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Mirum Pharmaceuticals, Inc.

83.21

-2.8500-3.31%

成交量：9.22万

成交额：778.77万

市值：54.03亿

市盈率：-5.91

高：87.00

开：86.06

低：83.09

收：86.06

52周最高：130.00

52周最低：63.23

股本：6,493.22万

流通股本：5,641.51万

量比：0.39

换手率：0.16%

股息：- -

股息率：- -

每股收益(TTM):-14.0800

每股收益(LYR):-0.4700

净资产收益率：-702.97%

总资产收益率：-6.79%

市净率：-518.42

市盈率(LYR):-177.04

数据加载中...

总览公司新闻资讯公告

热门话题-Mirum Pharma股价上涨，因其肝病药物在临床试验中达到主要目标

Mirum公司治疗罕见肝病的药物在中期研究中达到主要目标

Mirum制药Volixibat安全性特征与IBAT抑制作用一致主要表现为胃肠道事件及肝酶升高

Mirum Pharmaceuticals预计2027年第一季度公布Volixibat治疗PBC的Vantage二期B阶段研究顶线数据

Mirum制药公司计划2026年夏季与FDA召开Volixibat治疗PSC的新药申请前会议拟于2026年下半年提交NDA

Mirum制药Volixibt实现瘙痒评分降低2.72分较安慰剂组优势达1.64分（P<0.0001）

Mirum Pharmaceuticals宣布Volixibat治疗原发性硬化性胆管炎的Vistas研究达到主要终点

Mirum制药宣布Brelovitug治疗慢性丁型肝炎的Azure-1研究2B阶段达成主要终点

热门话题-Mirum Pharma股价上涨，因其丁型肝炎药物达成主要目标

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Pharmaceuticals公司公布的研究数据显示，其核心候选药物volixibat的安全性特征与回肠胆汁酸转运蛋白（IBAT）抑制机制高度吻合。临床观察发现，该药物引发的不良反应主要集中于胃肠道范畴，同时伴有肝脏生化参数的可逆性升高。\n值得注意的是，这类安全性表现完全符合IBAT抑制剂类药物已知的作用机理预期。研究人员强调，胃肠道反应与肝酶指标变化均属可控范围，为后续临床开发提供了重要安全性依据。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","MIRM"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1186217776","title":"Mirum Pharmaceuticals预计2027年第一季度公布Volixibat治疗PBC的Vantage二期B阶段研究顶线数据","url":"https://stock-news.laohu8.com/highlight/detail?id=1186217776","media":"美股速递","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1186217776?lang=zh_cn&edition=fundamental","pubTime":"2026-05-04 20:05","pubTimestamp":1777896314,"startTime":"0","endTime":"0","summary":"Mirum Pharmaceuticals宣布，针对原发性胆汁性胆管炎（PBC）的Volixibat药物Vantage二期B阶段临床研究，预计将于2027年第一季度获得顶线数据结果。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["MIRM","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1156368450","title":"Mirum制药公司计划2026年夏季与FDA召开Volixibat治疗PSC的新药申请前会议 拟于2026年下半年提交NDA","url":"https://stock-news.laohu8.com/highlight/detail?id=1156368450","media":"美股速递","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1156368450?lang=zh_cn&edition=fundamental","pubTime":"2026-05-04 20:03","pubTimestamp":1777896229,"startTime":"0","endTime":"0","summary":"Mirum Pharmaceuticals, Inc.宣布，针对Volixibat用于原发性硬化性胆管炎治疗的研发取得重要进展。公司已安排于2026年夏季与美国食品药品监督管理局举行新药申请前会议，此举标志着该药物研发进入关键阶段。根据公司规划，在完成Pre-NDA会议并获取监管机构反馈后，Mirum拟于2026年下半年正式提交Volixibat治疗PSC的新药申请。此次披露的监管时间节点，不仅体现了公司对研发进程的精准把控，也预示着该药物向商业化迈出了实质性步伐。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["MIRM","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1101296019","title":"Mirum制药Volixibt实现瘙痒评分降低2.72分 较安慰剂组优势达1.64分（P<0.0001）","url":"https://stock-news.laohu8.com/highlight/detail?id=1101296019","media":"美股速递","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1101296019?lang=zh_cn&edition=fundamental","pubTime":"2026-05-04 20:03","pubTimestamp":1777896199,"startTime":"0","endTime":"0","summary":"Mirum Pharmaceuticals, Inc.