04-23 00:55","pubTimestamp":1776876938,"startTime":"0","endTime":"0","summary":"美国卫生部长肯尼迪与 FDA 拒绝批准 Replimune 癌症药物一事划清界限肯尼迪称美国食品和药物管理局局长马卡里决定不批准药物《华尔街日报》发表评论文章呼吁撤换马卡里Replimune 公司股价上涨 15%Ahmed Aboulenein/Puyaan Singh. 本月早些时候，美国食品和药物管理局拒绝批准Replimune公司的药物RP1，原因是该公司依赖于一项没有对照组的单臂研究。自美国食品和药物管理局两年内第二次否决该药物以来，Replimune 的股价已下跌了近 70%。Replimune 没有立即回应置评请求。","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260422:nL4T41522O:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"policyRegulatory","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["REPL","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2627045446","title":"BUZZ--美国股票走势-Allogene Therapeutics、Adobe、Williams-Sonoma","url":"https://stock-news.laohu8.com/highlight/detail?id=2627045446","media":"路透中文","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2627045446?lang=zh_cn&edition=fundamental","pubTime":"2026-04-13 23:45","pubTimestamp":1776095125,"startTime":"0","endTime":"0","summary":"nL6N40W0G6 ** Ocular Therapeutix Inc OCUL.O:BUZZ - 由于新眼药显示疾病控制时间更长而上涨 nL4N40W0TJ ** Spyre Therapeutics Inc SYRE.O:BUZZ - 因肠道疾病药物中期研究成功而上涨 nL6N40W0OH ** Alphabet Inc GOOGL.O：** Meta Platforms Inc META.O：** Snap Inc SNAP.N：** Pinterest Inc PINS.N：BUZZ - 因地缘政治动荡和能源价格，Stifel 下调数字广告增长预期 nL4N40W0RX ** ImageneBio Inc IMA.O:BUZZ--为资助脱发和皮肤病药物融资 3,000 万美元后股价上涨 nL4N40W0UI ** 国际商业机器公司IBM.N：BUZZ - 花旗集团开始对 IBM 进行 \"买入 \"评级。nL6N40W0O3 ** Best Buy Co Inc BBY.N:BUZZ - 因高盛将其评级双双下调至 \"卖出 \"而下滑。nL6N40W0RY ** Revolution Medicines Inc RVMD.O:BUZZ - 因胰腺癌药物","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260413:nL4T40W1DN:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["ANIP","WSM","DOW","LUV","COIN","HPE","OXY","EMN","SBUX","LYB","BIIB","NEM","OCUL","CRWV","BBY","HL","HTFL","APTV","AAL","DIOD","CAG","REPL","META","IDYA","CDE","RVMD","AVT","RIOT","UAL","MARA","ALLO","IBM","SNDK","GGLS","CVX","KYMR","XOM","PINS","LEG","DVN","TFX","IMA","GPRO","HUT","GOOGL","SYRE","ADBE","DAL","OWL"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1144491181","title":"Replimune股价暴跌66.3%，因公司药物未获FDA批准，至少六家券商下调评级","url":"https://stock-news.laohu8.com/highlight/detail?id=1144491181","media":"美股速递","labels":["policyRegulatory"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1144491181?lang=zh_cn&edition=fundamental","pubTime":"2026-04-13 21:33","pubTimestamp":1776087195,"startTime":"0","endTime":"0","summary":"Replimune Group Inc. (REPL) 股价遭遇断崖式下跌，跌幅高达66.3%。此次暴跌的直接原因是该公司的一款核心药物未能获得美国食品药品监督管理局（FDA）的批准。这一重大利空消息迅速引发市场强烈反应，导致至少六家知名券商相继下调了该公司的股票评级。\n消息传出后，投资者信心遭受重创，大量抛售盘涌现，股价应声大幅下挫。分析人士指出，FDA的否决不仅对Replimune的短期营收前景构成沉重打击，更对其产品研发管线的未来价值投下了阴影。市场正在重新评估该公司的风险与价值。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"policyRegulatory","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","REPL"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2627584464","title":"BUZZ-券商观点：黑色素瘤药物再次受挫，Replimune前路艰难","url":"https://stock-news.laohu8.com/highlight/detail?id=2627584464","media":"路透中文","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2627584464?lang=zh_cn&edition=fundamental","pubTime":"2026-04-13 20:22","pubTimestamp":1776082957,"startTime":"0","endTime":"0","summary":"4月13日 - ** ReplimuneREPL.O股价盘前下跌63.66%至1.73美元** 美国食品和药物管理局周五以研究数据不足为由，拒绝批准  Replimune 公司治疗晚期皮肤癌的药物。(为便利非英文母语者，路透将其报导自动化翻译为数种其他语言。由于自动化翻译可能有误，或未能包含所需语境，路透不保证自动化翻译文本的准确性，仅是为了便利读者而提供自动化翻译。对于因为使用自动化翻译功能而造成的任何损害或损失，路透不承担任何责任。","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260413:nL4S40W0YP:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","REPL"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2627435431","title":"BUZZ-FDA驳回药物申请致评级下调，Replimune股价重挫","url":"https://stock-news.laohu8.com/highlight/detail?id=2627435431","media":"路透中文","labels":["policyRegulatory"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2627435431?lang=zh_cn&edition=fundamental","pubTime":"2026-04-13 17:02","pubTimestamp":1776070933,"startTime":"0","endTime":"0","summary":"** ReplimuneREPL.O股价盘前大跌56%至2.09美元** 摩根大通将生物技术公司的股票评级从 \"中性 \"下调至 \"减持\"，并撤销了10美元的目标价** 摩根大通表示，美国食品和药物管理局的第二封完整回应函 凸显了对 REPL 公司治疗晚期皮肤癌药物试验设计的担忧。由于自动化翻译可能有误，或未能包含所需语境，路透不保证自动化翻译文本的准确性，仅是为了便利读者而提供自动化翻译。对于因为使用自动化翻译功能而造成的任何损害或损失，路透不承担任何责任。","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260413:nL4T40W0JG:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"policyRegulatory","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["PIPR","BK4139","BK4127","REPL","LU0053671581.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2627730438","title":"美国研究综述-雪佛龙公司、福特公司、西方石油公司","url":"https://stock-news.laohu8.com/highlight/detail?id=2627730438","media":"路透中文","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2627730438?lang=zh_cn&edition=fundamental","pubTime":"2026-04-13 16:17","pubTimestamp":1776068257,"startTime":"0","endTime":"0","summary":"美国研究综述-雪佛龙公司、福特公司、西方石油公司路透4月13日 - 华尔街证券分析师周一调整了对几家美国上市公司的评级和目标价，其中包括雪佛龙公司、福特公司和西方石油公司。要闻 * 雪佛龙公司CVX.N：加拿大皇家银行将目标价从200美元上调至220美元 * 福特F.N：加拿大皇家银行将目标价从12美元下调至11美元  * 西方石油公司OXY.N：Gerdes Energy Research将其评级从“中性”上调至“买入”。","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260413:nL4S40W0H2:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["VNOM","INTC","CRWU","CVX","NOW","KRC","RPD","SNEX","OXY","VMI","GM","SNXX","TDC","TSDD","TSYY","TSLT","F","ESS","MET","BMI","TRGP","REPL","MRVU","AVB","NOWL","TSLA","TSLP","DT","TSL","COP","VC","MRVL","PRU","INTW","STZ","TSLW","TSLI","CRWG","GEN","LINT","CPT","LNC","QLYS","RGA","CRWV","PRI","SBUX","SNDK","TSII","AFL"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2627438753","title":"美国研究综述-雪佛龙公司、福特公司、西方石油公司","url":"https://stock-news.laohu8.com/highlight/detail?id=2627438753","media":"路透中文","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2627438753?lang=zh_cn&edition=fundamental","pubTime":"2026-04-13 16:17","pubTimestamp":1776068257,"startTime":"0","endTime":"0","summary":"美国研究综述-雪佛龙公司、福特公司、西方石油公司路透4月13日 - 华尔街证券分析师周一调整了对几家美国上市公司的评级和目标价，其中包括雪佛龙公司、福特公司和西方石油公司。要闻 * 雪佛龙公司CVX.N：加拿大皇家银行将目标价从200美元上调至220美元 * 福特F.N：加拿大皇家银行将目标价从12美元下调至11美元  * 西方石油公司OXY.N：Gerdes Energy Research将其评级从“中性”上调至“买入”。","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260413:nL4T40W0H2:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SBU","RPD","GEN","NOW","INTC","CORD","RGA","TSDD","MET","COP","VMI","REPL","DT","BMI","OXY","SNEX","SNDK","INTW","TSLL","TSLA","VC","TDC","QLYS","AFL","CVX","TSLS","TRGP","TSLP","TSLI","TSLQ","KRC","TSLO","PRU","STZ","TSLR","F","MRVL","TSLG","TSII","ESS","CPT","TSL","CRWV","VNOM","PRI","TSLT","GM","SBUX","AVB","LNC"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1188277711","title":"Replimune股价盘前暴跌58% 两款皮肤癌疗法未获FDA批准遭多家券商降级","url":"https://stock-news.laohu8.com/highlight/detail?id=1188277711","media":"美股速递","labels":["policyRegulatory"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1188277711?lang=zh_cn&edition=fundamental","pubTime":"2026-04-13 16:08","pubTimestamp":1776067703,"startTime":"0","endTime":"0","summary":"生物技术公司Replimune Group Inc. (REPL) 股价在盘前交易中重挫58%，创下历史最大单日跌幅。