旗下药物Volixibat在最新临床试验中展现出显著疗效。数据显示，该药物可使患者瘙痒评分平均降低2.72分，相较于安慰剂组取得的1.08分改善，治疗效果优势达到1.64分。这一差异具有高度统计学意义（P<0.0001），表明Volixibat在缓解瘙痒症状方面具有显著临床价值。\n研究结果进一步验证了Volixibat作为新型治疗方案的潜力。药物通过特异性作用机制靶向疾病根源，为相关患者群体提供了新的治疗选择。此次数据公布为Mirum Pharmaceuticals, Inc.后续的监管申报和商业化进程奠定了重要基础。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["MIRM","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1197260913","title":"Mirum Pharmaceuticals宣布Volixibat治疗原发性硬化性胆管炎的Vistas研究达到主要终点","url":"https://stock-news.laohu8.com/highlight/detail?id=1197260913","media":"美股速递","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1197260913?lang=zh_cn&edition=fundamental","pubTime":"2026-05-04 20:02","pubTimestamp":1777896160,"startTime":"0","endTime":"0","summary":"Mirum Pharmaceuticals宣布，其药物Volixibat在针对原发性硬化性胆管炎（PSC）患者开展的Vistas研究中，成功达到了预设的主要疗效终点。该重要里程碑标志着公司在肝胆疾病治疗领域的研发取得关键进展。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","MIRM"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1189451881","title":"Mirum制药宣布Brelovitug治疗慢性丁型肝炎的Azure-1研究2B阶段达成主要终点","url":"https://stock-news.laohu8.com/highlight/detail?id=1189451881","media":"美股速递","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1189451881?lang=zh_cn&edition=fundamental","pubTime":"2026-04-27 20:14","pubTimestamp":1777292063,"startTime":"0","endTime":"0","summary":"Mirum Pharmaceuticals, Inc. (MIRM) 今日宣布，其针对慢性丁型肝炎病毒（HDV）的创新药物Brelovitug在Azure-1临床研究的2B阶段取得了重大进展，成功达到了预设的主要疗效终点。\n这一关键性成果标志着Brelovitug在治疗这一难治性肝脏疾病的发展道路上迈出了坚实的一步。丁型肝炎是一种严重的病毒性肝炎，目前全球范围内的治疗选择极为有限。Azure-1研究2B阶段的成功，为饱受该疾病困扰的患者带来了新的希望。\n公司表示，将基于此次获得的积极数据，与监管机构进行沟通，并积极推进该药物的后续临床开发计划。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["MIRM","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2630739603","title":"热门话题-Mirum Pharma股价上涨，因其丁型肝炎药物达成主要目标","url":"https://stock-news.laohu8.com/highlight/detail?id=2630739603","media":"路透中文","labels":["shareholding","productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2630739603?lang=zh_cn&edition=fundamental","pubTime":"2026-04-27 20:11","pubTimestamp":1777291871,"startTime":"0","endTime":"0","summary":"热门话题-Mirum Pharma股价上涨，因其丁型肝炎药物达成主要目标4月27日 - ** 生物科技公司Mirum Pharmaceuticals MIRM.O的股价在盘前交易中上涨2%，报92.99美元** 该公司表示，其实验性药物brelovitug在一项针对慢性丁型肝炎的中期研究中达到了主要目标。由于自动化翻译可能有误，或未能包含所需语境，路透不保证自动化翻译文本的准确性，仅是为了便利读者而提供自动化翻译。对于因为使用自动化翻译功能而造成的任何损害或损失，路透不承担任何责任。","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260427:nL4S41A14O:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"shareholding,productRelease","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","MIRM"],"isVideo":false,"video":null,"gpt_icon":0}],"pageSize":20,"totalPage":2,"pageCount":2,"totalSize":29,"code":"91000000","status":"200"}]}}