此次暴跌源于该公司针对晚期皮肤癌的两款核心疗法未能获得美国食品药品监督管理局（FDA）的批准许可。\n至少两家知名券商随后发布紧急报告，同步下调该股投资评级。分析师指出，监管审批的挫败不仅直接影响公司短期现金流，更对其肿瘤免疫疗法的商业化前景造成实质性打击。\n市场人士认为，此次FDA的否决决定可能迫使Replimune重新调整临床开发策略。受此影响，多只生物科技ETF持仓组合中出现连锁反应，板块情绪显著受挫。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"policyRegulatory","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["REPL","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2626814515","title":"BUZZ-Replimune 在 FDA 拒绝批准黑色素瘤药物后暴跌","url":"https://stock-news.laohu8.com/highlight/detail?id=2626814515","media":"路透中文","labels":["productRelease","event"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2626814515?lang=zh_cn&edition=fundamental","pubTime":"2026-04-11 06:13","pubTimestamp":1775859221,"startTime":"0","endTime":"0","summary":"4月10日 - ** 生物技术公司Replimune REPL.O的股票在延时交易中下跌59%，至1.98美元 ** 美国食品和药物管理局说，它拒绝批准  REPL 公司治疗晚期黑色素瘤的实验性疗法** FDA称两项研究的数据不足以支持批准该疗法与百时美施贵宝BMY.N的Opdivo联合使用** 监管机构称，该申请主要依赖于单臂研究，因此很难分离出该药物在联合使用时的益处** 首席执行官苏希尔-帕特尔表示，公司别无选择，只能裁员并大幅缩减在美国的生产业务","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260410:nL4T40T1O7:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"productRelease,event","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU2133065610.SGD","LU1032466523.USD","LU0306806265.USD","LU1718418525.SGD","BMY","IE0009355771.USD","LU0456855351.SGD","LU2242646821.SGD","LU1261432733.SGD","LU0061475181.USD","IE00BFXG1179.USD","IE00BJT1NW94.SGD","LU0321505868.SGD","LU1868836591.USD","LU1868836914.USD","IE00BJJMRZ35.SGD","LU1883839398.USD","LU0321505439.SGD","BK4139","BK4532","LU1571399168.USD","BK4534","LU1291159041.SGD","LU1670711040.USD","LU1989771016.USD","LU0868494617.USD","LU1670710661.SGD","LU1868836757.USD","LU0985481810.HKD","REPL","IE00BSNM7G36.USD","LU0114720955.EUR","LU1868837300.USD","IE00B2B36J28.USD","LU2125154935.USD","LU1983299246.USD","LU2242652126.USD","LU1093756325.SGD","BK4559","IE00BFTCPJ56.SGD","LU0225284248.USD","LU0306807586.USD","LU0237698245.USD","LU1670711123.USD","BK4588","LU1074936037.SGD","LU0225771236.USD","LU0882574055.USD","LU1093756168.USD","IE0002141913.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1106873747","title":"Replimune：基于FDA反馈启动Ignyte-3试验，满足加速批准所需的确证性研究要求","url":"https://stock-news.laohu8.com/highlight/detail?id=1106873747","media":"美股速递","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1106873747?lang=zh_cn&edition=fundamental","pubTime":"2026-04-11 05:06","pubTimestamp":1775855171,"startTime":"0","endTime":"0","summary":"生物技术公司Replimune Group Inc. (REPL) 宣布，根据美国食品药品监督管理局（FDA）的反馈，公司已正式启动Ignyte-3临床试验。此举旨在满足监管机构对加速批准路径的要求，即相关确证性研究必须正在进行中。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","REPL"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1186610525","title":"Replimune Group与FDA就RP1药物BLA数据集是否足以获批用于晚期癌症患者存在分歧","url":"https://stock-news.laohu8.com/highlight/detail?id=1186610525","media":"美股速递","labels":["policyRegulatory"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1186610525?lang=zh_cn&edition=fundamental","pubTime":"2026-04-11 05:05","pubTimestamp":1775855138,"startTime":"0","endTime":"0","summary":"生物制药公司Replimune Group Inc.与美国食品药品监督管理局（FDA）在关键药物RP1的上市申请数据充分性问题上产生意见分歧。该公司认为，当前提交的生物制品许可申请（BLA）数据集已具备足够证据支持该疗法用于晚期癌症患者，但监管机构对此持保留态度。这一争议直接关系到该创新疗法能否加速惠及亟待新治疗方案的患者群体。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"policyRegulatory","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","REPL"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1110263267","title":"Replimune Group Inc. 宣布裁员，美国生产基地将大幅缩减运营规模","url":"https://stock-news.laohu8.com/highlight/detail?id=1110263267","media":"美股速递","labels":["executive"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1110263267?lang=zh_cn&edition=fundamental","pubTime":"2026-04-11 05:05","pubTimestamp":1775855113,"startTime":"0","endTime":"0","summary":"在面临严峻的经营挑战下，生物制药公司Replimune Group Inc. 今日宣布了一项艰难的决定：公司将不得不进行裁员，并大幅缩减其在美国的生产运营规模。这一举措旨在优化资源配置，以应对当前复杂的市场环境。\n公司表示，此次运营调整实属无奈之举，是确保企业长期可持续发展的重要步骤。通过精简生产结构和人员队伍，Replimune Group Inc. 希望能够更加专注于核心研发领域，为未来的增长奠定坚实基础。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"executive","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","REPL"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1130606061","title":"FDA完全回应函：Replimune溶瘤病毒疗法有效性数据不足","url":"https://stock-news.laohu8.com/highlight/detail?id=1130606061","media":"美股速递","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1130606061?lang=zh_cn&edition=fundamental","pubTime":"2026-04-10 23:23","pubTimestamp":1775834592,"startTime":"0","endTime":"0","summary":"美国食品药品监督管理局（FDA）在针对Replimune Group Inc.的完全回应函中指出，现有临床数据尚不足以证明其溶瘤病毒疗法vusolimogene oderparepvec具有显著有效性。监管机构认为，当前提交的证据未能达到\"实质性有效证明\"的审评标准，要求企业补充更多临床数据支持该疗法的疗效结论。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["REPL","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2626119984","title":"美国 FDA 拒绝批准 Replimune 公司治疗晚期皮肤癌的药物","url":"https://stock-news.laohu8.com/highlight/detail?id=2626119984","media":"路透中文","labels":["policyRegulatory"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2626119984?lang=zh_cn&edition=fundamental","pubTime":"2026-04-10 23:23","pubTimestamp":1775834585,"startTime":"0","endTime":"0","summary":"美国 FDA 拒绝批准 Replimune 公司治疗晚期皮肤癌的药物路透4月10日 - 美国食品和药物管理局周五表示，拒绝批准Replimune公司治疗晚期皮肤癌的REPL.O药物。(为便利非英文母语者，路透将其报导自动化翻译为数种其他语言。由于自动化翻译可能有误，或未能包含所需语境，路透不保证自动化翻译文本的准确性，仅是为了便利读者而提供自动化翻译。对于因为使用自动化翻译功能而造成的任何损害或损失，路透不承担任何责任。)","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260410:nL4S40T17I:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"policyRegulatory","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU1093756168.USD","LU0237698245.USD","IE00BFXG1179.USD","LU0456855351.SGD","IE00B2B36J28.USD","LU1983299246.USD","LU1670710588.SGD","LU1718418525.SGD","LU1323610961.USD","LU0225771236.USD","BK4007","LU1868836757.USD","LU2133065610.SGD","LU0114720955.EUR","LU1093756325.SGD","LU1074936037.SGD","LU1868837300.USD","IE00BJT1NW94.SGD","LU1571399168.USD","LU1032466523.USD","LU1989771016.USD","LU2242646821.SGD","IE0002141913.USD","LU0306807586.USD","LU0096364046.USD","BK4534","BK4581","LU0882574055.USD","LU1670711123.USD","LU1868836591.USD","LU0267386448.USD","LU0225284248.USD","REPL","LU2125154935.USD","LU0061475181.USD","LU1868837136.USD","LU0321505439.SGD","BK4559","LU0321505868.SGD","LU2360032135.SGD","BMY","BK4585","IE00BSNM7G36.USD","IE00BFTCPJ56.SGD","LU1585245621.USD","LU1868836914.USD","BK4588","LU1291159041.SGD","BK4139","LU2125154778.USD"],"isVideo":false,"video":null,"gpt_icon":0}],"pageSize":20,"totalPage":3,"pageCount":3,"totalSize":59,"code":"91000000","status":"200"}]}}